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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004535naa a2200577 4500
001oai:DiVA.org:umu-121211
003SwePub
008160530s2015 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-365947
009oai:prod.swepub.kib.ki.se:132076921
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1212112 URI
0247 a https://doi.org/10.1007/s00345-014-1464-52 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3659472 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1320769212 URI
040 a (SwePub)umud (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Grotta, Alessandra4 aut
2451 0a Physical activity and body mass index as predictors of prostate cancer risk
264 c 2015-01-04
264 1b Springer Science and Business Media LLC,c 2015
338 a print2 rdacarrier
520 a PURPOSE: Physical activity and body mass index (BMI) are involved in prostate cancer etiology; possible biologic mechanisms include their effects on hormonal levels. Our aim was to investigate the relationship between physical activity, obesity, and prostate cancer.METHODS: We followed a cohort of 13,109 Swedish men for 13 years and investigated the association of self-reported physical activity and BMI at baseline with prostate cancer incidence. We further analyzed whether BMI could modulate effects of physical activity. Occupational, recreational, and total physical activity were analyzed in relation to overall, localized, and advanced prostate cancer.RESULTS: During the study follow-up, we observed a total of 904 cases of prostate cancer (429 localized, 407 advanced, and 68 unclassified). High levels of occupational physical activity were associated with a nonsignificantly decreased risk of overall (HR 0.81, 95 % CI 0.61-1.07), localized (HR 0.75, 95 % CI 0.51-1.12), and advanced (HR 0.85, 95 % CI 0.55-1.31) prostate cancer. We found no association between high BMI and risk of prostate cancer incidence: We observed, however, a significant interaction between BMI and leisure physical activity.CONCLUSION: No association was confirmed between total physical activity and localized or advanced prostate cancer. The highest, relative to the lowest, level of occupational physical activity tended to be linked to a lower risk of prostate cancer, with a suggested dose-response relationship. We found no association between high BMI and risk of prostate cancer incidence; however, our analyses suggested an interaction between BMI and physical activity during recreational time that merits further investigation in future studies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a Physical activity
653 a Body mass index
653 a Prostate cancer
653 a Cohort study
653 a Epidemiology
7001 a Bottai, Matteou Karolinska Institutet4 aut
7001 a Adami, Hans-Olovu Karolinska Institutet4 aut
7001 a Adams, Swann Arp4 aut
7001 a Akre, Olofu Karolinska Institutet4 aut
7001 a Blair, Steven Noel4 aut
7001 a Mariosa, Danielau Karolinska Institutet4 aut
7001 a Nyrén, Olof4 aut
7001 a Ye, Weiminu Karolinska Institutet4 aut
7001 a Stattin, Päru Umeå universitet,Urologi och andrologi,Surgery and Perioperative Sciences, Urology and AndrologyUmeå University HospitalUmeåSweden4 aut0 (Swepub:uu)parst892
7001 a Bellocco, Rinou Karolinska Institutet4 aut
7001 a Trolle Lagerros, Ylvau Karolinska Institutet4 aut
7102 a Karolinska Institutetb Urologi och andrologi4 org
7730 t World journal of urologyd : Springer Science and Business Media LLCg 33:10, s. 1495-1502q 33:10<1495-1502x 0724-4983x 1433-8726
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121211
8564 8u https://doi.org/10.1007/s00345-014-1464-5
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-365947
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:132076921

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