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Sökning: (WFRF:(Relton Caroline)) pers:(Sesso Howard D) > (2017) > Circulating concent...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008563naa a2201105 4500
001oai:DiVA.org:umu-137053
003SwePub
008170628s2017 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:3d99fcd7-2e40-4a10-8263-f211cc9e06de
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1370532 URI
0247 a https://doi.org/10.3945/ajcn.116.1512412 DOI
0247 a https://lup.lub.lu.se/record/3d99fcd7-2e40-4a10-8263-f211cc9e06de2 URI
040 a (SwePub)umud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Midttun, Oivindu Bevital AS4 aut
2451 0a Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations
264 1b AMER SOC NUTRITION-ASN,c 2017
338 a print2 rdacarrier
520 a Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the variation across laboratories, which complicates a comparison of results from different studies. Objective: We robustly and comprehensively assessed differences in biomarkers that are related to vitamin status across geographic regions. Design: The trial was a cross-sectional study in which we investigated 38 biomarkers that are related to vitamin status and one-carbon and tryptophan metabolism in serum and plasma from 5314 healthy control subjects representing 20 cohorts recruited from the United States, Nordic countries, Asia, and Australia, participating in the Lung Cancer Cohort Consortium. All samples were analyzed in a centralized laboratory. Results: Circulating concentrations of riboflavin, pyridoxal 5'-phosphate, folate, vitamin B-12, all-trans retinol, 25-hydroxyvitamin D, and a-tocopherol as well as combined vitamin scores that were based on these nutrients showed that the general B-vitamin concentration was highest in the United States and that the B vitamins and lipid soluble vitamins were low in Asians. Conversely, circulating concentrations of metabolites that are inversely related to B vitamins involved in the one-carbon and kynurenine pathways were high in Asians. The high B-vitamin concentration in the United States appears to be driven mainly by multivitamin-supplement users. Conclusions: The observed differences likely reflect the variation in intake of vitamins and, in particular, the widespread multivitamin-supplement use in the United States. The results provide valuable information about the differences in biomarker concentrations in populations across continents.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
653 a biomarker
653 a Lung Cancer Cohort Consortium
653 a one-carbon metabolism
653 a tryptophan metabolism
653 a tamin status
653 a Biomarker
653 a Lung Cancer Cohort Consortium
653 a One-carbon metabolism
653 a Tryptophan metabolism
653 a Vitamin status
7001 a Theofylaktopoulou, Despoinau University of Bergen4 aut
7001 a McCann, Adrianu Bevital AS4 aut
7001 a Fanidi, Anouaru International Agency for Research on Cancer, World Health Organization4 aut
7001 a Muller, David C.u International Agency for Research on Cancer, World Health Organization,Imperial College London4 aut
7001 a Meyer, Klausu Bevital AS4 aut
7001 a Ulvik, Arveu Bevital AS4 aut
7001 a Zheng, Weiu Vanderbilt University Medical Center4 aut
7001 a Shu, Xiao-Ouu Vanderbilt University Medical Center4 aut
7001 a Xiang, Yong-Bingu Shanghai Cancer Institute4 aut
7001 a Prentice, Rossu Fred Hutchinson Cancer Research Center4 aut
7001 a Thomson, Cynthia A.u University of Arizona4 aut
7001 a Pettinger, Maryu Fred Hutchinson Cancer Research Center4 aut
7001 a Giles, Graham G.u University of Melbourne,National Cancer Institute, USA4 aut
7001 a Hodge, Allisonu University of Melbourne4 aut
7001 a Cai, Qiuyinu Vanderbilt University4 aut
7001 a Blot, William J.u Vanderbilt University Medical Center4 aut
7001 a Wu, Jieu Vanderbilt University Medical Center4 aut
7001 a Johansson, Mikaelu Umeå University,Brigham and Women's Hospital / Harvard Medical School4 aut
7001 a Hultdin, Johanu Umeå University,Umeå universitet,Klinisk kemi4 aut0 (Swepub:umu)johu0007
7001 a Grankvist, Kjellu Umeå University,Umeå universitet,Klinisk kemi4 aut0 (Swepub:umu)kjgr0002
7001 a Stevens, Victoria L.u American Cancer Society4 aut
7001 a McCullough, Marjorie L.u American Cancer Society,University of Pittsburgh Cancer Institute4 aut
7001 a Weinstein, Stephanie J.u National Cancer Institute, USA4 aut
7001 a Albanes, Demetriusu National Cancer Institute, USA4 aut
7001 a Langhammer, Arnulfu Norwegian University of Science and Technology4 aut
7001 a Hveem, Kristianu Norwegian University of Science and Technology4 aut
7001 a Naess, Marit4 aut
7001 a Sesso, Howard D.u Harvard University,Brigham and Women's Hospital / Harvard Medical School4 aut
7001 a Gaziano, J. Michael4 aut
7001 a Buring, Julie E.u Brigham and Women's Hospital / Harvard Medical School,Harvard University4 aut
7001 a Lee, I-Minu Harvard University,Brigham and Women's Hospital / Harvard Medical School4 aut
7001 a Severi, Gianlucau Human Genetics Foundation (HuGeF),University of Paris-Saclay4 aut
7001 a Zhang, Xuehongu Brigham and Women's Hospital / Harvard Medical School4 aut
7001 a Han, Jialiu Harvard University4 aut
7001 a Stampfer, Meir J.u Brigham and Women's Hospital / Harvard Medical School,Harvard University4 aut
7001 a Smith-Warner, Stephanie A.u Harvard University4 aut
7001 a Zeleniuch-Jacquotte, Anneu New York University4 aut
7001 a le Marchand, Loicu University of Hawaii at Manoa4 aut
7001 a Yuan, Jian-Minu University of Pittsburgh Cancer Institute,University of Pittsburgh4 aut
7001 a Butler, Lesley M.4 aut
7001 a Koh, Woon-Puayu Duke–NUS Medical School4 aut
7001 a Wang, Renweiu University of Pittsburgh Cancer Institute4 aut
7001 a Gao, Yu-Tangu Shanghai Jiao Tong University4 aut
7001 a Ericson, Ulrikau Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)medf-upe
7001 a Sonestedt, Emilyu Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Nutritionsepidemiologi,Diabetes - Cardiovascular Disease,Lund University Research Groups,Nutrition Epidemiology4 aut0 (Swepub:lu)medf-eso
7001 a Ziegler, Regina G.4 aut
7001 a Freedman, Neal D.u National Cancer Institute, USA4 aut
7001 a Visvanathan, Kalau Johns Hopkins Bloomberg School of Public Health4 aut
7001 a Jones, Miranda R.u Johns Hopkins Bloomberg School of Public Health4 aut
7001 a Relton, Carolineu University of Newcastle upon Tyne,University of Bristol4 aut
7001 a Brennan, Paulu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Johansson, Mattiasu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Ueland, Per M.u University of Bergen,Haukeland University Hospital4 aut
7001 a Næss, Maritu Norwegian University of Science and Technology4 aut
7102 a Bevital ASb University of Bergen4 org
7730 t American Journal of Clinical Nutritiond : AMER SOC NUTRITION-ASNg 105:6, s. 1314-1326q 105:6<1314-1326x 0002-9165x 1938-3207
8564 u https://academic.oup.com/ajcn/article-pdf/105/6/1314/23801126/ajcn151241.pdf
8564 u http://dx.doi.org/10.3945/ajcn.116.151241x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-137053
8564 8u https://doi.org/10.3945/ajcn.116.151241
8564 8u https://lup.lub.lu.se/record/3d99fcd7-2e40-4a10-8263-f211cc9e06de

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