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Core Outcome Sets (COS) related to pregnancy and childbirth : a systematic review

Osterberg, Marie (author)
Swedish Agcy Hlth Technol Assessment & Assessment, Stockholm, Sweden.
Hellberg, Christel (author)
Swedish Agcy Hlth Technol Assessment & Assessment, Stockholm, Sweden.
Jonsson, Ann Kristine (author)
Swedish Agcy Hlth Technol Assessment & Assessment, Stockholm, Sweden.
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Fundell, Sara (author)
Swedish Agcy Hlth Technol Assessment & Assessment, Stockholm, Sweden.
Tronnberg, Frida (author)
Patient Representat, Linköping, Sweden.
Skalkidou, Alkistis, 1977- (author)
Uppsala universitet,Obstetrisk och reproduktiv hälsoforskning
Jonsson, Maria, 1966- (author)
Uppsala universitet,Klinisk obstetrik
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Swedish Agcy Hlth Technol Assessment & Assessment, Stockholm, Sweden Patient Representat, Linköping, Sweden. (creator_code:org_t)
2021-10-09
2021
English.
In: BMC Pregnancy and Childbirth. - : BioMed Central (BMC). - 1471-2393 .- 1471-2393. ; 21:1
  • Research review (peer-reviewed)
Abstract Subject headings
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  • BackgroundSystematic reviews often conclude low confidence in the results due to heterogeneity in the reported outcomes. A Core Outcome Set (COS) is an agreed standardised collection of outcomes for a specific area of health. The outcomes included in a COS are to be measured and summarized in clinical trials as well as systematic reviews to counteract this heterogeneity.AimThe aim is to identify, compile and assess final and ongoing studies that are prioritizing outcomes in the area of pregnancy and childbirth.MethodsAll studies which prioritized outcomes related to pregnancy and childbirth using consensus method, including Delphi surveys or consensus meetings were included. Searches were conducted in Ovid MEDLINE, EMBASE, PsycINFO, Academic Search Elite, CINAHL, SocINDEX and COMET databases up to June 2021. For all studies fulfilling the inclusion criteria, information regarding outcomes as well as population, method, and setting was extracted. In addition, reporting in the finalized studies was assessed using a modified version of the Core Outcome Set-STAndards for Reporting.ResultsIn total, 27 finalized studies and 42 ongoing studies were assessed as relevant and were included. In the finalized studies, the number of outcomes included in the COS ranged from 6 to 51 with a median of 13 outcomes. The majority of the identified COS, both finalized as well as ongoing, were relating to physical complications during pregnancy.ConclusionThere is a growing number of Core Outcome Set studies related to pregnancy and childbirth. Although several of the finalized studies follow the proposed reporting, there are still some items that are not always clearly reported. Additionally, several of the identified COS contained a large number (n > 20) outcomes, something that possibly could hinder implementation. Therefore, there is a need to consider the number of outcomes which may be included in a COS to render it optimal for future research.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)

Keyword

Core outcome set
Consensus methods
Maternal health
Obstetric care
Pregnancy
Prenatal

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