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A 5-year prospectiv...
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Aghajanzadeh, SusanGothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences
(författare)
A 5-year prospective study of health-related quality of life in irradiated head and neck cancer patients: three trends of HRQL over time
- Artikel/kapitelEngelska2023
Förlag, utgivningsår, omfång ...
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2023-01-11
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Springer Science and Business Media LLC,2023
Nummerbeteckningar
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LIBRIS-ID:oai:gup.ub.gu.se/323978
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https://gup.ub.gu.se/publication/323978URI
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https://doi.org/10.1007/s00405-022-07789-7DOI
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Purpose Head and neck cancer (HNC) is one of the fastest increasing cancer-types, where both disease and oncologic treatment have severe impact on health-related quality of life (HRQL). This study aimed to report HRQL prospectively up to 5-years following radiotherapy-treatment in HNC and to, if possible, identify trends in HRQL over time. Methods This prospective study followed 211 patients receiving curatively intended radiotherapy pre-diagnosis, 3-, 6-, 12- and 60-months post-radiotherapy completion. HRQL was measured using EORTC QLQ-C30 and EORTC QLQ-HN35. Results A deterioration three months post-radiotherapy was reported in 14/15 domains of EORTC QLQ-C30. Eight out of 12 domains had recovered to baseline-values at 12 months post-radiotherapy and remained unchanged up to study endpoint. Corresponding figures for EORTC QLQ-HN35 were deteriorations in 15/16 domains at three months post-radiotherapy, with recovery of 5 domain at 12-months, whereas the other 11 domains remained significantly worse at 5-years post-RT compared to baseline. Conclusion Following the deterioration in HRQL seen immediately following radiotherapy, the continued course of HRQL can be divided into three trends: short-term deterioration, long-term deterioration and long-term improvements. The combination of disease- and diagnosis-specific questionnaires is crucial when assessing HRQL in the HNC population.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Tuomi, Lisa,1985Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institutionen för kliniska vetenskaper,Institute of Neuroscience and Physiology,Institute of Clinical Sciences(Swepub:gu)xtuoli
(författare)
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Karlsson, Therese,1987Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xkther
(författare)
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Göteborgs universitetInstitutionen för kliniska vetenskaper
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:European Archives of Oto-Rhino-Laryngology: Springer Science and Business Media LLC280:5, s. 2617-220937-44771434-4726
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