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Mammographic density : Comparison of visual assessment with fully automatic calculation on a multivendor dataset

Sacchetto, Daniela (author)
Morra, Lia (author)
Agliozzo, Silvano (author)
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Bernardi, Daniela (author)
Björklund, Tomas (author)
KTH,Skolan för teknik och hälsa (STH)
Brancato, Beniamino (author)
Bravetti, Patrizia (author)
Carbonaro, Luca A. (author)
Correale, Loredana (author)
Fanto, Carmen (author)
Favettini, Elisabetta (author)
Martincich, Laura (author)
Milanesio, Luisella (author)
Mombelloni, Sara (author)
Monetti, Francesco (author)
Morrone, Doralba (author)
Pellegrini, Marco (author)
Pesce, Barbara (author)
Petrillo, Antonella (author)
Saguatti, Gianni (author)
Stevanin, Carmen (author)
Trimboli, Rubina M. (author)
Tuttobene, Paola (author)
Valentini, Marvi (author)
Marra, Vincenzo (author)
Frigerio, Alfonso (author)
Bert, Alberto (author)
Sardanelli, Francesco (author)
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 (creator_code:org_t)
2015-05-01
2016
English.
In: European Radiology. - : Springer. - 0938-7994 .- 1432-1084. ; 26:1, s. 175-183
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • To compare breast density (BD) assessment provided by an automated BD evaluator (ABDE) with that provided by a panel of experienced breast radiologists, on a multivendor dataset. Twenty-one radiologists assessed 613 screening/diagnostic digital mammograms from nine centers and six different vendors, using the BI-RADS a, b, c, and d density classification. The same mammograms were also evaluated by an ABDE providing the ratio between fibroglandular and total breast area on a continuous scale and, automatically, the BI-RADS score. A panel majority report (PMR) was used as reference standard. Agreement (kappa) and accuracy (proportion of cases correctly classified) were calculated for binary (BI-RADS a-b versus c-d) and 4-class classification. While the agreement of individual radiologists with the PMR ranged from kappa = 0.483 to kappa = 0.885, the ABDE correctly classified 563/613 mammograms (92 %). A substantial agreement for binary classification was found for individual reader pairs (kappa = 0.620, standard deviation [SD] = 0.140), individual versus PMR (kappa = 0.736, SD = 0.117), and individual versus ABDE (kappa = 0.674, SD = 0.095). Agreement between ABDE and PMR was almost perfect (kappa = 0.831). The ABDE showed an almost perfect agreement with a 21-radiologist panel in binary BD classification on a multivendor dataset, earning a chance as a reproducible alternative to visual evaluation. aEuro cent Individual BD assessment differs from PMR with kappa as low as 0.483. aEuro cent An ABDE correctly classified 92 % of mammograms with almost perfect agreement (kappa = 0.831). aEuro cent An ABDE can be a valid alternative to subjective BD assessment.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Keyword

Breast density
Digital mammography
Automated system
BI-RADS density classification
Multireader/multivendor

Publication and Content Type

ref (subject category)
art (subject category)

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