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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 13277naa a2201777 4500 | |
| 001 | oai:DiVA.org:liu-187431 | |
| 003 | SwePub | |
| 008 | 220823s2022 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:150208354 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1874312 URI |
| 024 | 7 | a https://doi.org/10.1007/s00270-022-03176-12 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1502083542 URI |
| 040 | a (SwePub)liud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Korenblik, R.u Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands4 aut |
| 245 | 1 0 | a Dragon 1 Protocol Manuscript :b Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy |
| 264 | c 2022-07-05 | |
| 264 | 1 | b Springer,c 2022 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Funding Agencies|Dutch Cancer Society (KWF); Abbott Laboratories; Maastricht University; Maastricht University Medical Center; NIHR; Guerbet | |
| 520 | a Study Purpose The DRAGON 1 trial aims to assess training, implementation, safety and feasibility of combined portal- and hepatic-vein embolization (PVE/HVE) to accelerate future liver remnant (FLR) hypertrophy in patients with borderline resectable colorectal cancer liver metastases. Methods The DRAGON 1 trial is a worldwide multicenter prospective single arm trial. The primary endpoint is a composite of the safety of PVE/HVE, 90-day mortality, and one year accrual monitoring of each participating center. Secondary endpoints include: feasibility of resection, the used PVE and HVE techniques, FLR-hypertrophy, liver function (subset of centers), overall survival, and disease-free survival. All complications after the PVE/HVE procedure are documented. Liver volumes will be measured at week 1 and if applicable at week 3 and 6 after PVE/HVE and follow-up visits will be held at 1, 3, 6, and 12 months after the resection. Results Not applicable. Conclusion DRAGON 1 is a prospective trial to assess the safety and feasibility of PVE/HVE. Participating study centers will be trained, and procedures standardized using Work Instructions (WI) to prepare for the DRAGON 2 randomized controlled trial. Outcomes should reveal the accrual potential of centers, safety profile of combined PVE/HVE and the effect of FLR-hypertrophy induction by PVE/HVE in patients with CRLM and a small FLR. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 653 | a Colorectal cancer liver metastases (CRLM); Portal vein embolization (PVE); Hepatic vein embolization (HVE); Combined portal- and hepatic vein embolization (PVE; HVE); Liver hypertrophy; Future liver remnant (FLR) | |
| 700 | 1 | a Olij, B.u Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands4 aut |
| 700 | 1 | a Aldrighetti, L. A.u Osped San Raffaele, Italy4 aut |
| 700 | 1 | a Abu Hilal, M.u Fdn Poliambulanza, Italy,Oxford Univ Hosp NHS, England,Univ Hosp Heidelberg, Germany,Queen Elizabeth Hosp Birmingham NHS, England,Erasmus MC, Netherlands,Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany4 aut |
| 700 | 1 | a Ahle, Margareta,d 1966-u Region Östergötland, Röntgenkliniken i Linköping4 aut0 (Swepub:liu)marah33 |
| 700 | 1 | a Arslan, B.u Rush Univ Med Ctr, IL USA,Cantonal Hosp Winterthur, Switzerland4 aut |
| 700 | 1 | a van Baardewijk, L. J.u Maxima Med Ctr, Netherlands,Hop Erasme, Belgium4 aut |
| 700 | 1 | a Baclija, Iu Clin Favoriten, Austria4 aut |
| 700 | 1 | a Bent, C.u Royal Bournemouth & Christchurch Hosp, England; Royal Bournemouth & Christchurch Hosp, England,Aintree Univ Hosp NHS Fdn Trust, England4 aut |
| 700 | 1 | a Bertrand, C. L.u CHU UCLouvain Namur, Belgium4 aut |
| 700 | 1 | a Björnsson, Bergthor,d 1975-u Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US4 aut0 (Swepub:liu)berbj34 |
| 700 | 1 | a de Boer, M. T.u Univ Med Ctr Groningen, Netherlands4 aut |
| 700 | 1 | a de Boer, S. W.u Maastricht Univ Med Ctr, Netherlands4 aut |
| 700 | 1 | a Bokkers, R. P. H.u Univ Med Ctr Groningen, Netherlands,Kings Coll Hosp NHS, England4 aut |
| 700 | 1 | a Rinkes, I. H. M. Borelu Univ Med Ctr Utrecht, Netherlands,St Clara Spital, Switzerland,Gemelli Univ Hosp, Italy,Amsterdam Univ Med Ctr Locat VU, Netherlands4 aut |
| 700 | 1 | a Breitenstein, S.u Cantonal Hosp Winterthur, Switzerland4 aut |
| 700 | 1 | a Bruijnen, R. C. G.u Univ Med Ctr Utrecht, Netherlands,Royal Prince Alfred Hosp, Australia4 aut |
| 700 | 1 | a Bruners, P.u Univ Hosp Aachen, Germany4 aut |
| 700 | 1 | a Camacho, J. C.u Mem Sloan Kettering Canc Ctr, NY 10021 USA,Western Hlth Footscray, Australia,Univ Hosp Bonn, Germany,Rush Univ Med Ctr, IL USA4 aut |
| 700 | 1 | a Cappelli, A.u St Orsola Malpighi Hosp, Italy4 aut |
| 700 | 1 | a Carling, U.u Univ Hosp Oslo, Norway4 aut |
| 700 | 1 | a Chan, B. K. Y.u Aintree Univ Hosp NHS Fdn Trust, England4 aut |
| 700 | 1 | a Chang, D. H.u Univ Hosp Heidelberg, Germany,Univ Hosp Aachen, Germany4 aut |
| 700 | 1 | a Choi, J.u Western Hlth Footscray, Australia4 aut |
| 700 | 1 | a Codina Font, J.u Univ Hosp Dr Josep Trueta Girona, Spain4 aut |
| 700 | 1 | a Crawford, M.u Royal Prince Alfred Hosp, Australia,Yale Sch Med, CT USA,Univ Hosp Bonn, Germany4 aut |
| 700 | 1 | a Croagh, D.u Monash Hlth, Australia,Maastricht Univ Med Ctr, Netherlands4 aut |
| 700 | 1 | a Cugat, E.u Univ Hosp Germans Trias I Pujol, Spain4 aut |
| 700 | 1 | a Davis, R.u Aintree Univ Hosp NHS Fdn Trust, England,Royal Free Hosp NHS, England4 aut |
| 700 | 1 | a De Boo, D. W.u Monash Hlth, Australia4 aut |
| 700 | 1 | a De Cobelli, F.u Osped San Raffaele, Italy,Hosp Clin Barcelona, Spain4 aut |
| 700 | 1 | a De Wispelaere, J. F.u CHU UCLouvain Namur, Belgium4 aut |
| 700 | 1 | a van Delden, O. M.u Amsterdam Univ Med Ctr Locat AMC, Netherlands,Karolinska Univ Hosp, Sweden4 aut |
| 700 | 1 | a Delle, M.u Karolinska Univ Hosp, Sweden4 aut |
| 700 | 1 | a Detry, O.u CHU Liege, Belgium4 aut |
| 700 | 1 | a Dili, A.u CHU UCLouvain Namur, Belgium4 aut |
| 700 | 1 | a Erdmann, J. Iu Amsterdam Univ Med Ctr Locat AMC, Netherlands,Osped Maggiore Bologna, Italy4 aut |
| 700 | 1 | a Fisher, O.u Royal Prince Alfred Hosp, Australia4 aut |
| 700 | 1 | a Fondevila, C.u Hosp Clin Barcelona, Spain4 aut |
| 700 | 1 | a Fretland, A.u Univ Hosp Oslo, Norway4 aut |
| 700 | 1 | a Garcia Borobia, F.u Hosp Parc Tauli Sabadell, Spain4 aut |
| 700 | 1 | a Gelabert, A.u Hosp Parc Tauli Sabadell, Spain; Univ Hosp Mutua Terassa, Spain,Klinikum Saarbrucken gGmbH, Germany4 aut |
| 700 | 1 | a Gerard, L.u CHU Liege, Belgium,Maxima Med Ctr, Netherlands4 aut |
| 700 | 1 | a Giuliante, F.u Gemelli Univ Hosp Rome, Italy,Clarunis Univ Hosp, Switzerland4 aut |
| 700 | 1 | a Gobardhan, P. D.u Amphia, Netherlands4 aut |
| 700 | 1 | a Gomez, F.u Hosp Clin Barcelona, Spain4 aut |
| 700 | 1 | a Grunberger, T.u Clin Favoriten, Austria4 aut |
| 700 | 1 | a Grunhagen, D. J.u Erasmus MC, Netherlands4 aut |
| 700 | 1 | a Guitart, J.u Univ Hosp Mutua Terassa, Spain4 aut |
| 700 | 1 | a Hagendoorn, J.u Univ Med Ctr Utrecht, Netherlands4 aut |
| 700 | 1 | a Heil, J.u Univ Hosp Frankfurt, Germany4 aut |
| 700 | 1 | a Heise, D.u Univ Hosp Aachen, Germany4 aut |
| 700 | 1 | a Herrero, E.u Univ Hosp Mutua Terassa, Spain4 aut |
| 700 | 1 | a Hess, G. F.u Clarunis Univ Hosp, Switzerland4 aut |
| 700 | 1 | a Hoffmann, M. H.u St Clara Spital, Switzerland4 aut |
| 700 | 1 | a Iezzi, R.u Gemelli Univ Hosp, Italy4 aut |
| 700 | 1 | a Imani, F.u Amphia, Netherlands4 aut |
| 700 | 1 | a Nguyen, J.u Western Hlth Footscray, Australia,Univ Hosp Southampton NHS, England4 aut |
| 700 | 1 | a Jovine, E.u Osped Maggiore Bologna, Italy4 aut |
| 700 | 1 | a Kalff, J. C.u Univ Hosp Bonn, Germany4 aut |
| 700 | 1 | a Kazemier, G.u Amsterdam Univ Med Ctr Locat VU, Netherlands4 aut |
| 700 | 1 | a Kingham, T. P.u Mem Sloan Kettering Canc Ctr, NY 10021 USA4 aut |
| 700 | 1 | a Kleeff, J.u Univ Hosp Halle Saale, Germany4 aut |
| 700 | 1 | a Kollmar, O.u Clarunis Univ Hosp, Switzerland4 aut |
| 700 | 1 | a Leclercq, W. K. G.u Maxima Med Ctr, Netherlands4 aut |
| 700 | 1 | a Lopez Ben, S.u Univ Hosp Dr Josep Truetade Girona, Spain,Univ Hosp Miguel Servet, Spain4 aut |
| 700 | 1 | a Lucidi, Vu Hop Erasme, Belgium4 aut |
| 700 | 1 | a MacDonald, A.u Oxford Univ Hosp NHS, England4 aut |
| 700 | 1 | a Madoff, D. C.u Yale Sch Med, CT USA4 aut |
| 700 | 1 | a Manekeller, S.u Univ Hosp Bonn, Germany,IRCCS Azienda Osped Univ Bologna, Italy,Univ Med Ctr Utrecht, Netherlands4 aut |
| 700 | 1 | a Martel, G.u Ottawa Hosp, Canada4 aut |
| 700 | 1 | a Mehrabi, A.u Univ Hosp Heidelberg, Germany4 aut |
| 700 | 1 | a Mehrzad, H.u Queen Elizabeth Hosp Birmingham NHS, England4 aut |
| 700 | 1 | a Meijerink, M. R.u Amsterdam Univ Med Ctr Locat VU, Netherlands,Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany4 aut |
| 700 | 1 | a Menon, K.u Kings Coll Hosp NHS, England4 aut |
| 700 | 1 | a Metrakos, P.u McGill Univ Hlth Ctr, Canada4 aut |
| 700 | 1 | a Meyer, C.u Univ Hosp Bonn, Germany4 aut |
| 700 | 1 | a Moelker, A.u Erasmus MC, Netherlands4 aut |
| 700 | 1 | a Modi, S.u Univ Hosp Southampton NHS, England4 aut |
| 700 | 1 | a Montanari, N.u Osped Maggiore Bologna, Italy4 aut |
| 700 | 1 | a Navines, J.u Univ Hosp Germans Trias I Pujol, Spain4 aut |
| 700 | 1 | a Neumann, U. P.u Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany4 aut |
| 700 | 1 | a Peddu, P.u Kings Coll Hosp NHS, England,Queen Elizabeth Hosp Birmingham NHS, England4 aut |
| 700 | 1 | a Primrose, J. N.u Univ Hosp Southampton NHS, England4 aut |
| 700 | 1 | a Qu, X.u Fundan Univ, Peoples R China4 aut |
| 700 | 1 | a Raptis, D.u Royal Free Hosp NHS, England4 aut |
| 700 | 1 | a Ratti, F.u Osped San Raffaele, Italy4 aut |
| 700 | 1 | a Ridouani, F.u Mem Sloan Kettering Canc Ctr, NY 10021 USA4 aut |
| 700 | 1 | a Rogan, C.u Royal Prince Alfred Hosp, Australia4 aut |
| 700 | 1 | a Ronellenfitsch, U.u Univ Hosp Halle Saale, Germany4 aut |
| 700 | 1 | a Ryan, S.u Ottawa Hosp, Canada4 aut |
| 700 | 1 | a Sallemi, C.u Fdn Poliambulanza, Italy4 aut |
| 700 | 1 | a Sampere Moragues, J.u Univ Hosp Germans Trias I Pujol, Spain4 aut |
| 700 | 1 | a Sandström, Per A,d 1965-u Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US4 aut0 (Swepub:liu)persa07 |
| 700 | 1 | a Sarria, L.u Univ Hosp Miguel Servet, Spain4 aut |
| 700 | 1 | a Schnitzbauer, A.u Univ Hosp Frankfurt, Germany,Newcastle Upon Tyne Hosp NHS, England4 aut |
| 700 | 1 | a Serenari, M.u IRCCS Azienda Osped Univ Bologna, Italy4 aut |
| 700 | 1 | a Serrablo, A.u Univ Hosp Miguel Servet, Spain4 aut |
| 700 | 1 | a Smits, M. L. J.u Univ Med Ctr Utrecht, Netherlands4 aut |
| 700 | 1 | a Sparrelid, E.u Karolinska Institutet,Karolinska Univ Hosp, Sweden4 aut |
| 700 | 1 | a Spuntrup, E.u Klinikum Saarbrucken gGmbH, Germany4 aut |
| 700 | 1 | a Stavrou, G. A.u Klinikum Saarbrucken gGmbH, Germany4 aut |
| 700 | 1 | a Sutcliffe, R. P.u Queen Elizabeth Hosp Birmingham NHS, England4 aut |
| 700 | 1 | a Tancredi, Iu Hop Erasme, Belgium4 aut |
| 700 | 1 | a Tasse, J. C.u Rush Univ Med Ctr, IL USA4 aut |
| 700 | 1 | a Udupa, Vu Oxford Univ Hosp NHS, England4 aut |
| 700 | 1 | a Valenti, D.u McGill Univ Hlth Ctr, Canada4 aut |
| 700 | 1 | a Fundora, Y.u Hosp Clin Barcelona, Spain4 aut |
| 700 | 1 | a Vogl, T. J.u Univ Hosp Frankfurt, Germany4 aut |
| 700 | 1 | a Wang, X.u Fundan Univ, Peoples R China4 aut |
| 700 | 1 | a White, S. A.u Newcastle Upon Tyne Hosp NHS, England4 aut |
| 700 | 1 | a Wohlgemuth, W. A.u Univ Hosp Halle Saale, Germany4 aut |
| 700 | 1 | a Yu, D.u Royal Free Hosp NHS, England4 aut |
| 700 | 1 | a Zijlstra, I. A. J.u Amsterdam Univ Med Ctr Locat VU, Netherlands4 aut |
| 700 | 1 | a Binkert, C. A.u Cantonal Hosp Winterthur, Switzerland4 aut |
| 700 | 1 | a Bemelmans, M. H. A.u Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany4 aut |
| 700 | 1 | a van der Leij, C.u Maastricht Univ Med Ctr, Netherlands4 aut |
| 700 | 1 | a Schadde, E.u Cantonal Hosp Winterthur, Switzerland; Rush Univ Med Ctr Chicago, IL USA4 aut |
| 700 | 1 | a van Dam, R. M.u Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany4 aut |
| 710 | 2 | a Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlandsb Osped San Raffaele, Italy4 org |
| 773 | 0 | t Cardiovascular and Interventional Radiologyd : Springerg 45, s. 1391-1398q 45<1391-1398x 0174-1551x 1432-086X |
| 856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1689539/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-187431 |
| 856 | 4 8 | u https://doi.org/10.1007/s00270-022-03176-1 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:150208354 |
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