Small bowel capsule endoscopy in obscure gastrointestinal bleeding : A matched cohort comparison of patients with normal vs surgically altered gastric anatomy

Johansson, Gabriele Wurm (author): Lund University,Lunds universitet,Gastroenterologi,Forskargrupper vid Lunds universitet,Gastroenterology,Lund University Research Groups,Skåne University Hospital

Baltes, Peter (author)

Duburque, Clotilde (author)

Koulaouzidis, Anastasios (author): Pomeranian Medical University,Odense University Hospital

(creator_code:org_t)

Elsevier BV, 2022
2022
English.
In: Clinics and Research in Hepatology and Gastroenterology. - : Elsevier BV. - 2210-7401. ; 46:7

Related links:: http://dx.doi.org/10...; show more...; https://lup.lub.lu.s...; https://doi.org/10.1...; show less...

Abstract Subject headings

Background: Little is known about small bowel capsule endoscopy (SBCE) outcomes in patients with surgically altered anatomy. Aims: To assess the feasibility and diagnostic yield of orally ingested SBCE to investigate obscure gastrointestinal bleeding (OGIB) in patients with surgically altered gastric anatomy, compared to native gastric anatomy. Methods: 207 patients with OGIB were selected from an open, multicenter, retrospective cohort (SAGA study) and match-paired according to age, gender and bleeding type (overt/occult) to 207 control patients from a randomized controlled trial (PREPINTEST). Primary outcomes were the diagnostic yield (P1 or P2 findings), completion rate, adverse events rate, and small bowel transit time (SBTT). Results: The diagnostic yield was not statistically different between groups (44.9% in SAGA vs 42.5% in control patients). Inflammatory/ulcerated lesions were significantly more frequent in patients with SAGA (43.0% vs 29.3%). The median SBTT was significantly longer in the SAGA group than in control patients (283 vs 206 minutes), with a significantly lower completion rate (82.6% vs 89.9%); Adverse events were scarce (0.5% vs 0.0%). Conclusion: Patients with surgically altered gastric anatomy should benefit from SBCE investigation for OGIB as much as non-operated patients.

By the author/editor: Dray, Xavier; Rahmi, Gabriel; Riccioni, Maria ...; Vanbiervliet, Ge ...; Johansson, Gabri ...; Leandri, Chloé; show more...; Baltes, Peter; Duburque, Clotil ...; Cholet, Franck; Koulaouzidis, An ...; Quénéhervé, Luci ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Gastroenterology ...

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