Search: ((WFRF:(James P)) pers:(Salomaa Veikko) pers:(Peltonen Leena) lar1:(uu) pers:(Soranzo Nicole) pers:(Wright Alan F) pers:(Ridker Paul M.)) >
Association analyse...
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
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Speliotes, Elizabeth K. (author)
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Willer, Cristen J. (author)
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Berndt, Sonja I. (author)
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show more...
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Monda, Keri L. (author)
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Thorleifsson, Gudmar (author)
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Jackson, Anne U. (author)
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Allen, Hana Lango (author)
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Lindgren, Cecilia M. (author)
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Luan, Jian'an (author)
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Maegi, Reedik (author)
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Randall, Joshua C. (author)
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Vedantam, Sailaja (author)
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Winkler, Thomas W. (author)
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Qi, Lu (author)
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Workalemahu, Tsegaselassie (author)
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Heid, Iris M. (author)
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Steinthorsdottir, Valgerdur (author)
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Stringham, Heather M. (author)
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Weedon, Michael N. (author)
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Wheeler, Eleanor (author)
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Wood, Andrew R. (author)
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Ferreira, Teresa (author)
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Weyant, Robert J. (author)
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Segre, Ayellet V. (author)
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Estrada, Karol (author)
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Liang, Liming (author)
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Nemesh, James (author)
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Park, Ju-Hyun (author)
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Gustafsson, Stefan (author)
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Kilpelaenen, Tuomas O. (author)
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Yang, Jian (author)
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Bouatia-Naji, Nabila (author)
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Esko, Tonu (author)
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Feitosa, Mary F. (author)
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Kutalik, Zoltan (author)
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Mangino, Massimo (author)
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Raychaudhuri, Soumya (author)
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Scherag, Andre (author)
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Smith, Albert Vernon (author)
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Welch, Ryan (author)
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Zhao, Jing Hua (author)
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Aben, Katja K. (author)
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Absher, Devin M. (author)
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Amin, Najaf (author)
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Dixon, Anna L. (author)
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Fisher, Eva (author)
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Glazer, Nicole L. (author)
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Goddard, Michael E. (author)
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Heard-Costa, Nancy L. (author)
-
Hoesel, Volker (author)
-
Hottenga, Jouke-Jan (author)
-
- Johansson, Åsa (author)
- Uppsala universitet,Institutionen för genetik och patologi
-
Johnson, Toby (author)
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Ketkar, Shamika (author)
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Lamina, Claudia (author)
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Li, Shengxu (author)
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Moffatt, Miriam F. (author)
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Myers, Richard H. (author)
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Narisu, Narisu (author)
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Perry, John R. B. (author)
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Peters, Marjolein J. (author)
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Preuss, Michael (author)
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Ripatti, Samuli (author)
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Rivadeneira, Fernando (author)
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Sandholt, Camilla (author)
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Scott, Laura J. (author)
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Timpson, Nicholas J. (author)
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Tyrer, Jonathan P. (author)
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van Wingerden, Sophie (author)
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Watanabe, Richard M. (author)
-
White, Charles C. (author)
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- Wiklund, Fredrik (author)
- Karolinska Institutet
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Barlassina, Christina (author)
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Chasman, Daniel I. (author)
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Cooper, Matthew N. (author)
-
- Jansson, John-Olov, 1954 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology
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Lawrence, Robert W. (author)
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Pellikka, Niina (author)
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Prokopenko, Inga (author)
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Shi, Jianxin (author)
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Thiering, Elisabeth (author)
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Alavere, Helene (author)
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Alibrandi, Maria T. S. (author)
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- Almgren, Peter (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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Arnold, Alice M. (author)
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Aspelund, Thor (author)
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Atwood, Larry D. (author)
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Balkau, Beverley (author)
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Balmforth, Anthony J. (author)
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Bennett, Amanda J. (author)
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Ben-Shlomo, Yoav (author)
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Bergman, Richard N. (author)
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Bergmann, Sven (author)
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Biebermann, Heike (author)
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Blakemore, Alexandra I. F. (author)
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Boes, Tanja (author)
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Bonnycastle, Lori L. (author)
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Bornstein, Stefan R. (author)
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Brown, Morris J. (author)
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Buchanan, Thomas A. (author)
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Busonero, Fabio (author)
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Campbell, Harry (author)
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Cappuccio, Francesco P. (author)
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Cavalcanti-Proenca, Christine (author)
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Chen, Yii-Der Ida (author)
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Chen, Chih-Mei (author)
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Chines, Peter S. (author)
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Clarke, Robert (author)
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Coin, Lachlan (author)
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Connell, John (author)
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Day, Ian N. M. (author)
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den Heijer, Martin (author)
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Duan, Jubao (author)
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Ebrahim, Shah (author)
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Elliott, Paul (author)
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Elosua, Roberto (author)
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Eiriksdottir, Gudny (author)
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Erdos, Michael R. (author)
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Eriksson, Johan G. (author)
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Facheris, Maurizio F. (author)
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Felix, Stephan B. (author)
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Fischer-Posovszky, Pamela (author)
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Folsom, Aaron R. (author)
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Friedrich, Nele (author)
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Freimer, Nelson B. (author)
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Fu, Mao (author)
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Gaget, Stefan (author)
-
Gejman, Pablo V. (author)
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Geus, Eco J. C. (author)
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Gieger, Christian (author)
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Gjesing, Anette P. (author)
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Goel, Anuj (author)
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Goyette, Philippe (author)
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Grallert, Harald (author)
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Graessler, Juergen (author)
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Greenawalt, Danielle M. (author)
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Groves, Christopher J. (author)
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Gudnason, Vilmundur (author)
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Guiducci, Candace (author)
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Hartikainen, Anna-Liisa (author)
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Hassanali, Neelam (author)
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Hall, Alistair S. (author)
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Havulinna, Aki S. (author)
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Hayward, Caroline (author)
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Heath, Andrew C. (author)
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Hengstenberg, Christian (author)
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Hicks, Andrew A. (author)
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Hinney, Anke (author)
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Hofman, Albert (author)
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Homuth, Georg (author)
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Hui, Jennie (author)
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- Igl, Wilmar (author)
- Uppsala universitet,Institutionen för genetik och patologi
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Iribarren, Carlos (author)
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Isomaa, Bo (author)
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Jacobs, Kevin B. (author)
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Jarick, Ivonne (author)
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Jewell, Elizabeth (author)
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John, Ulrich (author)
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Jorgensen, Torben (author)
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Jousilahti, Pekka (author)
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Jula, Antti (author)
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Kaakinen, Marika (author)
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Kajantie, Eero (author)
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Kaplan, Lee M. (author)
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Kathiresan, Sekar (author)
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Kettunen, Johannes (author)
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Kinnunen, Leena (author)
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Knowles, Joshua W. (author)
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Kolcic, Ivana (author)
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Koenig, Inke R. (author)
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Koskinen, Seppo (author)
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Kovacs, Peter (author)
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Kuusisto, Johanna (author)
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Kraft, Peter (author)
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Kvaloy, Kirsti (author)
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Laitinen, Jaana (author)
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Lantieri, Olivier (author)
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Lanzani, Chiara (author)
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Launer, Lenore J. (author)
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Lecoeur, Cecile (author)
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Lehtimaeki, Terho (author)
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Lettre, Guillaume (author)
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Liu, Jianjun (author)
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Lokki, Marja-Liisa (author)
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- Lorentzon, Mattias, 1970 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine
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Luben, Robert N. (author)
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Ludwig, Barbara (author)
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Manunta, Paolo (author)
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Marek, Diana (author)
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Marre, Michel (author)
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Martin, Nicholas G. (author)
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McArdle, Wendy L. (author)
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McCarthy, Anne (author)
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McKnight, Barbara (author)
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Meitinger, Thomas (author)
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- Melander, Olle (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
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Meyre, David (author)
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Midthjell, Kristian (author)
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Montgomery, Grant W. (author)
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Morken, Mario A. (author)
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Morris, Andrew P. (author)
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Mulic, Rosanda (author)
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Ngwa, Julius S. (author)
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Nelis, Mari (author)
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Neville, Matt J. (author)
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Nyholt, Dale R. (author)
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O'Donnell, Christopher J. (author)
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O'Rahilly, Stephen (author)
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Ong, Ken K. (author)
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Oostra, Ben (author)
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Pare, Guillaume (author)
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Parker, Alex N. (author)
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Perola, Markus (author)
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Pichler, Irene (author)
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- Pietilaeinen, Kirsi H. (author)
- Karolinska Institutet
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Platou, Carl G. P. (author)
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Polasek, Ozren (author)
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Pouta, Anneli (author)
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Rafelt, Suzanne (author)
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Raitakari, Olli (author)
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Rayner, Nigel W. (author)
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- Ridderstråle, Martin (author)
- Lund University,Lunds universitet,Diabetes - klinisk obesitasforskning,Forskargrupper vid Lunds universitet,Diabetes - Clinical Obesity,Lund University Research Groups
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Rief, Winfried (author)
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Ruokonen, Aimo (author)
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Robertson, Neil R. (author)
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Rzehak, Peter (author)
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Salomaa, Veikko (author)
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Sanders, Alan R. (author)
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Sandhu, Manjinder S. (author)
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Sanna, Serena (author)
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Saramies, Jouko (author)
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Savolainen, Markku J. (author)
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Scherag, Susann (author)
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Schipf, Sabine (author)
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Schreiber, Stefan (author)
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Schunkert, Heribert (author)
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Silander, Kaisa (author)
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Sinisalo, Juha (author)
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Siscovick, David S. (author)
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Smit, Jan H. (author)
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Soranzo, Nicole (author)
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Sovio, Ulla (author)
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Stephens, Jonathan (author)
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Surakka, Ida (author)
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Swift, Amy J. (author)
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Tammesoo, Mari-Liis (author)
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Tardif, Jean-Claude (author)
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Teder-Laving, Maris (author)
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Teslovich, Tanya M. (author)
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Thompson, John R. (author)
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Thomson, Brian (author)
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Toenjes, Anke (author)
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Tuomi, Tiinamaija (author)
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van Meurs, Joyce B. J. (author)
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van Ommen, Gert-Jan (author)
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Vatin, Vincent (author)
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Viikari, Jorma (author)
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Visvikis-Siest, Sophie (author)
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Vitart, Veronique (author)
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Vogel, Carla I. G. (author)
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Voight, Benjamin F. (author)
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Waite, Lindsay L. (author)
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Wallaschofski, Henri (author)
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Walters, G. Bragi (author)
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Widen, Elisabeth (author)
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Wiegand, Susanna (author)
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Wild, Sarah H. (author)
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Willemsen, Gonneke (author)
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Witte, Daniel R. (author)
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Witteman, Jacqueline C. (author)
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Xu, Jianfeng (author)
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Zhang, Qunyuan (author)
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Zgaga, Lina (author)
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Ziegler, Andreas (author)
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Zitting, Paavo (author)
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Beilby, John P. (author)
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Farooqi, I. Sadaf (author)
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Hebebrand, Johannes (author)
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Huikuri, Heikki V. (author)
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James, Alan L. (author)
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Kaehoenen, Mika (author)
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Levinson, Douglas F. (author)
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Macciardi, Fabio (author)
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Nieminen, Markku S. (author)
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- Ohlsson, Claes, 1965 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine
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Palmer, Lyle J. (author)
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Ridker, Paul M. (author)
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Stumvoll, Michael (author)
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Beckmann, Jacques S. (author)
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Boeing, Heiner (author)
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Boerwinkle, Eric (author)
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Boomsma, Dorret I. (author)
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Caulfield, Mark J. (author)
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Chanock, Stephen J. (author)
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Collins, Francis S. (author)
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Cupples, L. Adrienne (author)
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Smith, George Davey (author)
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Erdmann, Jeanette (author)
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Froguel, Philippe (author)
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- Greonberg, Henrik (author)
- Karolinska Institutet
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- Gyllensten, Ulf (author)
- Uppsala universitet,Institutionen för genetik och patologi
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Hall, Per (author)
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Hansen, Torben (author)
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Harris, Tamara B. (author)
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Hattersley, Andrew T. (author)
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Hayes, Richard B. (author)
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Heinrich, Joachim (author)
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Hu, Frank B. (author)
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Hveem, Kristian (author)
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Illig, Thomas (author)
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Jarvelin, Marjo-Riitta (author)
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Kaprio, Jaakko (author)
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Karpe, Fredrik (author)
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Khaw, Kay-Tee (author)
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Kiemeney, Lambertus A. (author)
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Krude, Heiko (author)
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Laakso, Markku (author)
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Lawlor, Debbie A. (author)
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Metspalu, Andres (author)
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Munroe, Patricia B. (author)
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Ouwehand, Willem H. (author)
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Pedersen, Oluf (author)
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Penninx, Brenda W. (author)
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Peters, Annette (author)
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Pramstaller, Peter P. (author)
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Quertermous, Thomas (author)
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Reinehr, Thomas (author)
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Rissanen, Aila (author)
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Rudan, Igor (author)
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Samani, Nilesh J. (author)
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Schwarz, Peter E. H. (author)
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Shuldiner, Alan R. (author)
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Spector, Timothy D. (author)
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Tuomilehto, Jaakko (author)
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Uda, Manuela (author)
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Uitterlinden, Andre (author)
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Valle, Timo T. (author)
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Wabitsch, Martin (author)
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Waeber, Gerard (author)
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Wareham, Nicholas J. (author)
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Watkins, Hugh (author)
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Wilson, James F. (author)
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Wright, Alan F. (author)
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Zillikens, M. Carola (author)
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Chatterjee, Nilanjan (author)
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McCarroll, Steven A. (author)
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Purcell, Shaun (author)
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Schadt, Eric E. (author)
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Visscher, Peter M. (author)
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Assimes, Themistocles L. (author)
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Borecki, Ingrid B. (author)
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Deloukas, Panos (author)
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Fox, Caroline S. (author)
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- Groop, Leif (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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Haritunians, Talin (author)
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Hunter, David J. (author)
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Kaplan, Robert C. (author)
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Mohlke, Karen L. (author)
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O'Connell, Jeffrey R. (author)
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Peltonen, Leena (author)
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Schlessinger, David (author)
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Strachan, David P. (author)
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van Duijn, Cornelia M. (author)
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Wichmann, H-Erich (author)
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Frayling, Timothy M. (author)
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Thorsteinsdottir, Unnur (author)
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Abecasis, Goncalo R. (author)
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Barroso, Ines (author)
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Boehnke, Michael (author)
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Stefansson, Kari (author)
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North, Kari E. (author)
-
McCarthy, Mark I. (author)
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Hirschhorn, Joel N. (author)
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- Ingelsson, Erik (author)
- Karolinska Institutet
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Loos, Ruth J. F. (author)
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Gräßler, Jürgen (author)
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(creator_code:org_t)
- 2010-10-10
- 2010
- English.
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 42:11, s. 937-948
- Related links:
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https://europepmc.or...
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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https://gup.ub.gu.se...
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http://kipublication...
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Abstract
Subject headings
Close
- Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and ~2.8 million SNPs in up to 123,865 individuals with targeted follow up of 42 SNPs in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci and identified 18 new loci associated with body mass index (P < 5 × 10−8), one of which includes a copy number variant near GPRC5B. Some loci (at MC4R, POMC, SH2B1 and BDNF) map near key hypothalamic regulators of energy balance, and one of these loci is near GIPR, an incretin receptor. Furthermore, genes in other newly associated loci may provide new insights into human body weight regulation.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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Gieger, Christia ...
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Gjesing, Anette ...
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Goel, Anuj
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Grallert, Harald
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Graessler, Juerg ...
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Greenawalt, Dani ...
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Gudnason, Vilmun ...
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Guiducci, Candac ...
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John, Ulrich
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Polasek, Ozren
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Rief, Winfried
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Gräßler, Jürgen
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
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and Health Sciences
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and Nutrition and Di ...
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and Basic Medicine
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- Articles in the publication
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Nature Genetics
- By the university
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Uppsala University
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Lund University
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University of Gothenburg
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Karolinska Institutet