Sökning: LAR1:gu > Skoog Ingmar 1954 > Östling Svante 1953 > Tidskriftsartikel > Hällström Tore 1935 > (2013) > Common psychosocial...
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000 | 05898naa a2200445 4500 | |
001 | oai:gup.ub.gu.se/184689 | |
003 | SwePub | |
008 | 240910s2013 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:128238505 | |
024 | 7 | a https://gup.ub.gu.se/publication/1846892 URI |
024 | 7 | a https://doi.org/10.1136/bmjopen-2013-0031422 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1282385052 URI |
040 | a (SwePub)gud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Johansson, Lena,d 1972u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xjlena |
245 | 1 0 | a Common psychosocial stressors in middle-aged women related to longstanding distress and increased risk of Alzheimer’s disease: a 38 year longitudinal population study |
264 | c 2013-09-30 | |
264 | 1 | b BMJ,c 2013 |
338 | a electronic2 rdacarrier | |
520 | a OBJECTIVE: To study the relation among psychosocial stressors, long-standing distress and incidence of dementia, in a sample of women followed from midlife to late life. DESIGN: Prospective longitudinal population study. SETTING: The analyses originate from the prospective population study of women in Gothenburg, Sweden, a representative sample of women examined in 1968 (participation rate 90%) and re-examined in 1974, 1980, 1992, 2000 and 2005. PARTICIPANTS: 800 women born in 1914, 1918, 1922 and 1930 who were systematically selected for a psychiatric examination at baseline, in 1968. PRIMARY AND SECONDARY OUTCOME MEASURES: 18 psychosocial stressors (eg, divorce, widowhood, work problems and illness in relative) were obtained at baseline. Symptoms of distress were measured according to a standardised question at each study wave. Dementia was diagnosed according to Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R) criteria based on information from neuropsychiatric examinations, informant interviews, hospital records, and registry data, and measured through the whole study period. RESULTS: During the 37 years of follow-up, 153 women developed dementia (104 of those had Alzheimer's disease (AD)). Number of psychosocial stressors in 1968 was associated (HR, 95% CI) with higher incidence of dementia (1.15, 1.04 to 1.27) and AD (1.20, 1.07 to 1.35) between 1968 and 2005, in multivariate Cox regressions. Number of psychosocial stressors in 1968 was also associated (OR, 95% CI) with distress in 1968 (1.48, 1.32 to 1.67), 1974 (1.31, 1.17 to 1.46), 1980 (1.27, 1.11 to 1.45), 2000 (1.39, 1.14 to 1.70) and 2005 (1.35, 1.02 to 1.79), in multivariate logistic regressions. Number of psychosocial stressors (HR 1.17, 95% CI 1.03 to 1.33) and long-standing distress (1968-1974-1980) (HR 1.58, 95% CI 1.03 to 2.45) were independently associated with AD. CONCLUSIONS: Our study shows that common psychosocial stressors may have severe and long-standing physiological and psychological consequences. However, more studies are needed to confirm these results and investigate whether more interventions such as stress management and behavioural therapy should be initiated in individuals who have experienced psychosocial stressors. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Annan medicin och hälsovetenskap0 (SwePub)3052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Other Medical and Health Sciences0 (SwePub)3052 hsv//eng |
653 | a EPIDEMIOLOGY | |
700 | 1 | a Guo, Xinxin,d 1972u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xguoxi |
700 | 1 | a Hällström, Tore,d 1935u Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xhaltn |
700 | 1 | a Norton, Maria C4 aut |
700 | 1 | a Waern, Margda,d 1955u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xwaema |
700 | 1 | a Östling, Svante,d 1953u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xostsv |
700 | 1 | a Bengtsson, Calle,d 1934u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xbengc |
700 | 1 | a Skoog, Ingmar,d 1954u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry4 aut0 (Swepub:gu)xskooi |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi4 org |
773 | 0 | t BMJ Opend : BMJg 3:9q 3:9x 2044-6055 |
856 | 4 | u https://gup.ub.gu.se/publication/184689x primaryx freey FULLTEXT |
856 | 4 | u https://bmjopen.bmj.com/content/3/9/e003142.full.pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/184689 |
856 | 4 8 | u https://doi.org/10.1136/bmjopen-2013-003142 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:128238505 |
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