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Gastroesophageal reflux and snoring are related to asthma and respiratory symptoms : Results from a Nordic longitudinal population survey.

Mir Fakhraei, Rima (författare)
Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
Lindberg, Eva (författare)
Uppsala universitet,Lung- allergi- och sömnforskning,Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
Benediktsdóttir, Bryndís (författare)
Faculty of Medicine, University of Iceland, Reykjavik, Iceland
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Svanes, Cecilie (författare)
Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway; Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway
Johannessen, Ane (författare)
Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
Holm, Mathias, 1969 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
Modig, Lars (författare)
Umeå universitet,Avdelningen för hållbar hälsa
Franklin, Karl A. (författare)
Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap
Malinovschi, Andrei, 1978- (författare)
Uppsala universitet,Klinisk fysiologi,Lung- allergi- och sömnforskning,Department of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden
Gislason, Thorarinn (författare)
Faculty of Medicine, University of Iceland, Reykjavik, Iceland; Department of Sleep, Landspitali, University Hospital, Reykjavik, Iceland
Jögi, Rain (författare)
Uppsala universitet,Lung- allergi- och sömnforskning,The Lung Clinic, Tartu University Hospital, Tartu, Estonia
Cramer, Christine (författare)
Department of Public Health, Aarhus University, Aarhus, Denmark; Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark
Janson, Christer (författare)
Uppsala universitet,Lung- allergi- och sömnforskning,Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
Emilsson, Össur Ingi (författare)
Uppsala universitet,Lung- allergi- och sömnforskning,Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden; Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Emilsson, Ossuringi (författare)
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 (creator_code:org_t)
Elsevier, 2024
2024
Engelska.
Ingår i: Respiratory Medicine. - : Elsevier. - 0954-6111 .- 1532-3064. ; 221
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • AIM: To study if individuals with nocturnal gastroesophageal reflux (nGER) and habitual snoring are more likely to develop asthma and respiratory symptoms (i.e. wheeze, cough, chest tightness, breathlessness) than those without these conditions, and if these associations are additive.METHODS: We used data from the population-based prospective questionnaire study Respiratory Health in Northern Europe (RHINE) (11,024 participants), with data from 1999 and 2011. Participants with heartburn or belching after going to bed, at least 1 night/week, were considered to have nGER. Participants reporting loud snoring at least 3 nights/week were considered to have habitual snoring. Participants were grouped into four groups by their nGER and snoring status: "never"; "former"; "incident"; "persistent". Incident respiratory symptoms were analyzed among participants without respective symptom at baseline.RESULTS: Snoring and nGER were independently associated with incident asthma and respiratory symptoms. The risk of incident wheeze was increased in subjects with incident or persistent snoring (adjusted odds ratio (95 % CI): 1.44 (1.21-1.72)), nGER (2.18 (1.60-2.98)) and in those with both snoring and nGER (2.59 (1.83-3.65)). The risk of developing asthma was increased in subjects with incident or persistent snoring (1.44 (1.15-1.82)), nGER (1.99 (1.35-2.93)) and in those with both snoring and nGER (1.72 (1.06-2.77)). No significant interaction was found between snoring and nGER. A similar pattern was found for the incidence of all other respiratory symptoms studied, with the highest risk among those with both incident or persistent nGER and snoring.CONCLUSION: The risk of developing asthma and respiratory symptoms is increased among subjects with nGER and habitual snoring. These associations are independent of each other and confounding factors. Snoring and nGER together are additive on respiratory symptoms.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)

Nyckelord

Asthma
Epidemiology
Habitual snoring
Nocturnal gastroesophageal reflux
Respiratory symptom
Lungmedicin
Lung Medicine
Fysiologi
Physiology
Nocturnal gastroesophageal reflux
Asthma
Habitual snoring
Respiratory symptom
Epidemiology

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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