Research needs in allergy: an EAACI position paper, in collaboration with EFA.

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Fältnamn	Indikatorer	Metadata
000		10244naa a2202041 4500
001		oai:gup.ub.gu.se/172635
003		SwePub
008		240528s2012 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:223121771
024	7	a https://gup.ub.gu.se/publication/1726352 URI
024	7	a https://doi.org/10.1186/2045-7022-2-212 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:2231217712 URI
040		a (SwePub)gud (SwePub)ki
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Papadopoulos, Nikolaos G4 aut
245	1 0	a Research needs in allergy: an EAACI position paper, in collaboration with EFA.
264		c 2012-11-02
264	1	b Wiley,c 2012
338		a electronic2 rdacarrier
520		a ABSTRACT: In less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting the budgets of public health systems. More disturbingly, its prevalence and impact are on the rise, a development that has been associated with environmental and lifestyle changes accompanying the continuous process of urbanization and globalization. Therefore, there is an urgent need to prioritize and concert research efforts in the field of allergy, in order to achieve sustainable results on prevention, diagnosis and treatment of this most prevalent chronic disease of the 21st century.The European Academy of Allergy and Clinical Immunology (EAACI) is the leading professional organization in the field of allergy, promoting excellence in clinical care, education, training and basic and translational research, all with the ultimate goal of improving the health of allergic patients. The European Federation of Allergy and Airways Diseases Patients' Associations (EFA) is a non-profit network of allergy, asthma and Chronic Obstructive Pulmonary Disorder (COPD) patients' organizations. In support of their missions, the present EAACI Position Paper, in collaboration with EFA, highlights the most important research needs in the field of allergy to serve as key recommendations for future research funding at the national and European levels.Although allergies may involve almost every organ of the body and an array of diverse external factors act as triggers, there are several common themes that need to be prioritized in research efforts. As in many other chronic diseases, effective prevention, curative treatment and accurate, rapid diagnosis represent major unmet needs. Detailed phenotyping/endotyping stands out as widely required in order to arrange or re-categorize clinical syndromes into more coherent, uniform and treatment-responsive groups. Research efforts to unveil the basic pathophysiologic pathways and mechanisms, thus leading to the comprehension and resolution of the pathophysiologic complexity of allergies will allow for the design of novel patient-oriented diagnostic and treatment protocols. Several allergic diseases require well-controlled epidemiological description and surveillance, using disease registries, pharmacoeconomic evaluation, as well as large biobanks. Additionally, there is a need for extensive studies to bring promising new biotechnological innovations, such as biological agents, vaccines of modified allergen molecules and engineered components for allergy diagnosis, closer to clinical practice. Finally, particular attention should be paid to the difficult-to-manage, precarious and costly severe disease forms and/or exacerbations. Nonetheless, currently arising treatments, mainly in the fields of immunotherapy and biologicals, hold great promise for targeted and causal management of allergic conditions. Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng
653		a Allergy
653		a Allergic diseases
653		a Policy
653		a Research needs
653		a Research funding
653		a Europe
700	1	a Agache, Ioana4 aut
700	1	a Bavbek, Sevim4 aut
700	1	a Bilo, Beatrice M4 aut
700	1	a Braido, Fulvio4 aut
700	1	a Cardona, Victoria4 aut
700	1	a Custovic, Adnan4 aut
700	1	a Demonchy, Jan4 aut
700	1	a Demoly, Pascal4 aut
700	1	a Eigenmann, Philippe4 aut
700	1	a Gayraud, Jacques4 aut
700	1	a Grattan, Clive4 aut
700	1	a Heffler, Enrico4 aut
700	1	a Hellings, Peter W4 aut
700	1	a Jutel, Marek4 aut
700	1	a Knol, Edward4 aut
700	1	a Lötvall, Jan,d 1956u Gothenburg University,Göteborgs universitet,Krefting Research Centre4 aut0 (Swepub:gu)xlotja
700	1	a Muraro, Antonella4 aut
700	1	a Poulsen, Lars K4 aut
700	1	a Roberts, Graham4 aut
700	1	a Schmid-Grendelmeier, Peter4 aut
700	1	a Skevaki, Chrysanthi4 aut
700	1	a Triggiani, Massimo4 aut
700	1	a Vanree, Ronald4 aut
700	1	a Werfel, Thomas4 aut
700	1	a Flood, Breda4 aut
700	1	a Palkonen, Susanna4 aut
700	1	a Savli, Roberta4 aut
700	1	a Allegri, Pia4 aut
700	1	a Annesi-Maesano, Isabella4 aut
700	1	a Annunziato, Francesco4 aut
700	1	a Antolin-Amerigo, Dario4 aut
700	1	a Apfelbacher, Christian4 aut
700	1	a Blanca, Miguel4 aut
700	1	a Bogacka, Ewa4 aut
700	1	a Bonadonna, Patrizia4 aut
700	1	a Bonini, Matteo4 aut
700	1	a Boyman, Onur4 aut
700	1	a Brockow, Knut4 aut
700	1	a Burney, Peter4 aut
700	1	a Buters, Jeroen4 aut
700	1	a Butiene, Indre4 aut
700	1	a Calderon, Moises4 aut
700	1	a Cardell, Lars Olafu Karolinska Institutet4 aut
700	1	a Caubet, Jean-Christoph4 aut
700	1	a Celenk, Sevcan4 aut
700	1	a Cichocka-Jarosz, Ewa4 aut
700	1	a Cingi, Cemal4 aut
700	1	a Couto, Mariana4 aut
700	1	a Dejong, Nicolette4 aut
700	1	a Del Giacco, Stefano4 aut
700	1	a Douladiris, Nikolaos4 aut
700	1	a Fassio, Filippo4 aut
700	1	a Fauquert, Jean-Luc4 aut
700	1	a Fernandez, Javier4 aut
700	1	a Rivas, Montserrat Fernandez4 aut
700	1	a Ferrer, Marta4 aut
700	1	a Flohr, Carsten4 aut
700	1	a Gardner, James4 aut
700	1	a Genuneit, Jon4 aut
700	1	a Gevaert, Philippe4 aut
700	1	a Groblewska, Anna4 aut
700	1	a Hamelmann, Eckard4 aut
700	1	a Hoffmann, Hans Jürgen4 aut
700	1	a Hoffmann-Sommergruber, Karin4 aut
700	1	a Hovhannisyan, Lilit4 aut
700	1	a Hox, Valérie4 aut
700	1	a Jahnsen, Frode L4 aut
700	1	a Kalayci, Omer4 aut
700	1	a Kalpaklioglu, Ayse Füsun4 aut
700	1	a Kleine-Tebbe, Jörg4 aut
700	1	a Konstantinou, George4 aut
700	1	a Kurowski, Marcin4 aut
700	1	a Lau, Susanne4 aut
700	1	a Lauener, Roger4 aut
700	1	a Lauerma, Antti4 aut
700	1	a Logan, Kirsty4 aut
700	1	a Magnan, Antoine4 aut
700	1	a Makowska, Joanna4 aut
700	1	a Makrinioti, Heidi4 aut
700	1	a Mangina, Paraskevi4 aut
700	1	a Manole, Felicia4 aut
700	1	a Mari, Adriano4 aut
700	1	a Mazon, Angel4 aut
700	1	a Mills, Clare4 aut
700	1	a Mingomataj, Ervinç4 aut
700	1	a Niggemann, Bodo4 aut
700	1	a Nilsson, Gunnar4 aut
700	1	a Ollert, Markus4 aut
700	1	a O'Mahony, Liam4 aut
700	1	a O'Neil, Serena,d 19814 aut
700	1	a Pala, Gianni4 aut
700	1	a Papi, Alberto4 aut
700	1	a Passalacqua, Gianni4 aut
700	1	a Perkin, Michael4 aut
700	1	a Pfaar, Oliver4 aut
700	1	a Pitsios, Constantinos4 aut
700	1	a Quirce, Santiago4 aut
700	1	a Raap, Ulrike4 aut
700	1	a Raulf-Heimsoth, Monika4 aut
700	1	a Rhyner, Claudio4 aut
700	1	a Robson-Ansley, Paula4 aut
700	1	a Alves, Rodrigo Rodrigues4 aut
700	1	a Roje, Zeljka4 aut
700	1	a Rondon, Carmen4 aut
700	1	a Rudzeviciene, Odilija4 aut
700	1	a Ruëff, Franziska4 aut
700	1	a Rukhadze, Maia4 aut
700	1	a Rumi, Gabriele4 aut
700	1	a Sackesen, Cansin4 aut
700	1	a Santos, Alexandra F4 aut
700	1	a Santucci, Annalisa4 aut
700	1	a Scharf, Christian4 aut
700	1	a Schmidt-Weber, Carsten4 aut
700	1	a Schnyder, Benno4 aut
700	1	a Schwarze, Jürgen4 aut
700	1	a Senna, Gianenrico4 aut
700	1	a Sergejeva, Svetlana,d 19724 aut
700	1	a Seys, Sven4 aut
700	1	a Siracusa, Andrea4 aut
700	1	a Skypala, Isabel4 aut
700	1	a Sokolowska, Milena4 aut
700	1	a Spertini, Francois4 aut
700	1	a Spiewak, Radoslaw4 aut
700	1	a Sprikkelman, Aline4 aut
700	1	a Sturm, Gunter4 aut
700	1	a Swoboda, Ines4 aut
700	1	a Terreehorst, Ingrid4 aut
700	1	a Toskala, Elina4 aut
700	1	a Traidl-Hoffmann, Claudia4 aut
700	1	a Venter, Carina4 aut
700	1	a Vlieg-Boerstra, Berber4 aut
700	1	a Whitacker, Paul4 aut
700	1	a Worm, Margitta4 aut
700	1	a Xepapadaki, Paraskevi4 aut
700	1	a Akdis, Cezmi A4 aut
710	2	a Göteborgs universitetb Krefting Research Centre4 org
773	0	t Clinical and translational allergyd : Wileyg 2:1q 2:1x 2045-7022
856	4	u https://gup.ub.gu.se/publication/172635x primaryx freey FULLTEXT
856	4	u https://ctajournal.biomedcentral.com/track/pdf/10.1186/2045-7022-2-21
856	4 8	u https://gup.ub.gu.se/publication/172635
856	4 8	u https://doi.org/10.1186/2045-7022-2-21
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:223121771

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Av författaren/redakt...: Papadopoulos, Ni ...; Agache, Ioana; Bavbek, Sevim; Bilo, Beatrice M; Braido, Fulvio; Cardona, Victori ...; visa fler...; Custovic, Adnan; Demonchy, Jan; Demoly, Pascal; Eigenmann, Phili ...; Gayraud, Jacques; Grattan, Clive; Heffler, Enrico; Hellings, Peter ...; Jutel, Marek; Knol, Edward; Lötvall, Jan, 19 ...; Muraro, Antonell ...; Poulsen, Lars K; Roberts, Graham; Schmid-Grendelme ...; Skevaki, Chrysan ...; Triggiani, Massi ...; Vanree, Ronald; Werfel, Thomas; Flood, Breda; Palkonen, Susann ...; Savli, Roberta; Allegri, Pia; Annesi-Maesano, ...; Annunziato, Fran ...; Antolin-Amerigo, ...; Apfelbacher, Chr ...; Blanca, Miguel; Bogacka, Ewa; Bonadonna, Patri ...; Bonini, Matteo; Boyman, Onur; Brockow, Knut; Burney, Peter; Buters, Jeroen; Butiene, Indre; Calderon, Moises; Cardell, Lars Ol ...; Caubet, Jean-Chr ...; Celenk, Sevcan; Cichocka-Jarosz, ...; Cingi, Cemal; Couto, Mariana; Dejong, Nicolett ...; Del Giacco, Stef ...; Douladiris, Niko ...; Fassio, Filippo; Fauquert, Jean-L ...; Fernandez, Javie ...; Rivas, Montserra ...; Ferrer, Marta; Flohr, Carsten; Gardner, James; Genuneit, Jon; Gevaert, Philipp ...; Groblewska, Anna; Hamelmann, Eckar ...; Hoffmann, Hans J ...; Hoffmann-Sommerg ...; Hovhannisyan, Li ...; Hox, Valérie; Jahnsen, Frode L; Kalayci, Omer; Kalpaklioglu, Ay ...; Kleine-Tebbe, Jö ...; Konstantinou, Ge ...; Kurowski, Marcin; Lau, Susanne; Lauener, Roger; Lauerma, Antti; Logan, Kirsty; Magnan, Antoine; Makowska, Joanna; Makrinioti, Heid ...; Mangina, Paraske ...; Manole, Felicia; Mari, Adriano; Mazon, Angel; Mills, Clare; Mingomataj, Ervi ...; Niggemann, Bodo; Nilsson, Gunnar; Ollert, Markus; O'Mahony, Liam; O'Neil, Serena, ...; Pala, Gianni; Papi, Alberto; Passalacqua, Gia ...; Perkin, Michael; Pfaar, Oliver; Pitsios, Constan ...; Quirce, Santiago; Raap, Ulrike; Raulf-Heimsoth, ...; Rhyner, Claudio; Robson-Ansley, P ...; Alves, Rodrigo R ...; Roje, Zeljka; Rondon, Carmen; Rudzeviciene, Od ...; Ruëff, Franziska; Rukhadze, Maia; Rumi, Gabriele; Sackesen, Cansin; Santos, Alexandr ...; Santucci, Annali ...; Scharf, Christia ...; Schmidt-Weber, C ...; Schnyder, Benno; Schwarze, Jürgen; Senna, Gianenric ...; Sergejeva, Svetl ...; Seys, Sven; Siracusa, Andrea; Skypala, Isabel; Sokolowska, Mile ...; Spertini, Franco ...; Spiewak, Radosla ...; Sprikkelman, Ali ...; Sturm, Gunter; Swoboda, Ines; Terreehorst, Ing ...; Toskala, Elina; Traidl-Hoffmann, ...; Venter, Carina; Vlieg-Boerstra, ...; Whitacker, Paul; Worm, Margitta; Xepapadaki, Para ...; Akdis, Cezmi A; visa färre...

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