Search: WFRF:(Caballero Pérez Juan)
> (2018) >
Transcriptional lan...
Transcriptional landscapes of Axolotl (Ambystoma mexicanum)
-
Caballero-Pérez, Juan (author)
-
Espinal-Centeno, Annie (author)
-
Falcon, Francisco (author)
-
show more...
-
García-Ortega, Luis F. (author)
-
Curiel-Quesada, Everardo (author)
-
Cruz-Hernández, Andrés (author)
-
- Bako, Laszlo (author)
- Umeå universitet,Institutionen för fysiologisk botanik,Umeå Plant Science Centre (UPSC)
-
Chen, Xuemei (author)
-
Martínez, Octavio (author)
-
Alberto Arteaga-Vázquez, Mario (author)
-
Herrera-Estrella, Luis (author)
-
Cruz-Ramírez, Alfredo (author)
-
show less...
-
(creator_code:org_t)
- Elsevier, 2018
- 2018
- English.
-
In: Developmental Biology. - : Elsevier. - 0012-1606 .- 1095-564X. ; 433:2, s. 227-239
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- The axolotl (Ambystoma mexicanum) is the vertebrate model system with the highest regeneration capacity. Experimental tools established over the past 100 years have been fundamental to start unraveling the cellular and molecular basis of tissue and limb regeneration. In the absence of a reference genome for the Axolotl, transcriptomic analysis become fundamental to understand the genetic basis of regeneration.Here we present one of the most diverse transcriptomic data sets for Axolotl by profiling coding and non coding RNAs from diverse tissues. We reconstructed a population of 115,906 putative protein coding mRNAs as full ORFs (including isoforms). We also identified 352 conserved miRNAs and 297 novel putative mature miRNAs.Systematic enrichment analysis of gene expression allowed us to identify tissue-specific protein-coding transcripts. We also found putative novel and conserved microRNAs which potentially target mRNAs which are reported as important disease candidates in heart and liver.
Subject headings
- NATURVETENSKAP -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Utvecklingsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Developmental Biology (hsv//eng)
Keyword
- coding and non-coding RNAseq
- axolotl
- regenerative tissues
- microRNAs
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Caballero-Pérez, ...
-
Espinal-Centeno, ...
-
Falcon, Francisc ...
-
García-Ortega, L ...
-
Curiel-Quesada, ...
-
Cruz-Hernández, ...
-
show more...
-
Bako, Laszlo
-
Chen, Xuemei
-
Martínez, Octavi ...
-
Alberto Arteaga- ...
-
Herrera-Estrella ...
-
Cruz-Ramírez, Al ...
-
show less...
- About the subject
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Bioinformatics a ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Developmental Bi ...
- Articles in the publication
-
Developmental Bi ...
- By the university
-
Umeå University