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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002225nam a2200337 4500
001oai:DiVA.org:su-549
003SwePub
008050526s2005 | |||||||||||000 ||eng|
020 a 9171550968q print
024a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-5492 URI
040 a (SwePub)su
041 a engb eng
042 9 SwePub
072 7a vet2 swepub-contenttype
072 7a dok2 swepub-publicationtype
100a Chernogubova, Ekaterina,d 1967-u Stockholms universitet,Wenner-Grens institut4 aut
2451 0a Adrenergic stimulation of glucose uptake in brown adipocytes
264 1a Stockholm :b Wenner-Grens institut för experimentell biologi,c 2005
300 a 129 s.
338 a electronic2 rdacarrier
520 a The aim of this study was to investigate adrenergically stimulated glucose uptake in brown adipose tissue (BAT) with the focus on receptor subtypes and intracellular signalling pathways. As a model system, we used primary cultured brown adipocytes.Adrenergic stimulation of glucose uptake occurs via β3-AR in wild type cells and β1-/α1-ARs in β3-KO cells, includes activation of adenylyl cyclase and cAMP formation, activation of PKA, PI3K, PKC and AMPK (Paper I, II, III). Interestingly, UCP1 activity is not required for the AMPK function in brown adipocytes (Paper III). Long-term adrenergic stimulation of glucose uptake induces an increase in GLUT1 mRNA and protein levels stimulating GLUT1 translocation to the plasma membrane (Paper IV).
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng
653 a Physiology
653 a Fysiologi
700a Bengtsson, Toreu Stockholms universitet,Wenner-Grens institut4 ths
700a Cannon, Barbarau Stockholms universitet,Wenner-Grens institut4 ths
700a Cushman, Samuelu NIDDK, NIH4 opn
710a Stockholms universitetb Wenner-Grens institut4 org
856u https://su.diva-portal.org/smash/get/diva2:195342/FULLTEXT01.pdfx primaryx Raw objecty fulltext
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-549

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Chernogubova, Ek ...
Bengtsson, Tore
Cannon, Barbara
Cushman, Samuel
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
and Physiology
By the university
Stockholm University

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