Sökning: (WFRF:(Bujie Z.)) > Analyses of pig gen...
Fältnamn | Indikatorer | Metadata |
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000 | 07887naa a2202005 4500 | |
001 | oai:DiVA.org:uu-185085 | |
003 | SwePub | |
008 | 121120s2012 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1850852 URI |
024 | 7 | a https://doi.org/10.1038/nature116222 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Groenen, M. A.4 aut |
245 | 1 0 | a Analyses of pig genomes provide insight into porcine demography and evolution |
264 | c 2012-11-14 | |
264 | 1 | b Springer Science and Business Media LLC,c 2012 |
338 | a print2 rdacarrier | |
520 | a For 10,000 years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars approximately 1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model. | |
650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng |
650 | 7 | a LANTBRUKSVETENSKAPERx Husdjursvetenskap0 (SwePub)4022 hsv//swe |
650 | 7 | a AGRICULTURAL SCIENCESx Animal and Dairy Sience0 (SwePub)4022 hsv//eng |
653 | a Biology with specialization in Evolutionary Genetics | |
653 | a Biologi med inriktning mot evolutionär genetik | |
653 | a Biologi med inriktning mot evolutionär funktionsgenomik | |
653 | a Biology with specialization in Evolutionary Functional Genomics | |
700 | 1 | a Archibald, A. L.4 aut |
700 | 1 | a Uenishi, H.4 aut |
700 | 1 | a Tuggle, C. K.4 aut |
700 | 1 | a Takeuchi, Y.4 aut |
700 | 1 | a Rothschild, M. F.4 aut |
700 | 1 | a Rogel-Gaillard, C.4 aut |
700 | 1 | a Park, C.4 aut |
700 | 1 | a Milan, D.4 aut |
700 | 1 | a Megens, H. J.4 aut |
700 | 1 | a Li, S.4 aut |
700 | 1 | a Larkin, D. M.4 aut |
700 | 1 | a Kim, H.4 aut |
700 | 1 | a Frantz, L. A.4 aut |
700 | 1 | a Caccamo, M.4 aut |
700 | 1 | a Ahn, H.4 aut |
700 | 1 | a Aken, B. L.4 aut |
700 | 1 | a Anselmo, A.4 aut |
700 | 1 | a Anthon, C.4 aut |
700 | 1 | a Auvil, L.4 aut |
700 | 1 | a Badaoui, B.4 aut |
700 | 1 | a Beattie, C. W.4 aut |
700 | 1 | a Bendixen, C.4 aut |
700 | 1 | a Berman, D.4 aut |
700 | 1 | a Blecha, F.4 aut |
700 | 1 | a Blomberg, Jonasu Uppsala universitet,Klinisk virologi4 aut0 (Swepub:uu)jonablom |
700 | 1 | a Bolund, L.4 aut |
700 | 1 | a Bosse, M.4 aut |
700 | 1 | a Botti, S.4 aut |
700 | 1 | a Bujie, Z.4 aut |
700 | 1 | a Byström, M.4 aut |
700 | 1 | a Capitanu, B.4 aut |
700 | 1 | a Carvalho-Silva, D.4 aut |
700 | 1 | a Chardon, P.4 aut |
700 | 1 | a Chen, C.4 aut |
700 | 1 | a Cheng, R.4 aut |
700 | 1 | a Choi, S. H.4 aut |
700 | 1 | a Chow, W.4 aut |
700 | 1 | a Clark, R. C.4 aut |
700 | 1 | a Clee, C.4 aut |
700 | 1 | a Crooijmans, R. P.4 aut |
700 | 1 | a Dawson, H. D.4 aut |
700 | 1 | a Dehais, P.4 aut |
700 | 1 | a De Sapio, F.4 aut |
700 | 1 | a Dibbits, B.4 aut |
700 | 1 | a Drou, N.4 aut |
700 | 1 | a Du, Z. Q.4 aut |
700 | 1 | a Eversole, K.4 aut |
700 | 1 | a Fadista, J.4 aut |
700 | 1 | a Fairley, S.4 aut |
700 | 1 | a Faraut, T.4 aut |
700 | 1 | a Faulkner, G. J.4 aut |
700 | 1 | a Fowler, K. E.4 aut |
700 | 1 | a Fredholm, M.4 aut |
700 | 1 | a Fritz, E.4 aut |
700 | 1 | a Gilbert, J. G.4 aut |
700 | 1 | a Giuffra, E.4 aut |
700 | 1 | a Gorodkin, J.4 aut |
700 | 1 | a Griffin, D. K.4 aut |
700 | 1 | a Harrow, J. L.4 aut |
700 | 1 | a Hayward, Alexanderu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)aleha347 |
700 | 1 | a Howe, K.4 aut |
700 | 1 | a Hu, Z. L.4 aut |
700 | 1 | a Humphray, S. J.4 aut |
700 | 1 | a Hunt, T.4 aut |
700 | 1 | a Hornshoj, H.4 aut |
700 | 1 | a Jeon, J. T.4 aut |
700 | 1 | a Jern, Patricu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)patrjern |
700 | 1 | a Jones, M.4 aut |
700 | 1 | a Jurka, J.4 aut |
700 | 1 | a Kanamori, H.4 aut |
700 | 1 | a Kapetanovic, R.4 aut |
700 | 1 | a Kim, J.4 aut |
700 | 1 | a Kim, J. H.4 aut |
700 | 1 | a Kim, K. W.4 aut |
700 | 1 | a Kim, T. H.4 aut |
700 | 1 | a Larson, G.4 aut |
700 | 1 | a Lee, K.4 aut |
700 | 1 | a Lee, K. T.4 aut |
700 | 1 | a Leggett, R.4 aut |
700 | 1 | a Lewin, H. A.4 aut |
700 | 1 | a Li, Y.4 aut |
700 | 1 | a Liu, W.4 aut |
700 | 1 | a Loveland, J. E.4 aut |
700 | 1 | a Lu, Y.4 aut |
700 | 1 | a Lunney, J. K.4 aut |
700 | 1 | a Ma, J.4 aut |
700 | 1 | a Madsen, O.4 aut |
700 | 1 | a Mann, K.4 aut |
700 | 1 | a Matthews, L.4 aut |
700 | 1 | a McLaren, S.4 aut |
700 | 1 | a Morozumi, T.4 aut |
700 | 1 | a Murtaugh, M. P.4 aut |
700 | 1 | a Narayan, J.4 aut |
700 | 1 | a Nguyen, D. T.4 aut |
700 | 1 | a Ni, P.4 aut |
700 | 1 | a Oh, S. J.4 aut |
700 | 1 | a Onteru, S.4 aut |
700 | 1 | a Panitz, F.4 aut |
700 | 1 | a Park, E. W.4 aut |
700 | 1 | a Park, H. S.4 aut |
700 | 1 | a Pascal, G.4 aut |
700 | 1 | a Paudel, Y.4 aut |
700 | 1 | a Perez-Enciso, M.4 aut |
700 | 1 | a Ramirez-Gonzalez, R.4 aut |
700 | 1 | a Reecy, J. M.4 aut |
700 | 1 | a Rodriguez-Zas, S.4 aut |
700 | 1 | a Rohrer, G. A.4 aut |
700 | 1 | a Rund, L.4 aut |
700 | 1 | a Sang, Y.4 aut |
700 | 1 | a Schachtschneider, K.4 aut |
700 | 1 | a Schraiber, J. G.4 aut |
700 | 1 | a Schwartz, J.4 aut |
700 | 1 | a Scobie, L.4 aut |
700 | 1 | a Scott, C.4 aut |
700 | 1 | a Searle, S.4 aut |
700 | 1 | a Servin, B.4 aut |
700 | 1 | a Southey, B. R.4 aut |
700 | 1 | a Sperber, Göranu Uppsala universitet,Fysiologi4 aut0 (Swepub:uu)gsp26613 |
700 | 1 | a Stadler, P.4 aut |
700 | 1 | a Sweedler, J. V.4 aut |
700 | 1 | a Tafer, H.4 aut |
700 | 1 | a Thomsen, B.4 aut |
700 | 1 | a Wali, R.4 aut |
700 | 1 | a Wang, J.4 aut |
700 | 1 | a White, S.4 aut |
700 | 1 | a Xu, X.4 aut |
700 | 1 | a Yerle, M.4 aut |
700 | 1 | a Zhang, G.4 aut |
700 | 1 | a Zhang, J.4 aut |
700 | 1 | a Zhao, S.4 aut |
700 | 1 | a Rogers, J.4 aut |
700 | 1 | a Churcher, C.4 aut |
700 | 1 | a Schook, L. B.4 aut |
710 | 2 | a Uppsala universitetb Klinisk virologi4 org |
773 | 0 | t Natured : Springer Science and Business Media LLCg 491:7424, s. 393-398q 491:7424<393-398x 0028-0836x 1476-4687 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=23151582 |
856 | 4 | u https://www.nature.com/articles/nature11622.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-185085 |
856 | 4 8 | u https://doi.org/10.1038/nature11622 |
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