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Perilous paradigm o...
Perilous paradigm of graphene oxide and its derivatives in biomedical applications : Insight to immunocompatibility
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- Ayreen, Zobia (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Khatoon, Uzma (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Kirti, Apoorv (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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visa fler...
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- Sinha, Adrija (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Gupta, Abha (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Lenka, Sudakshya S. (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Yadav, Anu (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Mohanty, Rupali (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Naser, Shaikh Sheeran (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Mishra, Richa (författare)
- Parul Univ, Vadodara 391760, Gujarat, India.
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- Chouhan, Raghuraj Singh (författare)
- Jozef Stefan Inst, Dept Environm Sci, Jamova Cesta 39, Ljubljana 1000, Slovenia.
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- Samal, Shailesh Kumar (författare)
- Karolinska Inst, Dept Environm Med, Stockholm, Sweden.
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- Kaushik, Nagendra Kumar (författare)
- Kwangwoon Univ, Plasma Biosci Res Ctr, Dept Elect & Biol Phys, Seoul 01897, South Korea.
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- Singh, Deobrat (författare)
- Uppsala universitet,Materialteori
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- Suar, Mrutyunjay (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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- Verma, Suresh K. (författare)
- KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India.
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KIIT Univ, KIIT Sch Biotechnol, Bhubaneswar 751024, Odisha, India Parul Univ, Vadodara 391760, Gujarat, India. (creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: Biomedicine and Pharmacotherapy. - : Elsevier. - 0753-3322 .- 1950-6007. ; 176
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- With advancements in nanotechnology and innovative materials, Graphene Oxide nanoparticles (GONP) have attracted lots of attention among the diverse types of nanomaterials owing to their distinctive physicochemical characteristics. However, the usage at scientific and industrial level has also raised concern to their toxicological interaction with biological system. Understanding these interactions is crucial for developing guidelines and recommendations for applications of GONP in various sectors, like biomedicine and environmental technologies. This review offers crucial insights and an in-depth analysis to the biological processes associated with GONP immunotoxicity with multiple cell lines including human whole blood cultures, dendritic cells, macrophages, and multiple cancer cell lines. The complicated interactions between graphene oxide nanoparticles and the immune system, are highlighted in this work, which reveals a range of immunotoxic consequences like inflammation, immunosuppression, immunostimulation, hypersensitivity, autoimmunity, and cellular malfunction. Moreover, the immunotoxic effects are also highlighted with respect to in vivo models like mice and zebrafish, insighting GO Nanoparticles' cytotoxicity. The study provides invaluable review for researchers, policymakers, and industrialist to understand and exploit the beneficial applications of GONP with a controlled measure to human health and the environment.
Ämnesord
- NATURVETENSKAP -- Kemi -- Materialkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Materials Chemistry (hsv//eng)
Nyckelord
- Graphene Oxide
- Nanoparticles
- Immune system
- Cell lines
- Human model
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Ayreen, Zobia
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Khatoon, Uzma
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Kirti, Apoorv
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Sinha, Adrija
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Gupta, Abha
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Lenka, Sudakshya ...
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Yadav, Anu
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Mohanty, Rupali
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Naser, Shaikh Sh ...
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Mishra, Richa
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Chouhan, Raghura ...
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Samal, Shailesh ...
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Kaushik, Nagendr ...
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Singh, Deobrat
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Suar, Mrutyunjay
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Verma, Suresh K.
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- Om ämnet
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- NATURVETENSKAP
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NATURVETENSKAP
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och Kemi
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och Materialkemi
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Biomedicine and ...
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Uppsala universitet