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First experiences o...
First experiences of a low-dose protocol for CT-guided musculoskeletal biopsies combining different radiation dose reduction techniques
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- Alagic, Zlatan (author)
- Karolinska Institutet
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- Alagic, Haris (author)
- Karolinska Inst, Inst Mol Med & Surg MMK, Diagnost Radiol, Stockholm, Sweden.
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- Bujila, Robert (author)
- KTH,Medicinsk bildfysik
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- Srivastava, Subhash (author)
- Karolinska Univ Hosp, Funct Unit Musculoskeletal Radiol Funct Imaging &, S-17176 Stockholm, Sweden.
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- Jasim, Saif (author)
- Karolinska Univ Hosp, Funct Unit Musculoskeletal Radiol Funct Imaging &, S-17176 Stockholm, Sweden.
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- Lindqvist, Maria (author)
- Karolinska Univ Hosp, Funct Unit Musculoskeletal Radiol Funct Imaging &, S-17176 Stockholm, Sweden.
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- Wick, Marius C. (author)
- Karolinska Univ Hosp, Funct Unit Musculoskeletal Radiol Funct Imaging &, S-17176 Stockholm, Sweden.;Karolinska Inst, Inst Mol Med & Surg MMK, Diagnost Radiol, Stockholm, Sweden.
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Karolinska Institutet Karolinska Inst, Inst Mol Med & Surg MMK, Diagnost Radiol, Stockholm, Sweden (creator_code:org_t)
- 2019-05-15
- 2020
- English.
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In: Acta Radiologica. - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 61:1, s. 28-36
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Background The use of computed tomography (CT) for image guidance during biopsies is a powerful approach. The method is, however, often associated with a significant level of radiation exposure to the patient and operator. Purpose To investigate if a low-dose protocol for CT-guided musculoskeletal (MSK) biopsies, including a combination of different radiation dose (RD) techniques, is feasible in a clinical setting. Material and Methods Fifty-seven patients underwent CT-guided fine-needle aspiration cytology (FNAC) utilizing the low-dose protocol (group A). A similar number of patients underwent CT-guided FNAC using the reference protocol (group B). Between-group comparisons comprised radiation dose, success rate, image quality parameters, and workflow. Results In group A, the mean total dose-length product (DLP) was 41.2 +/- 2.9 mGy*cm, which was statistically significantly lower than of group B (257.4 +/- 22.0 mGy*cm), corresponding to a mean dose reduction of 84% (P<0.001). The mean CTDIvol for the control scans were 1.88 +/- 0.09 mGy and 13.16 +/- 0.40 mGy for groups A and B, respectively (P < 0.001). The success rate in group A was 91.2% and 87.9% in group B (P = 0.56). No negative effect on image-quality parameters, time of FNAC, and number of control scans were found. Conclusion We successfully developed a low-dose protocol for CT-guided MSK biopsies that maintains diagnostic accuracy and image quality at a fraction of the RD compared to the reference biopsy protocol at our clinic.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- Image-guided biopsy
- interventional radiology
- multidetector computed tomography
- musculoskeletal system
- radiation dosage
Publication and Content Type
- ref (subject category)
- art (subject category)
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