High throughput separation of bacteria from blood for sepsis diagnostics using extended elasto-inertial microfluidics

Mårtensson, Gustaf (author): KTH,Skolan för kemi, bioteknologi och hälsa (CBH)

Russom, Aman, Assoc.Prof. (author): KTH,Science for Life Laboratory, SciLifeLab,Nanobioteknologi

(creator_code:org_t)

Chemical and Biological Microsystems Society, 2019
2019
English.
In: 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019. - : Chemical and Biological Microsystems Society. ; , s. 590-591

Abstract Subject headings

Separation of bacteria from blood for sepsis diagnostics has received substantial interest due to lack of high throughput alternatives. Here, we introduce extended elasto-inertial microfluidics based high throughput (1 mL/min) separation of bacteria from whole blood. We demonstrate separation of E.coli from 1 mL of whole blood in 40 min using a single spiral chip with 90% separation efficiency. This opens up opportunities by aiding for downstream analysis, by reducing the time of sample preparation for sepsis diagnosis.

By the author/editor: Iyengar, Sharath ...; Kumar, Tharagan; Mårtensson, Gust ...; Russom, Aman, As ...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Chemical Science ...; and Analytical Chemi ...

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