Sökning: WFRF:(Baldini Matteo) > Detecting the vulne...
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000 | 05312naa a2200709 4500 | |
001 | oai:lup.lub.lu.se:898f7f36-b640-458f-a3a8-5489ea4d5ce3 | |
003 | SwePub | |
008 | 221010s2022 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/898f7f36-b640-458f-a3a8-5489ea4d5ce32 URI |
024 | 7 | a https://doi.org/10.2459/JCM.00000000000013142 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Gargani, Luna4 aut |
245 | 1 0 | a Detecting the vulnerable carotid plaque : The Carotid Artery Multimodality imaging Prognostic study design |
264 | 1 | c 2022 |
300 | a 8 s. | |
520 | a BackgroundCarotid artery disease is highly prevalent and a main cause of ischemic stroke and vascular dementia. There is a paucity of information on predictors of serious vascular events. Besides percentage diameter stenosis, international guidelines also recommend the evaluation of qualitative characteristics of carotid artery disease as a guide to treatment, but with no agreement on which qualitative features to assess. This inadequate knowledge leads to a poor ability to identify patients at risk, dispersion of medical resources, and unproven use of expensive and resource-consuming techniques, such as magnetic resonance imaging, positron emission tomography, and computed tomography.ObjectivesThe Carotid Artery Multimodality imaging Prognostic (CAMP) study will: prospectively determine the best predictors of silent and overt ischemic stroke and vascular dementia in patients with asymptomatic subcritical carotid artery disease by identifying the noninvasive diagnostic features of the 'vulnerable carotid plaque'; assess whether 'smart' use of low-cost diagnostic methods such as ultrasound-based evaluations may yield at least the same level of prospective information as more expensive techniques.Study designWe will compare the prognostic/predictive value of all proposed techniques with regard to silent or clinically manifest ischemic stroke and vascular dementia. The study will include ≥300 patients with asymptomatic, unilateral, intermediate degree (40-60% diameter) common or internal carotid artery stenosis detected at carotid ultrasound, with a 2-year follow-up. The study design has been registered on Clinicaltrial.gov on December 17, 2020 (ID number NCT04679727). | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a atherosclerosis | |
653 | a carotid artery disease | |
653 | a carotid artery plaque | |
653 | a carotid ultrasound | |
653 | a magnetic resonance imaging | |
653 | a stroke | |
653 | a vascular dementia | |
653 | a vascular imaging | |
700 | 1 | a Baldini, Matteou University of Pisa4 aut |
700 | 1 | a Berchiolli, Raffaellau University of Pisa4 aut |
700 | 1 | a Bort, Ida Rebeccau University of Pisa4 aut |
700 | 1 | a Casolo, Giancarlo4 aut |
700 | 1 | a Chiappino, Dante4 aut |
700 | 1 | a Cosottini, Mircou University of Pisa4 aut |
700 | 1 | a D'Angelo, Gennaro4 aut |
700 | 1 | a De Santis, Mariellau University of Pisa4 aut |
700 | 1 | a Erba, Paolau University Medical Center Groningen,University of Pisa4 aut |
700 | 1 | a Fabiani, Iacopo4 aut |
700 | 1 | a Fabiani, Plinio4 aut |
700 | 1 | a Gabbriellini, Ilariau University of Pisa4 aut |
700 | 1 | a Galeotti, Gian Giacomou University of Pisa4 aut |
700 | 1 | a Ghicopulos, Ireneu University of Pisa4 aut |
700 | 1 | a Goncalves, Isabelu Lund University,Lunds universitet,Kardiovaskulär forskning - translationella studier,Forskargrupper vid Lunds universitet,Cardiovascular Research - Translational Studies,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-igo |
700 | 1 | a Lapi, Simoneu University Hospital of Pisa4 aut |
700 | 1 | a Masini, Gabrieleu University of Pisa4 aut |
700 | 1 | a Morizzo, Carmelau University of Pisa4 aut |
700 | 1 | a Napoli, Viniciou University Hospital of Pisa4 aut |
700 | 1 | a Nilsson, Janu Lund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-jni |
700 | 1 | a Orlandi, Giovanniu University of Pisa4 aut |
700 | 1 | a Palombo, Carlou University of Pisa4 aut |
700 | 1 | a Pieraccini, Francesco4 aut |
700 | 1 | a Ricci, Stefanou University of Florence4 aut |
700 | 1 | a Siciliano, Gabrieleu University of Pisa4 aut |
700 | 1 | a Slart, Riemer H.J.A.u University of Twente,University Medical Center Groningen4 aut |
700 | 1 | a De Caterina, Raffaeleu University of Pisa4 aut |
710 | 2 | a University of Pisab University Medical Center Groningen4 org |
773 | 0 | t Journal of Cardiovascular Medicineg 23:7, s. 466-473q 23:7<466-473x 1558-2027 |
856 | 4 | u http://dx.doi.org/10.2459/JCM.0000000000001314y FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/898f7f36-b640-458f-a3a8-5489ea4d5ce3 |
856 | 4 8 | u https://doi.org/10.2459/JCM.0000000000001314 |
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