Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention-Radial Versus Femoral Access (from the OCEAN RACE Trial)

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Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention-Radial Versus Femoral Access (from the OCEAN RACE Trial)

Koltowski, Lukasz (author): 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland

Koltowska-Häggström, Maria, 1957- (author): Uppsala universitet,Institutionen för kvinnors och barns hälsa,Barnendokrinologisk forskning/Gustafsson

Filipiak, Krzysztof Jerzy (author): 1st Department of Cardiology, Medical University of Warsaw, Poland

Kochman, Janusz (author): 1st Department of Cardiology, Medical University of Warsaw, Poland

Golicki, Dominik (author): Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland

Pietrasik, Arkadiusz (author): 1st Department of Cardiology, Medical University of Warsaw, Poland

Huczek, Zenon (author): 1st Department of Cardiology, Medical University of Warsaw, Poland

Balsam, Pawel (author): 1st Department of Cardiology, Medical University of Warsaw, Poland

Scibisz, Anna (author): 1st Department of Cardiology, Medical University of Warsaw, Poland

Opolski, Grzegorz (author): 1st Department of Cardiology, Medical University of Warsaw, Poland

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Elsevier BV, 2014
2014
English.
In: American Journal of Cardiology. - : Elsevier BV. - 0002-9149 .- 1879-1913. ; 114:4, s. 516-521

Related links:: https://urn.kb.se/re...; show more...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Numerous studies have compared transradial (TR) versus transfemoral (TF) access for percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction. These studies have focused on clinical efficacy and safety; yet little is known about the effect of the vessel access on the health-related quality of life (HRQoL). In the present study, patients were randomly assigned to TR (n = 52) or TF (n = 51) access groups. Generic (EQ-5D-3L) and cardiac-specific (Quality of Life Index and MacNew) tools were used to assess HRQoL before PCI and 2 hours and 4 days after PCI. Baseline HRQoL was comparable in both groups and improved after PCI. The mean +/- SD EQ-5D-3L health utility score 2 hours after PCI was 0.46 +/- 0.291 and was higher in the TR group (TR: 0.60 +/- 0.299 versus TF: 0.32 +/- 0.283, p <0.001). Patients in the TR group reported fewer problems with mobility (TR: 71.7% vs TF: 94.4%, p <0.01) and self-care (TR: 62.5% vs TF: 97.2%, p <0.001). At day 4, fewer patients reported problems with anxiety and/or depression in the TR group than in the TF group (TR: 42.9% vs TF: 75.0%, p <0.001); no differences between groups in other measures were observed (Quality of Life Index and MacNew). The N-terminal of the prohormone brain natriuretic peptide levels were inversely correlated with EQ-5D-3L visual analog scale (r = -0.348, p <0.05) and EQ-5D-3L health utility score (r = -0.322, p <0.05). There was a correlation between in-hospital mortality and 2 MacNew domains: physical (r = -0.329, p <0.05) and emotional (r = -0.374, p <0.01). In conclusion, radial access should be the preferred approach in patients with ST-segment elevation myocardial infarction undergoing PCI when considering HRQoL. Radial access is associated with fewer problems with mobility and self-care and better psychological outcome after PCI.

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By the author/editor: Koltowski, Lukas ...; Koltowska-Häggst ...; Filipiak, Krzysz ...; Kochman, Janusz; Golicki, Dominik; Pietrasik, Arkad ...; show more...; Huczek, Zenon; Balsam, Pawel; Scibisz, Anna; Opolski, Grzegor ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

Articles in the publication: American Journal ...

By the university: Uppsala University

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Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention-Radial Versus Femoral Access (from the OCEAN RACE Trial)

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