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WFRF:(Kaptan Damla)
 

Sökning: WFRF:(Kaptan Damla) > Population Genomic ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005784naa a2200637 4500
001oai:DiVA.org:uu-530595
003SwePub
008240613s2024 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5305952 URI
0247 a https://doi.org/10.1093/gbe/evae0902 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Atag, Gözdeu Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
2451 0a Population Genomic History of the Endangered Anatolian and Cyprian Mouflons in Relation to Worldwide Wild, Feral, and Domestic Sheep Lineages
264 1b Oxford University Press,c 2024
338 a electronic2 rdacarrier
520 a Once widespread in their homelands, the Anatolian mouflon (Ovis gmelini anatolica) and the Cyprian mouflon (Ovis gmelini ophion) were driven to near extinction during the 20th century and are currently listed as endangered populations by the International Union for Conservation of Nature. While the exact origins of these lineages remain unclear, they have been suggested to be close relatives of domestic sheep or remnants of proto-domestic sheep. Here, we study whole genome sequences of n = 5 Anatolian mouflons and n = 10 Cyprian mouflons in terms of population history and diversity, comparing them with eight other extant sheep lineages. We find reciprocal genetic affinity between Anatolian and Cyprian mouflons and domestic sheep, higher than all other studied wild sheep genomes, including the Iranian mouflon (O. gmelini). Studying diversity indices, we detect a considerable load of short runs of homozygosity blocks (<2 Mb) in both Anatolian and Cyprian mouflons, reflecting small effective population size (N-e). Meanwhile, N-e and mutation load estimates are lower in Cyprian compared with Anatolian mouflons, suggesting the purging of recessive deleterious variants in Cyprian sheep under a small long-term N-e, possibly attributable to founder effects, island isolation, introgression from domestic lineages, or differences in their bottleneck dynamics. Expanding our analyses to worldwide wild and feral Ovis genomes, we observe varying viability metrics among different lineages and a limited consistency between viability metrics and International Union for Conservation of Nature conservation status. Factors such as recent inbreeding, introgression, and unique population dynamics may have contributed to the observed disparities.
650 7a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng
653 a sheep
653 a genomics
653 a conservation
653 a domestication
7001 a Kaptan, Damlau Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7001 a Yüncü, Erenu Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7001 a Vural, Kivilcim Basaku Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7001 a Mereu, Paolou Univ Sassari, Dept Biochem Sci, Sassari, Italy.4 aut
7001 a Pirastru, Monicau Univ Sassari, Dept Biochem Sci, Sassari, Italy.4 aut
7001 a Barbato, Mariou Univ Messina, Dept Vet Sci, Messina, Italy.4 aut
7001 a Leoni, Giovanni Giuseppeu Univ Sassari, Dept Biochem Sci, Sassari, Italy.4 aut
7001 a Güler, Merve Nuru Middle East Tech Univ, Grad Sch Informat, Dept Hlth Informat, Ankara, Turkiye.4 aut
7001 a Er, Tugceu Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7001 a Eker, Elifnazu Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7001 a Yazici, Tunca Denizu Ludwig Maximillian Univ Munich, Grad Sch Evolut Ecol & Systemat, Munich, Germany.4 aut
7001 a Kilic, Muhammed Siddiku Middle East Tech Univ, Grad Sch Informat, Dept Hlth Informat, Ankara, Turkiye.4 aut
7001 a Altinisik, Nefize Ezgiu Hacettepe Univ, Dept Anthropol, Ankara, Turkiye.4 aut
7001 a Celik, Ecem Ayseu Middle East Tech Univ, Dept Settlement Archeol, Ankara, Turkiye.4 aut
7001 a Morell Miranda, Pedrou Uppsala universitet,Människans evolution4 aut0 (Swepub:uu)pedmo131
7001 a Dehasque, Marianneu Uppsala universitet,Människans evolution4 aut0 (Swepub:uu)marde994
7001 a Floridia, Vivianau Department of Veterinary Sciences, University of Messina, Messina, Italy4 aut
7001 a Götherström, Andersu Stockholm Univ, Dept Archaeol & Class Studies, Stockholm, Sweden.;Stockholm Univ, Ctr Palaeogenet, Stockholm, Sweden.4 aut
7001 a Bilgin, Cemal Canu Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7001 a Togan, Inciu Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7001 a Günther, Torsten,c Dru Uppsala universitet,Människans evolution4 aut0 (Swepub:uu)torgu835
7001 a Özer, Füsunu Hacettepe Univ, Dept Anthropol, Ankara, Turkiye.4 aut
7001 a Hadjisterkotis, Eleftheriosu Minist Agr Rural Dev & Environm, Agr Res Inst, Nicosia, Cyprus.4 aut
7001 a Somel, Mehmetu Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.4 aut
7102 a Middle East Tech Univ, Dept Biol Sci, Ankara, Turkiye.b Univ Sassari, Dept Biochem Sci, Sassari, Italy.4 org
7730 t Genome Biology and Evolutiond : Oxford University Pressg 16:5q 16:5x 1759-6653
8564 u https://doi.org/10.1093/gbe/evae090y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1869639/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-530595
8564 8u https://doi.org/10.1093/gbe/evae090

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