An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction.

Adner, Mikael (author): Lund University,Lunds universitet,Klinisk och experimentell allergiforskning,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Clinical and Experimental Allergy Research,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups,Malmö University Hospital, Sweden

Rose, Andrew C (author): Johnson and Johnson Pharmaceutical Research and Development, La Jolla, California, USA

Zhang, Yaping (author): Lund University,Lunds universitet,Klinisk och experimentell allergiforskning,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Clinical and Experimental Allergy Research,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups,Malmö University Hospital, Sweden

Swärd, Karl (author): Lund University,Lunds universitet,Cellulär biomekanik,Forskargrupper vid Lunds universitet,Cellular Biomechanics,Lund University Research Groups,Lund University, Sweden

Uddman, Rolf (author): Lund University,Lunds universitet,Klinisk och experimentell allergiforskning,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Clinical and Experimental Allergy Research,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups,Malmö University Hospital, Sweden

Shankley, Nigel P (author): Johnson and Johnson Pharmaceutical Research and Development, La Jolla, California, USA

Cardell, Lars-Olaf (author): Lund University,Lunds universitet,Klinisk och experimentell allergiforskning,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Clinical and Experimental Allergy Research,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups,Malmö University Hospital, Sweden

(creator_code:org_t)

2009-02-02
2002
English.
In: British Journal of Pharmacology. - : Wiley. - 1476-5381 .- 0007-1188. ; 137:7, s. 971-982

Related links:: http://www.ncbi.nlm....; show more...; http://dx.doi.org/10...; https://europepmc.or...; https://lup.lub.lu.s...; https://doi.org/10.1...; https://urn.kb.se/re...; show less...

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)

Dose-Response Relationship
Carbachol: pharmacology
Gene Expression Profiling
Inflammation Mediators: pharmacology
Drug
Muscle
Animal
Muscle Contraction: drug effects
Muscarinic Antagonists: pharmacology
Inbred BALB C
Smooth: drug effects
Receptors
Potassium Chloride: pharmacology
Oligonucleotide Array Sequence Analysis
Organ Culture
Smooth: physiology
Tumor Necrosis Factor: pharmacology
Trachea: physiology
Trachea: metabolism
Non-U.S. Gov't
Trachea: drug effects
Time Factors
Serotonin: drug effects
Support
Serotonin Antagonists: pharmacology
Serotonin Agonists: pharmacology
Serotonin Agents: pharmacology
Serotonin: physiology
Serotonin: pharmacology
Male
Isoproterenol: pharmacology
Mice
Atropine: pharmacology
5-HT2A receptors; airway hyperresponsiveness; airway remodelling; asthma; contractile phenotype; DNA microarray; organ culture; tracheal segments; tumour necrosis factor-alpha

By the author/editor: Adner, Mikael; Rose, Andrew C; Zhang, Yaping; Swärd, Karl; Benson, Mikael; Uddman, Rolf; show more...; Shankley, Nigel ...; Cardell, Lars-Ol ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Pharmacology and ...

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