WFRF:(Allard Charlotte)
Sökning: WFRF:(Allard Charlotte) > (1999) > Summary report of t...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04731naa a2200865 4500 | |
| 001 | oai:lup.lub.lu.se:dd52b522-f26f-4f81-a0d7-cf93c0ba2804 | |
| 003 | SwePub | |
| 008 | 160401s1999 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/11151312 URI |
| 024 | 7 | a https://doi.org/10.1159/0000565232 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Stenman, U H4 aut |
| 245 | 1 0 | a Summary report of the TD-3 workshop: characterization of 83 antibodies against prostate-specific antigen |
| 264 | 1 | b Springer Science and Business Media LLC,c 1999 |
| 520 | a Twelve research groups participated in the ISOBM TD-3 Workshop in which the reactivity and specificity of 83 antibodies against prostate-specific antigen (PSA) were investigated. Using a variety of techniques including cross-inhibition assays, Western blotting, BIAcore, immunoradiometric assays and immunohistochemistry, the antibodies were categorized into six major groups which formed the basis for mapping onto two- and three-dimensional (2-D and 3-D) models of PSA. The overall findings of the TD-3 Workshop are summarized in this report. In agreement with all participating groups, three main antigenic domains were identified: free PSA-specific epitopes located in or close to amino acids 86-91; discontinuous epitopes specific for PSA without human kallikrein (hK2) cross-reactivity located at or close to amino acids 158-163; and continuous or linear epitopes shared between PSA and hK2 located close to amino acids 3-11. In addition, several minor and partly overlapping domains were also identified. Clearly, the characterization of antibodies from this workshop and the location of their epitopes on the 3-D model of PSA illustrate the importance of selecting appropriate antibody pairs for use in immunoassays. It is hoped that these findings and the epitope nomenclature described in this TD-3 Workshop are used as a standard for future evaluation of anti-PSA antibodies. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 653 | a PSA | |
| 653 | a Prostate | |
| 653 | a Antibody | |
| 653 | a Workshop | |
| 653 | a ISOBM | |
| 700 | 1 | a Paus, E4 aut |
| 700 | 1 | a Allard, W J4 aut |
| 700 | 1 | a Andersson, I4 aut |
| 700 | 1 | a Andres, C4 aut |
| 700 | 1 | a Barnett, T R4 aut |
| 700 | 1 | a Becker, Charlotteu Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)klke-cbe |
| 700 | 1 | a Belenky, A4 aut |
| 700 | 1 | a Bellanger, L4 aut |
| 700 | 1 | a Pellegrino, C M4 aut |
| 700 | 1 | a Bormer, O P4 aut |
| 700 | 1 | a Davis, G4 aut |
| 700 | 1 | a Dowell, B4 aut |
| 700 | 1 | a Grauer, L S4 aut |
| 700 | 1 | a Jette, D C4 aut |
| 700 | 1 | a Karlsson, B4 aut |
| 700 | 1 | a Kreutz, F T4 aut |
| 700 | 1 | a van der Kwast, T M4 aut |
| 700 | 1 | a Lauren, L4 aut |
| 700 | 1 | a Leinimaa, M4 aut |
| 700 | 1 | a Leinonen, J4 aut |
| 700 | 1 | a Lilja, Hansu Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)klke-hli |
| 700 | 1 | a Linton, H J4 aut |
| 700 | 1 | a Nap, M4 aut |
| 700 | 1 | a Nilsson, O4 aut |
| 700 | 1 | a Ng, P C4 aut |
| 700 | 1 | a Nustad, K4 aut |
| 700 | 1 | a Peter, A4 aut |
| 700 | 1 | a Pettersson, K4 aut |
| 700 | 1 | a Piironen, T4 aut |
| 700 | 1 | a Rapp, J4 aut |
| 700 | 1 | a Rittenhouse, H G4 aut |
| 700 | 1 | a Rye, P D4 aut |
| 700 | 1 | a Seguin, P4 aut |
| 700 | 1 | a Slota, J4 aut |
| 700 | 1 | a Sokoloff, R L4 aut |
| 700 | 1 | a Suresh, M R4 aut |
| 700 | 1 | a Very, D L4 aut |
| 700 | 1 | a Wang, T J4 aut |
| 700 | 1 | a Wigheden, Ingridu Lund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups4 aut0 (Swepub:lu)klke-iwi |
| 700 | 1 | a Wolfert, R L4 aut |
| 700 | 1 | a Yeung, K K4 aut |
| 700 | 1 | a Zhang, W-M4 aut |
| 700 | 1 | a Zhou, Z4 aut |
| 700 | 1 | a Hilgers, J4 aut |
| 710 | 2 | a Klinisk kemi, Malmöb Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t Tumor Biologyd : Springer Science and Business Media LLCg 20:Suppl. 1, s. 1-12q 20:Suppl. 1<1-12x 1423-0380x 1010-4283 |
| 856 | 4 | u http://dx.doi.org/10.1159/000056523y FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/1115131 |
| 856 | 4 8 | u https://doi.org/10.1159/000056523 |
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