Injectable bone cements for vertebroplasty studied in sheep vertebrae with electron microscopy

Vertebral compression fractures were simulated by making a hole into sheep vertebrae and by injecting a stabilizing material. The injectable bio-ceramic Xeraspine™ was evaluated together with a commercially available PMMA (Vertebroplastic™) as the reference material. The Vertebrae were harvested after 7 days and prepared for microscopy. The samples were deposited with gold on the surface and thereafter subjected to SEM and EDX analysis. It was found that the Xeraspine-bone interface was composed of a mixture of elements. The Vertebroplastic implant was embedded in a carbon containing tissue, likely a soft tissue capsule. The Xeraspine sample was subjected to high resolution analysis in the TEM combined with EDX measurements. The TEM sample was prepared with a novel technique for preparation of the tissue-material interface (FIB). In the TEM analysis it was found that the interface region consists of ZrO2 together with a mixture possibly consisting of katoite and apatite formed during setting and/or originating from the boneapatite.

Uhlin, T (författare)
Höglund, U (författare)
Thomsen, Peter,1953Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials(Swepub:gu)xthope (författare)
Hermansson, L (författare)
Engqvist, H (författare)
Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap (creator_code:org_t)

Av författaren/redakt...: Jarmar, Tobias; Uhlin, T; Höglund, U; Thomsen, Peter, ...; Hermansson, L; Engqvist, H

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Medicinsk biotek ...; och Biomaterialveten ...

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