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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005222naa a2200481 4500
001oai:gup.ub.gu.se/244896
003SwePub
008240528s2017 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:07701c08-cc3f-4fa2-8e06-06fdc79fecba
0247 a https://gup.ub.gu.se/publication/2448962 URI
0247 a https://doi.org/10.1002/aur.17152 DOI
0247 a https://lup.lub.lu.se/record/07701c08-cc3f-4fa2-8e06-06fdc79fecba2 URI
040 a (SwePub)gud (SwePub)lu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Beggiato, Anitau Pasteur Institute,Hôpital universitaire Robert-Debré4 aut
2451 0a Gender differences in autism spectrum disorders: Divergence among specific core symptoms.
264 c 2016-11-03
264 1b Wiley,c 2017
520 a Community-based studies have consistently shown a sex ratio heavily skewed towards males in autism spectrum disorders (ASD). The factors underlying this predominance of males are largely unknown, but the way girls score on standardized categorical diagnostic tools might account for the underrecognition of ASD in girls. Despite the existence of different norms for boys and girls with ASD on several major screening tests, the algorithm of the Autism Diagnosis Interview-Revised (ADI-R) has not been reformulated. The aim of our study was to investigate which ADI-R items discriminate between males and females, and to evaluate their weighting in the final diagnosis of autism. We then conducted discriminant analysis (DA) on a sample of 594 probands including 129 females with ASD, recruited by the Paris Autism Research International Sibpair (PARIS) Study. A replication analysis was run on an independent sample of 1716 probands including 338 females with ASD, recruited through the Autism Genetics Resource Exchange (AGRE) program. Entering the raw scores for all ADI-R items as independent variables, the DA correctly classified 78.9% of males and 72.9% of females (P<0.001) in the PARIS cohort, and 72.2% of males and 68.3% of females (P<0.0001) in the AGRE cohort. Among the items extracted by the stepwise DA, four belonged to the ADI-R algorithm used for the final diagnosis of ASD. In conclusion, several items of the ADI-R that are taken into account in the diagnosis of autism significantly differentiates between males and females. The potential gender bias thus induced may participate in the underestimation of the prevalence of ASD in females. Autism Res 2016,. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
653 a autism diagnosis interview-revised; autism spectrum disorders; gender; sex
653 a autism spectrum disorders; sex; gender; autism diagnosis interview-revised
7001 a Peyre, Hugou Hôpital universitaire Robert-Debré4 aut
7001 a Maruani, Annau Pasteur Institute,Hôpital universitaire Robert-Debré4 aut
7001 a Scheid, Isabelleu Hôpital universitaire Robert-Debré,Pasteur Institute,Fondation FondaMental4 aut
7001 a Råstam, Mariau Lund University,Lunds universitet,Barn- och ungdomspsykiatri,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Utvecklingsrelaterade störningar, affektiv sjukdom och ångestsyndrom i barn- och ungdomspsykiatri,Forskargrupper vid Lunds universitet,Child and Adolescent Psychiatry,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Disorders in clinical child and adolescent psychiatry,Lund University Research Groups4 aut0 (Swepub:lu)med-mr_
7001 a Amsellem, Frederiqueu Pasteur Institute,Hôpital universitaire Robert-Debré4 aut
7001 a Gillberg, I Carina,d 1949u University of Gothenburg,Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre4 aut0 (Swepub:gu)xgillc
7001 a Leboyer, Marionu Fondation FondaMental,Mondor Institute of Biomedical Research (Inserm U955),Henri Mondor Hospital4 aut
7001 a Bourgeron, Thomasu Paris Diderot University,Pasteur Institute4 aut0 (Swepub:gu)xbouth
7001 a Gillberg, Christopher,d 1950u University of Gothenburg,Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre,University College London4 aut0 (Swepub:gu)xgilch
7001 a Delorme, Richardu Paris Diderot University,Hôpital universitaire Robert-Debré,Pasteur Institute,Fondation FondaMental4 aut
7102 a Pasteur Instituteb Hôpital universitaire Robert-Debré4 org
7730 t Autism research : official journal of the International Society for Autism Researchd : Wileyg 10:4, s. 680-689q 10:4<680-689x 1939-3806x 1939-3792
7730 t Autism Researchd : Wileyg 10:4, s. 680-689q 10:4<680-689x 1939-3792
8564 u http://dx.doi.org/10.1002/aur.1715y FULLTEXT
8564 8u https://gup.ub.gu.se/publication/244896
8564 8u https://doi.org/10.1002/aur.1715
8564 8u https://lup.lub.lu.se/record/07701c08-cc3f-4fa2-8e06-06fdc79fecba

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