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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03451naa a2200361 4500 | |
| 001 | oai:gup.ub.gu.se/323978 | |
| 003 | SwePub | |
| 008 | 240528s2023 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/3239782 URI |
| 024 | 7 | a https://doi.org/10.1007/s00405-022-07789-72 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Aghajanzadeh, Susanu Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xaghsu |
| 245 | 1 0 | a A 5-year prospective study of health-related quality of life in irradiated head and neck cancer patients: three trends of HRQL over time |
| 264 | c 2023-01-11 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2023 |
| 520 | a Purpose Head and neck cancer (HNC) is one of the fastest increasing cancer-types, where both disease and oncologic treatment have severe impact on health-related quality of life (HRQL). This study aimed to report HRQL prospectively up to 5-years following radiotherapy-treatment in HNC and to, if possible, identify trends in HRQL over time. Methods This prospective study followed 211 patients receiving curatively intended radiotherapy pre-diagnosis, 3-, 6-, 12- and 60-months post-radiotherapy completion. HRQL was measured using EORTC QLQ-C30 and EORTC QLQ-HN35. Results A deterioration three months post-radiotherapy was reported in 14/15 domains of EORTC QLQ-C30. Eight out of 12 domains had recovered to baseline-values at 12 months post-radiotherapy and remained unchanged up to study endpoint. Corresponding figures for EORTC QLQ-HN35 were deteriorations in 15/16 domains at three months post-radiotherapy, with recovery of 5 domain at 12-months, whereas the other 11 domains remained significantly worse at 5-years post-RT compared to baseline. Conclusion Following the deterioration in HRQL seen immediately following radiotherapy, the continued course of HRQL can be divided into three trends: short-term deterioration, long-term deterioration and long-term improvements. The combination of disease- and diagnosis-specific questionnaires is crucial when assessing HRQL in the HNC population. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oto-rhino-laryngologi0 (SwePub)302182 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Otorhinolaryngology0 (SwePub)302182 hsv//eng |
| 653 | a Radiotherapy | |
| 653 | a Head and neck neoplasm | |
| 653 | a Quality of life | |
| 653 | a european-organization | |
| 653 | a Otorhinolaryngology | |
| 700 | 1 | a Tuomi, Lisa,d 1985u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institutionen för kliniska vetenskaper,Institute of Neuroscience and Physiology,Institute of Clinical Sciences4 aut0 (Swepub:gu)xtuoli |
| 700 | 1 | a Karlsson, Therese,d 1987u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences4 aut0 (Swepub:gu)xkther |
| 710 | 2 | a Göteborgs universitetb Institutionen för kliniska vetenskaper4 org |
| 773 | 0 | t European Archives of Oto-Rhino-Laryngologyd : Springer Science and Business Media LLCg 280:5, s. 2617-22q 280:5<2617-22x 0937-4477x 1434-4726 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/323978 |
| 856 | 4 8 | u https://doi.org/10.1007/s00405-022-07789-7 |
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