A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.

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Fältnamn	Indikatorer	Metadata
000		15689naa a2201489 4500
001		oai:DiVA.org:liu-135511
003		SwePub
008		170316s2017 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:135262465
009		oai:gup.ub.gu.se/250636
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1355112 URI
024	7	a https://doi.org/10.1080/2000656X.2016.12632022 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1352624652 URI
024	7	a https://gup.ub.gu.se/publication/2506362 URI
040		a (SwePub)liud (SwePub)kid (SwePub)gu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Semb, Gunvoru Division of Dentistry, University of Manchester , Manchester , UK; Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway; Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway.4 aut
245	1 0	a A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
264	1	b Taylor & Francis,c 2017
338		a print2 rdacarrier
500		a Funding agencies: University of Manchester; University Hospital Rikshospitalet; Statped sorost, Oslo; European Commission Biomed II Programme; European Commission Framework V Programme; Swedish Research Council for Health, Working Life and Welfare [2011-1443]
520		a BACKGROUND AND AIMS: Longstanding uncertainty surrounds the selection of surgical protocols for the closure of unilateral cleft lip and palate, and randomised trials have only rarely been performed. This paper is an introduction to three randomised trials of primary surgery for children born with complete unilateral cleft lip and palate (UCLP). It presents the protocol developed for the trials in CONSORT format, and describes the management structure that was developed to achieve the long-term engagement and commitment required to complete the project.METHOD: Ten established national or regional cleft centres participated. Lip and soft palate closure at 3-4 months, and hard palate closure at 12 months served as a common method in each trial. Trial 1 compared this with hard palate closure at 36 months. Trial 2 compared it with lip closure at 3-4 months and hard and soft palate closure at 12 months. Trial 3 compared it with lip and hard palate closure at 3-4 months and soft palate closure at 12 months. The primary outcomes were speech and dentofacial development, with a series of perioperative and longer-term secondary outcomes.RESULTS: Recruitment of 448 infants took place over a 9-year period, with 99.8% subsequent retention at 5 years.CONCLUSION: The series of reports that follow this introductory paper include comparisons at age 5 of surgical outcomes, speech outcomes, measures of dentofacial development and appearance, and parental satisfaction. The outcomes recorded and the numbers analysed for each outcome and time point are described in the series.TRIAL REGISTRATION: ISRCTN29932826.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oto-rhino-laryngologi0 (SwePub)302182 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Otorhinolaryngology0 (SwePub)302182 hsv//eng
653		a Scandcleft Project
653		a multicentre study
653		a randomised controlled trials
653		a surgery for unilateral complete cleft lip and palate
700	1	a Enemark, Hansu Cleft Palate Center , Aarhus , Denmark4 aut
700	1	a Friede, Hans,d 1938u Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology4 aut0 (Swepub:gu)xfrieh
700	1	a Paulin, Gunnaru Region Östergötland, Käkkliniken US4 aut0 (Swepub:liu)gunpa61
700	1	a Lilja, Jan,d 1942u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery4 aut0 (Swepub:gu)xliljj
700	1	a Rautio, Jormau Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Andersen, Mikaelu Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Åbyholm, Franku Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway4 aut
700	1	a Lohmander, Anetteu Karolinska Institutet,Division of Speech and Language Pathology , Karolinska Institute, and Karolinska University Hospital , Stockholm , Sweden4 aut
700	1	a Shaw, Williamu Division of Dentistry, University of Manchester , Manchester , UK4 aut
700	1	a Mølsted, Kirstenu Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Heliövaara, Arjau Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Bolund, Stigu Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Hukki, Jyriu Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Vindenes, Hallvardu Centre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway4 aut
700	1	a Davenport, Peteru Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Arctander, Kjartanu Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway4 aut
700	1	a Larson, Olau Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden4 aut
700	1	a Berggren, Andersu Region Östergötland, Hand- och plastikkirurgiska kliniken US4 aut0 (Swepub:liu)andbe26
700	1	a Whitby, Davidu Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Leonard, Alanu The Royal Hospital for Sick Children , Belfast , N. Ireland4 aut
700	1	a Neovius, Eriku Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden4 aut
700	1	a Elander, Anna,d 1955u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery4 aut0 (Swepub:gu)xelaan
700	1	a Willadsen, Elisabethu Department of Nordic Studies and Linguistics , University of Copenhagen , Denmark4 aut
700	1	a Bannister, R. Patriciau Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Bradbury, Eileenu Private Practitioner , Manchester , UK4 aut
700	1	a Henningsson, Gunillau Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden4 aut
700	1	a Persson, Christina,d 1959u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för hälsa och rehabilitering,Institute of Neuroscience and Physiology, Department of Health and Rehabilitation4 aut0 (Swepub:gu)xperch
700	1	a Eyres, Philipu Division of Dentistry, University of Manchester , Manchester , UK4 aut
700	1	a Emborg, Beritu Cleft Palate Center , Aarhus , Denmark4 aut
700	1	a Kisling-Møller, Miau Division of Dentistry, University of Manchester , Manchester , UK4 aut
700	1	a Küseler, Anneliseu Division of Dentistry, University of Manchester , Manchester , UK4 aut
700	1	a Granhof Black, Birtheu Division of Dentistry, University of Manchester , Manchester , UK4 aut
700	1	a Schöps, Antjeu Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Bau, Anjau Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Boers, Mariau Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Søgaard Andersen, Heleneu Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Jeppesen, Karinu Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Marxen, Dorteu Copenhagen Cleft Palate Center, University Hospital of Copenhagen , Denmark4 aut
700	1	a Paaso, Marjukkau Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Hölttä, Elinau Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Alaluusua, Suviu Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Turunen, Leenau Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Humerinta, Kirstiu Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Elfving-Little, Ullau Cleft Palate and Craniofacial Center, Helsinki University Central Hospital , Helsinki , Finland4 aut
700	1	a Tørdal, Inger Beateu Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway4 aut
700	1	a Kjøll, Lillianu Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway4 aut
700	1	a Aukner, Ragnhildu Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway4 aut
700	1	a Hide, Øydisu Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway4 aut
700	1	a Feragen, Kristin Billaudu Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway4 aut
700	1	a Rønning, Elisabethu Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway4 aut
700	1	a Skaare, Pålu Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway4 aut
700	1	a Brinck, Eliu Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway4 aut
700	1	a Semmingsen, Ann-Magrittu Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway4 aut
700	1	a Lindberg, Ninau Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway4 aut
700	1	a Bowden, Melanieu Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Davies, Julieu Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Mooney, Jeanetteu Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Bellardie, Haydnu Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Schofield, Ninau Greater Manchester Cleft Lip and Palate Unit , Royal Manchester Childrens' Hospital , Manchester , UK4 aut
700	1	a Nyberg, Jillu Karolinska Institutet,Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden4 aut
700	1	a Lundberg, Mariau Stockholm Craniofacial Team , Karolinska University Hospital , Stockholm , Sweden4 aut
700	1	a Linder-Aronson Karsten, Agnetau Stockholm Craniofacial Team, Department of Dental Medicine , Karolinska Institute , Stockholm , Sweden4 aut
700	1	a Larson, Margaretau Eastman Institute, Stockholms Läns Landsting , Stockholm , Sweden4 aut
700	1	a Holmefjord, Andersu Statped vest , Bergen , Norway4 aut
700	1	a Reisæter, Sigvoru Statped vest , Bergen , Norway4 aut
700	1	a Pedersen, Nina-Helenu Statped vest , Bergen , Norway4 aut
700	1	a Rasmussen, Thereseu Statped vest , Bergen , Norway4 aut
700	1	a Tindlund, Rolfu Dental School, University of Bergen , Bergen , Norway4 aut
700	1	a Sæle, Paulu Oral Health Center of Expertise/Western Norway , Bergen , Norway4 aut
700	1	a Blomhoff, Reidunnu Centre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway4 aut
700	1	a Jacobsen, Gryu Centre for Cleft Lip and Palate, Bergen University Hospital Haukeland , Bergen , Norway4 aut
700	1	a Havstam, Christinau Division for Speech and Language Pathology , Sahlgrenska University Hospital , Gothenburg , Sweden4 aut
700	1	a Rizell, Sara,d 1963u Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology4 aut0 (Swepub:gu)xrizsa
700	1	a Enochson, Larsu Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för klinisk kemi och transfusionsmedicin,Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine4 aut0 (Swepub:gu)xenola
700	1	a Hagberg, Catharina,d 1949u Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology4 aut0 (Swepub:gu)xhagbc
700	1	a Najar Chalien, Midiau Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology4 aut
700	1	a Paganini, Anna,d 1979u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery4 aut0 (Swepub:gu)xpagan
700	1	a Lundeborg, Inger,d 1956-u Linköpings universitet,Avdelningen för Logopedi, Audiologi och Otorhinolaryngologi,Medicinska fakulteten4 aut0 (Swepub:liu)inglu20
700	1	a Marcusson, Agneta,d 1956-u Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Käkkliniken US4 aut0 (Swepub:liu)agnma12
700	1	a Mjönes, Anna-Brittau Region Östergötland, Öron- näsa- och halskliniken US4 aut0 (Swepub:liu)annmj11
700	1	a Gustavsson, Annicau Region Östergötland, Käkkliniken US4 aut
700	1	a Hayden, Christineu The Royal Hospital for Sick Children , Belfast , N. Ireland4 aut
700	1	a McAleer, Eilishu The Royal Hospital for Sick Children , Belfast , N. Ireland4 aut
700	1	a Slevan, Emmau The Royal Hospital for Sick Children , Belfast , N. Ireland4 aut
700	1	a Gregg, Terryu The Royal Hospital for Sick Children , Belfast , N. Ireland4 aut
700	1	a Worthington, Helenu Division of Dentistry, University of Manchester , Manchester , UK4 aut
700	1	a Hide, O4 aut
700	1	a Saele, P4 aut
710	2	a Division of Dentistry, University of Manchester , Manchester , UK; Department of Plastic and Reconstructive Surgery , Oslo University Hospital Rikshospitalet , Oslo , Norway; Department of Speech and Language Disorders , Statped sørøst , Oslo , Norway.b Cleft Palate Center , Aarhus , Denmark4 org
773	0	t Journal of Plastic Surgery and Hand Surgeryd : Taylor & Francisg 51:1, s. 2-13q 51:1<2-13x 2000-656Xx 2000-6764
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-135511
856	4 8	u https://doi.org/10.1080/2000656X.2016.1263202
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:135262465
856	4 8	u https://gup.ub.gu.se/publication/250636

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Av författaren/redakt...: Semb, Gunvor; Enemark, Hans; Friede, Hans, 19 ...; Paulin, Gunnar; Lilja, Jan, 1942; Rautio, Jorma; visa fler...; Andersen, Mikael; Åbyholm, Frank; Lohmander, Anett ...; Shaw, William; Mølsted, Kirsten; Heliövaara, Arja; Bolund, Stig; Hukki, Jyri; Vindenes, Hallva ...; Davenport, Peter; Arctander, Kjart ...; Larson, Ola; Berggren, Anders; Whitby, David; Leonard, Alan; Neovius, Erik; Elander, Anna, 1 ...; Willadsen, Elisa ...; Bannister, R. Pa ...; Bradbury, Eileen; Henningsson, Gun ...; Persson, Christi ...; Eyres, Philip; Emborg, Berit; Kisling-Møller, ...; Küseler, Annelis ...; Granhof Black, B ...; Schöps, Antje; Bau, Anja; Boers, Maria; Søgaard Andersen ...; Jeppesen, Karin; Marxen, Dorte; Paaso, Marjukka; Hölttä, Elina; Alaluusua, Suvi; Turunen, Leena; Humerinta, Kirst ...; Elfving-Little, ...; Tørdal, Inger Be ...; Kjøll, Lillian; Aukner, Ragnhild; Hide, Øydis; Feragen, Kristin ...; Rønning, Elisabe ...; Skaare, Pål; Brinck, Eli; Semmingsen, Ann- ...; Lindberg, Nina; Bowden, Melanie; Davies, Julie; Mooney, Jeanette; Bellardie, Haydn; Schofield, Nina; Nyberg, Jill; Lundberg, Maria; Linder-Aronson K ...; Larson, Margaret ...; Holmefjord, Ande ...; Reisæter, Sigvor; Pedersen, Nina-H ...; Rasmussen, There ...; Tindlund, Rolf; Sæle, Paul; Blomhoff, Reidun ...; Jacobsen, Gry; Havstam, Christi ...; Rizell, Sara, 19 ...; Enochson, Lars; Hagberg, Cathari ...; Najar Chalien, M ...; Paganini, Anna, ...; Lundeborg, Inger ...; Marcusson, Agnet ...; Mjönes, Anna-Bri ...; Gustavsson, Anni ...; Hayden, Christin ...; McAleer, Eilish; Slevan, Emma; Gregg, Terry; Worthington, Hel ...; Hide, O; Saele, P; visa färre...

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