Search: (WFRF:(Chernogubova Ekaterina)) > (2005-2009) >
Fältnamn | Indikatorer | Metadata |
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000 | 02225nam a2200337 4500 | |
001 | oai:DiVA.org:su-549 | |
003 | SwePub | |
008 | 050526s2005 | |||||||||||000 ||eng| | |
020 | a 9171550968q print | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-5492 URI |
040 | a (SwePub)su | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a vet2 swepub-contenttype |
072 | 7 | a dok2 swepub-publicationtype |
100 | 1 | a Chernogubova, Ekaterina,d 1967-u Stockholms universitet,Wenner-Grens institut4 aut |
245 | 1 0 | a Adrenergic stimulation of glucose uptake in brown adipocytes |
264 | 1 | a Stockholm :b Wenner-Grens institut för experimentell biologi,c 2005 |
300 | a 129 s. | |
338 | a electronic2 rdacarrier | |
520 | a The aim of this study was to investigate adrenergically stimulated glucose uptake in brown adipose tissue (BAT) with the focus on receptor subtypes and intracellular signalling pathways. As a model system, we used primary cultured brown adipocytes.Adrenergic stimulation of glucose uptake occurs via β3-AR in wild type cells and β1-/α1-ARs in β3-KO cells, includes activation of adenylyl cyclase and cAMP formation, activation of PKA, PI3K, PKC and AMPK (Paper I, II, III). Interestingly, UCP1 activity is not required for the AMPK function in brown adipocytes (Paper III). Long-term adrenergic stimulation of glucose uptake induces an increase in GLUT1 mRNA and protein levels stimulating GLUT1 translocation to the plasma membrane (Paper IV). | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng |
653 | a Physiology | |
653 | a Fysiologi | |
700 | 1 | a Bengtsson, Toreu Stockholms universitet,Wenner-Grens institut4 ths |
700 | 1 | a Cannon, Barbarau Stockholms universitet,Wenner-Grens institut4 ths |
700 | 1 | a Cushman, Samuelu NIDDK, NIH4 opn |
710 | 2 | a Stockholms universitetb Wenner-Grens institut4 org |
856 | 4 | u https://su.diva-portal.org/smash/get/diva2:195342/FULLTEXT01.pdfx primaryx Raw objecty fulltext |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-549 |
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