Sökning: WFRF:(Fazzari Melissa J) > Tidskriftsartikel > Genome of the marsu...
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000 | 05421naa a2201189 4500 | |
001 | oai:DiVA.org:uu-15798 | |
003 | SwePub | |
008 | 080306s2007 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-157982 URI |
024 | 7 | a https://doi.org/10.1038/nature058052 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Mikkelsen, Tarjei S4 aut |
245 | 1 0 | a Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences |
264 | 1 | b Springer Science and Business Media LLC,c 2007 |
338 | a print2 rdacarrier | |
520 | a We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis domestica). As the first metatherian ('marsupial') species to be sequenced, the opossum provides a unique perspective on the organization and evolution of mammalian genomes. Distinctive features of the opossum chromosomes provide support for recent theories about genome evolution and function, including a strong influence of biased gene conversion on nucleotide sequence composition, and a relationship between chromosomal characteristics and X chromosome inactivation. Comparison of opossum and eutherian genomes also reveals a sharp difference in evolutionary innovation between protein-coding and non-coding functional elements. True innovation in protein-coding genes seems to be relatively rare, with lineage-specific differences being largely due to diversification and rapid turnover in gene families involved in environmental interactions. In contrast, about 20% of eutherian conserved non-coding elements (CNEs) are recent inventions that postdate the divergence of Eutheria and Metatheria. A substantial proportion of these eutherian-specific CNEs arose from sequence inserted by transposable elements, pointing to transposons as a major creative force in the evolution of mammalian gene regulation. | |
653 | a Animals | |
653 | a Base Composition | |
653 | a Conserved Sequence/genetics | |
653 | a DNA Transposable Elements/genetics | |
653 | a Evolution; Molecular | |
653 | a Genome/*genetics | |
653 | a Genomics | |
653 | a Humans | |
653 | a Opossums/*genetics | |
653 | a Polymorphism; Single Nucleotide/genetics | |
653 | a Protein Biosynthesis | |
653 | a Synteny/genetics | |
653 | a X Chromosome Inactivation/genetics | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Wakefield, Matthew J4 aut |
700 | 1 | a Aken, Bronwen4 aut |
700 | 1 | a Amemiya, Chris T4 aut |
700 | 1 | a Chang, Jean L4 aut |
700 | 1 | a Duke, Shannon4 aut |
700 | 1 | a Garber, Manuel4 aut |
700 | 1 | a Gentles, Andrew J4 aut |
700 | 1 | a Goodstadt, Leo4 aut |
700 | 1 | a Heger, Andreas4 aut |
700 | 1 | a Jurka, Jerzy4 aut |
700 | 1 | a Kamal, Michael4 aut |
700 | 1 | a Mauceli, Evan4 aut |
700 | 1 | a Searle, Stephen M J4 aut |
700 | 1 | a Sharpe, Ted4 aut |
700 | 1 | a Baker, Michelle L4 aut |
700 | 1 | a Batzer, Mark A4 aut |
700 | 1 | a Benos, Panayiotis V4 aut |
700 | 1 | a Belov, Katherine4 aut |
700 | 1 | a Clamp, Michele4 aut |
700 | 1 | a Cook, April4 aut |
700 | 1 | a Cuff, James4 aut |
700 | 1 | a Das, Radhika4 aut |
700 | 1 | a Davidow, Lance4 aut |
700 | 1 | a Deakin, Janine E4 aut |
700 | 1 | a Fazzari, Melissa J4 aut |
700 | 1 | a Glass, Jacob L4 aut |
700 | 1 | a Grabherr, Manfred4 aut |
700 | 1 | a Greally, John M4 aut |
700 | 1 | a Gu, Wanjun4 aut |
700 | 1 | a Hore, Timothy A4 aut |
700 | 1 | a Huttley, Gavin A4 aut |
700 | 1 | a Kleber, Michael4 aut |
700 | 1 | a Jirtle, Randy L4 aut |
700 | 1 | a Koina, Edda4 aut |
700 | 1 | a Lee, Jeannie T4 aut |
700 | 1 | a Mahony, Shaun4 aut |
700 | 1 | a Marra, Marco A4 aut |
700 | 1 | a Miller, Robert D4 aut |
700 | 1 | a Nicholls, Robert D4 aut |
700 | 1 | a Oda, Mayumi4 aut |
700 | 1 | a Papenfuss, Anthony T4 aut |
700 | 1 | a Parra, Zuly E4 aut |
700 | 1 | a Pollock, David D4 aut |
700 | 1 | a Ray, David A4 aut |
700 | 1 | a Schein, Jacqueline E4 aut |
700 | 1 | a Speed, Terence P4 aut |
700 | 1 | a Thompson, Katherine4 aut |
700 | 1 | a VandeBerg, John L4 aut |
700 | 1 | a Wade, Claire M4 aut |
700 | 1 | a Walker, Jerilyn A4 aut |
700 | 1 | a Waters, Paul D4 aut |
700 | 1 | a Webber, Caleb4 aut |
700 | 1 | a Weidman, Jennifer R4 aut |
700 | 1 | a Xie, Xiaohui4 aut |
700 | 1 | a Zody, Michael C4 aut |
700 | 1 | a Graves, Jennifer A Marshall4 aut |
700 | 1 | a Ponting, Chris P4 aut |
700 | 1 | a Breen, Matthew4 aut |
700 | 1 | a Samollow, Paul B4 aut |
700 | 1 | a Lander, Eric S4 aut |
700 | 1 | a Lindblad-Toh, Kerstinu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi4 aut0 (Swepub:uu)kerli865 |
710 | 2 | a Uppsala universitetb Institutionen för medicinsk biokemi och mikrobiologi4 org |
773 | 0 | t Natured : Springer Science and Business Media LLCg 447:7141, s. 167-177q 447:7141<167-177x 0028-0836x 1476-4687 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=17495919&dopt=Citation |
856 | 4 | u https://www.nature.com/articles/nature05805.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-15798 |
856 | 4 8 | u https://doi.org/10.1038/nature05805 |
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