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Sökning: (WFRF:(Truong Therese)) > (2020-2024) > Cigarette Smoking a...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00010269naa a2200793 4500
001oai:DiVA.org:umu-199386
003SwePub
008220930s2022 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1993862 URI
0247 a https://doi.org/10.1158/1055-9965.EPI-21-11762 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Dimou, Nikiu Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut
2451 0a Cigarette Smoking and Endometrial Cancer Risk :b observational and Mendelian Randomization Analyses
264 1b American Association for Cancer Research,c 2022
338 a electronic2 rdacarrier
520 a BACKGROUND: Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of smoking in endometrial cancer risk, we conducted complementary observational and Mendelian randomization (MR) analyses.METHODS: The observational analyses included 286,415 participants enrolled in the European Prospective Investigation into Cancer and Nutrition and 179,271 participants in the UK Biobank, and multivariable Cox proportional hazards models were used. In two-sample MR analyses, genetic variants robustly associated with lifetime amount of smoking (n = 126 variants) and ever having smoked regularly (n = 112 variants) were selected and their association with endometrial cancer risk (12,906 cancer/108,979 controls from the Endometrial Cancer Association Consortium) was examined.RESULTS: In the observational analysis, lifetime amount of smoking and ever having smoked regularly were associated with a lower endometrial cancer risk. In the MR analysis accounting for body mass index, a genetic predisposition to a higher lifetime amount of smoking was not associated with endometrial cancer risk (OR per 1-SD increment: 1.15; 95% confidence interval: 0.91-1.44). Genetic predisposition to ever having smoked regularly was not associated with risk of endometrial cancer.CONCLUSIONS: Smoking was inversely associated with endometrial cancer in the observational analyses, although unsupported by the MR. Additional studies are required to better understand the possible confounders and mechanisms underlying the observed associations between smoking and endometrial cancer. IMPACT: The results from this analysis indicate that smoking is unlikely to be causally linked with endometrial cancer risk.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
7001 a Omiyale, Wemimou Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom4 aut
7001 a Biessy, Carineu Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut
7001 a Viallon, Vivianu Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut
7001 a Kaaks, Rudolfu Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany4 aut
7001 a O'Mara, Tracy A.u Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, QLD, Brisbane, Australia4 aut
7001 a Aglago, Elom K.u Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut
7001 a Ardanaz, Evau Navarra Public Health Institute, Pamplona, Spain; IdiSNA, Navarra Institute for Health Research, Pamplona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Spain4 aut
7001 a Bergmann, Manuela M.u German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany4 aut
7001 a Bondonno, Nicola P.u Danish Cancer Society Research Center, Copenhagen, Denmark4 aut
7001 a Braaten, Tonjeu Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway4 aut
7001 a Colorado-Yohar, Sandra M.u CIBER Epidemiología y Salud Pública (CIBERESP), Spain; Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain; Research Group on Demography and Health, National Faculty of Public Health, University of Antioquia, Medellín, Colombia4 aut
7001 a Crous-Bou, Martau Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO) - Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain; Department of Epidemiology, Harvard T.H. Chan School of Public Health. Boston, MA, United States4 aut
7001 a Dahm, Christina C.u Department of Public Health, Aarhus University, Aarhus, Denmark4 aut
7001 a Fortner, Renée Tu Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany4 aut
7001 a Gram, Inger T.u Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway4 aut
7001 a Harlid, Sophia,d 1978-u Umeå universitet,Obstetrik och gynekologi4 aut0 (Swepub:umu)soha0105
7001 a Heath, Alicia K.u Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom4 aut
7001 a Idahl, Annika,d 1965-u Umeå universitet,Obstetrik och gynekologi4 aut0 (Swepub:umu)anid0002
7001 a Kvaskoff, Marinau UVSQ, Inserm CESP U1018, Gustave Roussy, Université Paris-Saclay, Villejuif, France4 aut
7001 a Nøst, Therese H.u Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway4 aut
7001 a Overvad, Kimu Department of Public Health, Aarhus University, Aarhus, Denmark4 aut
7001 a Palli, Domenicou Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy4 aut
7001 a Perez-Cornago, Aurorau Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom4 aut
7001 a Sacerdote, Carlottau Unit of Cancer Epidemiology, Città della Salute e della Scienza University-Hospital, Turin, Italy4 aut
7001 a Sánchez, Maria-Joseu Escuela Andaluza de Salud Pública (EASP), Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain4 aut
7001 a Schulze, Matthias B.u Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; Institute of Nutritional Science, University of Potsdam, Potsdam, Germany4 aut
7001 a Severi, Gianlucau UVSQ, Inserm CESP U1018, Gustave Roussy, Université Paris-Saclay, Villejuif, France; Department of Statistics, Computer Science, Applications "G. Parenti", University of Florence, Florence, Italy4 aut
7001 a Simeon, Vittoriou Dipartimento di Salute Mentale e Fisica e Medicina Preventiva, University of Naples "L. Vanvitelli", Naples, Italy4 aut
7001 a Tagliabue, Giovannau Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori Via Venezian 1, Milan, Italy4 aut
7001 a Tjønneland, Anneu Department of Public Health, University of Copenhagen, Copenhagen, Denmark4 aut
7001 a Truong, Thérèseu UVSQ, Inserm CESP U1018, Gustave Roussy, Université Paris-Saclay, Villejuif, France4 aut
7001 a Tumino, Rosariou Hyblean Association for Epidemiological Research, Ragusa, Italy4 aut
7001 a Johansson, Mattiasu Section of Genetics, International Agency for Research on Cancer, Lyon, France4 aut
7001 a Weiderpass, Elisabeteu Office of the Director, International Agency for Research on Cancer, World Health Organization, Lyon, France4 aut
7001 a Murphy, Neilu Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut
7001 a Gunter, Marc J.u Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut
7001 a Lacey, Benu Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom4 aut
7001 a Allen, Naomi E.u Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom4 aut
7001 a Dossus, Laureu Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France4 aut
7102 a Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, Franceb Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom4 org
7730 t Cancer Epidemiology, Biomarkers and Preventiond : American Association for Cancer Researchg 31:9, s. 1839-1848q 31:9<1839-1848x 1055-9965x 1538-7755
8564 u https://doi.org/10.1158/1055-9965.EPI-21-1176y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1700193/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-199386
8564 8u https://doi.org/10.1158/1055-9965.EPI-21-1176

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