Bone Phenotyping Approaches in Human, Mice and Zebrafish – Expert Overview of the EU Cost Action GEMSTONE (“GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork”)

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Fältnamn	Indikatorer	Metadata
000		05415naa a2200805 4500
001		oai:lup.lub.lu.se:9adf4e84-655e-4bc4-870b-7ccca80bd107
003		SwePub
008		220126s2021 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:gup.ub.gu.se/311959
024	7	a https://lup.lub.lu.se/record/9adf4e84-655e-4bc4-870b-7ccca80bd1072 URI
024	7	a https://doi.org/10.3389/fendo.2021.7207282 DOI
024	7	a https://gup.ub.gu.se/publication/3119592 URI
040		a (SwePub)lud (SwePub)gu
041		a engb eng
042		9 SwePub
072	7	a for2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Foessl, Inesu Medical University of Graz4 aut
245	1 0	a Bone Phenotyping Approaches in Human, Mice and Zebrafish – Expert Overview of the EU Cost Action GEMSTONE (“GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork”)
264		c 2021-12-01
264	1	b Frontiers Media SA,c 2021
520		a A synoptic overview of scientific methods applied in bone and associated research fields across species has yet to be published. Experts from the EU Cost Action GEMSTONE (“GEnomics of MusculoSkeletal Traits translational Network”) Working Group 2 present an overview of the routine techniques as well as clinical and research approaches employed to characterize bone phenotypes in humans and selected animal models (mice and zebrafish) of health and disease. The goal is consolidation of knowledge and a map for future research. This expert paper provides a comprehensive overview of state-of-the-art technologies to investigate bone properties in humans and animals – including their strengths and weaknesses. New research methodologies are outlined and future strategies are discussed to combine phenotypic with rapidly developing –omics data in order to advance musculoskeletal research and move towards “personalised medicine”.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
653		a animal models
653		a bone and skeletal diseases
653		a COST
653		a GEMSTONE
653		a imaging
653		a phenotyping
700	1	a Bassett, J. H.Duncanu Imperial College London4 aut
700	1	a Bjørnerem, Åshildu Oslo university hospital,UiT The Arctic University of Norway, Tromsø4 aut
700	1	a Busse, Björnu University Medical Center Hamburg-Eppendorf4 aut
700	1	a Calado, Ângelou University of Lisbon4 aut
700	1	a Chavassieux, Pascaleu University of Lyon4 aut
700	1	a Christou, Mariau University of Ioannina4 aut
700	1	a Douni, Eleniu Biomedical Sciences Research Center - Alexander Fleming,Agricultural University of Athens4 aut
700	1	a Fiedler, Imke A.K.u University Medical Center Hamburg-Eppendorf4 aut
700	1	a Fonseca, João Euricou University of Lisbon4 aut
700	1	a Hassler, Evau Medical University of Graz4 aut
700	1	a Högler, Wolfgangu Johannes-Kepler-University of Linz4 aut
700	1	a Kague, Erikau University of Bristol4 aut
700	1	a Karasik, Davidu Bar-Ilan University4 aut
700	1	a Khashayar, Patricia4 aut
700	1	a Langdahl, Bente L.u Aarhus University Hospital4 aut
700	1	a Leitch, Victoria D.u RMIT University4 aut
700	1	a Lopes, Philippeu Lund University4 aut
700	1	a Markozannes, Georgiosu University of Ioannina4 aut
700	1	a McGuigan, Fiona E.A.u Lund University,Lunds universitet,Ortopedi,Forskargrupper vid Lunds universitet,Orthopedics,Lund University Research Groups4 aut0 (Swepub:lu)med-fam
700	1	a Medina-Gomez, Carolinau Erasmus University Medical Center4 aut
700	1	a Ntzani, Evangeliau University of Ioannina,Brown University4 aut
700	1	a Oei, Lingu Sahlgrenska Academy4 aut
700	1	a Ohlsson, Claes,d 1965u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xohlcl
700	1	a Szulc, Pawelu University of Lyon4 aut
700	1	a Tobias, Jonathan H.u University of Bristol4 aut
700	1	a Trajanoska, Katerinau Erasmus University Medical Center4 aut
700	1	a Tuzun, Şansınu Istanbul University4 aut
700	1	a Valjevac, Aminau University of Sarajevo4 aut
700	1	a van Rietbergen, Bertu Eindhoven University of Technology4 aut
700	1	a Williams, Graham R.u Imperial College London4 aut
700	1	a Zekic, Tatjanau University Hospital Rijeka4 aut
700	1	a Rivadeneira, Fernandou Erasmus University Medical Center4 aut
700	1	a Obermayer-Pietsch, Barbarau Medical University of Graz4 aut
710	2	a Medical University of Grazb Imperial College London4 org
773	0	t Frontiers in Endocrinologyd : Frontiers Media SAg 12q 12x 1664-2392
856	4	u http://dx.doi.org/10.3389/fendo.2021.720728x freey FULLTEXT
856	4	u https://www.frontiersin.org/articles/10.3389/fendo.2021.720728/pdf
856	4 8	u https://lup.lub.lu.se/record/9adf4e84-655e-4bc4-870b-7ccca80bd107
856	4 8	u https://doi.org/10.3389/fendo.2021.720728
856	4 8	u https://gup.ub.gu.se/publication/311959

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