SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Akpan Edifofon)
 

Sökning: WFRF:(Akpan Edifofon) > (2022) > Cost-effectiveness ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006231naa a2200517 4500
001oai:DiVA.org:uu-495801
003SwePub
008230207s2022 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4958012 URI
0247 a https://doi.org/10.1093/ajcn/nqac2252 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Akpan, Edifofonu Univ Melbourne, Ctr Hlth Policy, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia.4 aut
2451 0a Cost-effectiveness of universal iron supplementation and iron-containing micronutrient powders for anemia among young children in rural Bangladesh :b analysis of a randomized, placebo-controlled trial
264 1b OXFORD UNIV PRESS,c 2022
338 a print2 rdacarrier
520 a Background: Universal provision of iron supplements or iron-containing multiple micronutrient powders (MNPs) is widely used to prevent anemia in young children in low- and middle-income countries. The BRISC (Benefits and Risks of Iron Interventions in Children) trial compared iron supplements and MNPs with placebo in children <2 y old in rural Bangladesh. Objectives: We aimed to assess the cost-effectiveness of iron supplements or iron-containing MNPs among young children in rural Bangladesh. Methods: We did a cost-effectiveness analysis of MNPs and iron supplements using the BRISC trial outcomes and resource use data, and programmatic data from the literature. Health care costs were assessed from a health system perspective. We calculated incremental cost-effectiveness ratios (ICERs) in terms of US$ per disability-adjusted life-year (DALY) averted. To explore uncertainty, we constructed cost-effectiveness acceptability curves using bootstrapped data over a range of cost-effectiveness thresholds. One- and 2-way sensitivity analyses tested the impact of varying key parameter values on our results. Results: Provision of MNPs was estimated to avert 0.0031 (95% CI: 0.0022, 0.0041) DALYs/child, whereas iron supplements averted 0.0039 (95% CI: 0.0030, 0.0048) DALYs/child, over 1 y compared with no intervention. Incremental mean costs were $0.75 (95% CI: 0.73, 0.77) for MNPs compared with no intervention and $0.64 ($0.62, $0.67) for iron supplements compared with no intervention. Iron supplementation dominated MNPs because it was cheaper and averted more DALYs. Iron supplementation had an ICER of $1645 ($1333, $2153) per DALY averted compared with no intervention, and had a 0% probability of being the optimal strategy at cost-effectiveness thresholds of $200 (reflecting health opportunity costs in Bangladesh) and $985 [half of gross domestic product (GDP) per capita] per DALY averted. Scenario and sensitivity analyses supported the base case findings. Conclusions: These findings do not support universal iron supplementation or micronutrient powders as a cost-effective intervention for young children in rural Bangladesh.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
653 a iron supplements
653 a micronutrient powders
653 a cost-effectiveness
653 a anemia
653 a trial
653 a children
653 a low- and middle-income country
7001 a Hossain, Sheikh Jamalu Uppsala universitet,Internationell barnhälsa och nutrition,Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh.;Uppsala Univ, Dept Womens & Childrens Hlth, Uppsala, Sweden.4 aut0 (Swepub:uu)sheho716
7001 a Devine, Angelau Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia.;Charles Darwin Univ, Menzies Sch Hlth Res, Div Global & Trop Hlth, Darwin, NT, Australia.4 aut
7001 a Braat, Sabineu Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia.;Walter & Eliza Hall Inst Med Res, Populat Hlth & Immun Div, Parkville, Vic, Australia.;Univ Melbourne, Dept Med Peter Doherty Inst, Parkville, Vic, Australia.4 aut
7001 a Hasan, Mohammed, Iu Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh.4 aut
7001 a Tipu, S. M. Mulk Uddinu Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh.4 aut
7001 a Bhuiyan, Mohammad Saiful Alamu Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh.4 aut
7001 a Hamadani, Jena D.u Bangladesh Icddr B, Maternal & Child Hlth Div, Int Ctr Diarrhoeal Dis Res, Dhaka, Bangladesh.4 aut
7001 a Biggs, Beverley-Annu Univ Melbourne, Dept Med Peter Doherty Inst, Parkville, Vic, Australia.4 aut
7001 a Pasricha, Sant-Raynu Walter & Eliza Hall Inst Med Res, Populat Hlth & Immun Div, Parkville, Vic, Australia.;Royal Melbourne Hosp, Diagnost Hematol, Parkville, Vic, Australia.;Peter MacCallum Canc Ctr, Clin Hematol, Parkville, Vic, Australia.;Royal Melbourne Hosp, Parkville, Vic, Australia.;Univ Melbourne, Dept Med Biol, Parkville, Vic, Australia.4 aut
7001 a Carvalho, Natalieu Univ Melbourne, Ctr Hlth Policy, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia.4 aut
7102 a Univ Melbourne, Ctr Hlth Policy, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia.b Internationell barnhälsa och nutrition4 org
7730 t American Journal of Clinical Nutritiond : OXFORD UNIV PRESSg 116:5, s. 1303-1313q 116:5<1303-1313x 0002-9165x 1938-3207
8564 u https://doi.org/10.1093/ajcn/nqac225y Fulltext
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-495801
8564 8u https://doi.org/10.1093/ajcn/nqac225

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy