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WFRF:(Algaba Ferran)
 

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00007077naa a2200721 4500
001oai:lup.lub.lu.se:3e4879e9-c0b1-4e5f-88cf-8e548957dfd9
003SwePub
008230810s2023 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/3e4879e9-c0b1-4e5f-88cf-8e548957dfd92 URI
0247 a https://doi.org/10.1016/j.euros.2023.03.0192 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Beijert, Irene J.u Academic Medical Center of University of Amsterdam (AMC),Antoni Van Leeuwenhoek Hospital4 aut
2451 0a International Opinions on Grading of Urothelial Carcinoma : A Survey Among European Association of Urology and International Society of Urological Pathology Members
264 1c 2023
300 a 12 s.
520 a Background: Grade of non–muscle-invasive bladder cancer (NMIBC) is an important prognostic factor for progression. Currently, two World Health Organization (WHO) classification systems (WHO1973, categories: grade 1–3, and WHO2004 categories: papillary urothelial neoplasm of low malignant potential [PUNLMP], low-grade [LG], high-grade [HG] carcinoma) are used. Objective: To ask the European Association of Urology (EAU) and International Society of Urological Pathology (ISUP) members regarding their current practice and preferences of grading systems. Design, setting, and participants: A web-based, anonymous questionnaire with ten questions on grading of NMIBC was created. The members of EAU and ISUP were invited to complete an online survey by the end of 2021. Thirteen experts had previously answered the same questions. Outcome measurements and statistical analysis: The submitted answers from 214 ISUP members, 191 EAU members, and 13 experts were analyzed. Results and limitations: Currently, 53% use only the WHO2004 system and 40% use both systems. According to most respondents, PUNLMP is a rare diagnosis with management similar to Ta-LG carcinoma. The majority (72%) would consider reverting back to WHO1973 if grading criteria were more detailed. Separate reporting of WHO1973-G3 within WHO2004-HG would influence clinical decisions for Ta and/or T1 tumors according the majority (55%). Most respondents preferred a two-tier (41%) or a three-tier (41%) grading system. The current WHO2004 grading system is supported by a minority (20%), whereas nearly half (48%) supported a hybrid three- or four-tier grading system composed of both WHO1973 and WHO2004. The survey results of the experts were comparable with ISUP and EAU respondents. Conclusions: Both the WHO1973 and the WHO2004 grading system are still widely used. Even though opinions on the future of bladder cancer grading were strongly divided, there was limited support for WHO1973 and WHO2004 in their current formats, while the hybrid (three-tier) grading system with LG, HG-G2, and HG-G3 as categories could be considered the most promising alternative. Patient summary: Grading of non–muscle-invasive bladder cancer (NMIBC) is a matter of ongoing debate and lacks international consensus. We surveyed urologists and pathologists of European Association of Urology and International Society of Urological Pathology on their preferences regarding NMIBC grading to generate a multidisciplinary dialogue. Both the “old” World Health Organization (WHO) 1973 and the “new” WHO2004 grading schemes are still used widely. However, continuation of both the WHO1973 and the WHO2004 system showed limited support, while a hybrid grading system composed of both the WHO1973 and the WHO2004 classification system may be considered a promising alternative.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
653 a Bladder
653 a Cancer
653 a European Association of Urology
653 a Grading
653 a International Society of Urological Pathology
653 a Survey
653 a WHO1973
653 a WHO2004
7001 a Cheng, Liangu Brown University4 aut
7001 a Liedberg, Fredriku Lund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urinblåsecancer,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Urology - urothelial cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Urothelial cancer,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)urok-fli
7001 a Plass, Karin4 aut
7001 a Williamson, Sean R.u Cleveland Clinic Foundation4 aut
7001 a Gontero, Paolou University of Turin4 aut
7001 a Ribal, Maria J.u University of Barcelona4 aut
7001 a Babjuk, Markou Vienna General Hospital / University Hospital Vienna,University Hospital Motol4 aut
7001 a Black, Peter C.u University of British Columbia4 aut
7001 a Kamat, Ashish M.u University of Texas4 aut
7001 a Algaba, Ferranu Autonomous University of Barcelona4 aut
7001 a Berman, David M.u Queen's University at Kingston4 aut
7001 a Hartmann, Arndtu Friedrich-Alexander University Erlangen-Nürnberg4 aut
7001 a Masson-Lecomte, Alexandrau Université Paris Cité4 aut
7001 a Rouprêt, Morganu Pitié-Salpêtrière University Hospital4 aut
7001 a Lopez-Beltran, Antoniou Champalimaud Clinical Center,University of Córdoba, Spain4 aut
7001 a Samaratunga, Hemamaliu University of Queensland4 aut
7001 a Shariat, Shahrokh F.u Vienna General Hospital / University Hospital Vienna,University Hospital Motol4 aut
7001 a Mostafid, A. Hugh4 aut
7001 a Varma, Muraliu University Hospital of Wales4 aut
7001 a Shen, Stevenu Methodist Hospital Houston4 aut
7001 a Burger, Maximilianu Weill Cornell Medical College4 aut
7001 a Tsuzuki, Toyonoriu University of Regensburg4 aut
7001 a Palou, Joan4 aut
7001 a Compérat, Eva M.u Autonomous University of Barcelona4 aut
7001 a Sylvester, Richard J.4 aut
7001 a van der Kwast, Theo H.u Vienna General Hospital / University Hospital Vienna4 aut
7001 a van Rhijn, Bas W.G.u Antoni Van Leeuwenhoek Hospital4 aut
7001 a Downes, Michelle R.u University of Toronto,Sunnybrook Health Sciences Centre4 aut
7102 a Academic Medical Center of University of Amsterdam (AMC)b Antoni Van Leeuwenhoek Hospital4 org
7730 t European Urology Open Scienceg 52, s. 154-165q 52<154-165x 2666-1691
8564 u http://dx.doi.org/10.1016/j.euros.2023.03.019x freey FULLTEXT
8564 8u https://lup.lub.lu.se/record/3e4879e9-c0b1-4e5f-88cf-8e548957dfd9
8564 8u https://doi.org/10.1016/j.euros.2023.03.019

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