A Novel Approach to Hematology Testing at the Point of Care

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A Novel Approach to Hematology Testing at the Point of Care

Bransky, Avishay (author): PixCell Medical Technologies Ltd., Yokneam Ilit, Israel.,PixCell Med Technol Ltd, Israel

Larsson, Anders (author): Uppsala universitet,Klinisk kemi,Uppsala Univ, Sweden

Aardal, Elisabeth (author): Linköpings universitet,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, Klinisk kemi

Ben-Yosef, Yaara (author): PixCell Medical Technologies Ltd., Yokneam Ilit, Israel.,PixCell Med Technol Ltd, Israel

Christenson, Robert H (author): University of Maryland School of Medicine Baltimore, MD.,Univ Maryland, MD 21201 USA

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PixCell Medical Technologies Ltd, Yokneam Ilit, Israel. PixCell Med Technol Ltd, Israel (creator_code:org_t)

2020-12-04
2021
English.
In: The journal of applied laboratory medicine. - : Oxford University Press (OUP). - 2576-9456 .- 2475-7241. ; 6:2, s. 532-542

Related links:: https://europepmc.or...; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; https://urn.kb.se/re...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

BACKGROUND: The need for rapid point-of-care (POC) diagnostics is now becoming more evident due to the increasing need for timely results and improvement in healthcare service. With the recent COVID-19 pandemic outbreak, POC has become critical in managing the spread of disease. Applicable diagnostics should be readily deployable, easy to use, portable, and accurate so that they fit mobile laboratories, pop-up treatment centers, field hospitals, secluded wards within hospitals, or remote regions, and can be operated by staff with minimal training. Complete blood count (CBC), however, has not been available at the POC in a simple-to-use device until recently. The HemoScreen, which was recently cleared by the FDA for POC use, is a miniature, easy-to-use instrument that uses disposable cartridges and may fill this gap.CONTENT: The HemoScreen's analysis method, in contrast to standard laboratory analyzers, is based on machine vision (image-based analysis) and artificial intelligence (AI). We discuss the different methods currently used and compare their results to the vision-based one. The HemoScreen is found to correlate well to laser and impedance-based methods while emphasis is given to mean cell volume (MCV), mean cell hemoglobin (MCH), and platelets (PLT) that demonstrate better correlation when the vision-based method is compared to itself due to the essential differences between the underlying technologies.SUMMARY: The HemoScreen analyzer demonstrates lab equivalent performance, tested at different clinical settings and sample characteristics, and might outperform standard techniques in the presence of certain interferences. This new approach to hematology testing has great potential to improve quality of care in a variety of settings.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)

Keyword

CBC
analyzer
hematology
image analysis
point of care

Publication and Content Type

ref (subject category)
art (subject category)

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By the author/editor: Bransky, Avishay; Larsson, Anders; Aardal, Elisabet ...; Ben-Yosef, Yaara; Christenson, Rob ...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Clinical Laborat ...

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