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Sökning: (WFRF:(Getchell Marya)) conttype:(refereed) > Variation in the ca...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003666naa a2200565 4500
001oai:DiVA.org:uu-137847
003SwePub
008101216s2010 | |||||||||||000 ||eng|
009oai:DiVA.org:su-29893
009oai:prod.swepub.kib.ki.se:119904754
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1378472 URI
0247 a https://doi.org/10.1097/YPG.0b013e32833511e42 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-298932 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1199047542 URI
040 a (SwePub)uud (SwePub)sud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a DeYoung, Colin G.4 aut
2451 0a Variation in the catechol-O-methyltransferase Val(158)Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents
264 1c 2010
338 a print2 rdacarrier
520 a Objective Variation in the catechol-O-methyltransferase gene (COMT) has been associated with antisocial behavior in populations with attention deficit/hyperactivity disorder (ADHD). This study examined whether COMT would predict antisocial behavior in a sample with high levels of behavior problems, not necessarily ADHD. In addition, because previous research suggests that COMT may be associated with ADHD in males, association between COMT and ADHD symptoms was examined. Method This study tested whether variation in three polymorphisms of the COMT gene was predictive of symptoms of conduct disorder and ADHD, in a sample of 174 incarcerated Russian adolescent male delinquents. Results The Val allele of the Val(158)Met polymorphism was significantly associated with conduct disorder diagnosis and symptoms, whereas the Met allele was associated with ADHD symptoms. Conclusion The Val(158)Met polymorphism of the COMT gene shows a complex relation to behavior problems, influencing conduct disorder and ADHD symptoms in opposite directions in a high-risk population. Psychiatr Genet 20:20-24 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
650 7a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe
650 7a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng
653 a antisocial behavior
653 a attention deficit/hyperactivity disorder
653 a catechol-O-methyltransferase
653 a conduct disorder
653 a genetics
653 a MEDICINE
653 a MEDICIN
653 a Psychology
653 a Psykologi
7001 a Getchell, Marya4 aut
7001 a Koposov, Roman A.4 aut
7001 a Yrigollen, Carolyn M.4 aut
7001 a Haeffel, Gerald J.4 aut
7001 a af Klinteberg, Brittu Karolinska Institutet,Stockholms universitet,Centrum för forskning om ojämlikhet i hälsa (CHESS)4 aut0 (Swepub:su)bklin
7001 a Oreland, Larsu Uppsala universitet,Institutionen för neurovetenskap4 aut0 (Swepub:uu)larsore
7001 a Ruchkin, Vladislav V.u Karolinska Institutet4 aut0 (Swepub:uu)vlaru690
7001 a Pakstis, Andrew J.4 aut
7001 a Grigorenko, Elena L.4 aut
7102 a Stockholms universitetb Centrum för forskning om ojämlikhet i hälsa (CHESS)4 org
7730 t Psychiatric Geneticsg 20:1, s. 20-24q 20:1<20-24x 0955-8829x 1473-5873
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-137847
8564 8u https://doi.org/10.1097/YPG.0b013e32833511e4
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-29893
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:119904754

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