WFRF:(Akhtar Sultan)
Search: WFRF:(Akhtar Sultan) > (2010-2014) > Real-Space Transmis...
- 1 of 14
- Previous record
- Next record
- To hitlist
Real-Space Transmission Electron Microscopy Investigations of Attachment of Functionalized Magnetic Nanoparticles to DNA-Coils Acting as a Biosensor
-
- Akhtar, Sultan (author)
- Uppsala universitet,Experimentell fysik,Electron Microscopy and Nanoengineering
-
- Strömberg, Mattias (author)
- Uppsala universitet,Nanoteknologi och funktionella material
-
- Zardán Gómez de la Torre, Teresa (author)
- Uppsala universitet,Nanoteknologi och funktionella material
- show more...
- show less...
- (creator_code:org_t)
- 2010-09-27
- 2010
- English.
- In: Journal of Physical Chemistry B. - : American Chemical Society (ACS). - 1520-6106 .- 1520-5207. ; 114:41, s. 13255-13262
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- The present work provides the first real-space analysis of nanobead-DNA coil interactions. Immobilization of oligonucleotide-functionalized magnetic nanobeads in rolling circle amplified DNA-coils was studied by complex magnetization measurements and transmission electron microscopy (TEM), and a statistical analysis of the number of beads hybridized to the DNA-coils was performed. The average number of beads per DNAcoil using the results from both methods was found to be around 6 and slightly above 2 for samples with 40 and 130 nm beads, respectively. The TEM analysis supported an earlier hypothesis that 40 nm beads are preferably immobilized in the interior of DNA-coils whereas 130 nm beads, to a larger extent, are immobilized closer to the exterior of the coils. The methodology demonstrated in the present work should open up new possibilities for characterization of interactions of a large variety of functionalized nanoparticles with macromolecules, useful for gaining more fundamental understanding of such interactions as well as for optimizing a number of biosensor applications.
Keyword
- TECHNOLOGY
- TEKNIKVETENSKAP
- Teknisk fysik med inriktning mot nanoteknologi och funktionella material
- Engineering Science with specialization in Nanotechnology and Functional Materials
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Journal of Physical Chemistry B (Search for host publication in LIBRIS)
To the university's database
- 1 of 14
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Akhtar, Sultan
- Strömberg, Matti ...
- Zardán Gómez de ...
- Russell, Camilla
- Gunnarsson, Klas
- Nilsson, Mats
- show more...
- Svedlindh, Peter
- Strömme, Maria
- Leifer, Klaus
- show less...
- Articles in the publication
- Journal of Physi ...
- By the university
- Uppsala University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
