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Sökning: WFRF:(KuntzeSoderqvist A) > (2019) > Posterior communica...

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FältnamnIndikatorerMetadata
00003881naa a2200445 4500
001oai:prod.swepub.kib.ki.se:141262447
003SwePub
008240701s2019 | |||||||||||000 ||eng|
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1412624472 URI
0247 a https://doi.org/10.1177/15910199198312152 DOI
040 a (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Yeo, LLLu Karolinska Institutet4 aut
2451 0a Posterior communicating and anterior communicating arteries on pre-thrombectomy computed tomography scans are associated with good outcomes irrespective of leptomeningeal collateral status
264 c 2019-02-25
264 1b SAGE Publications,c 2019
520 a Collateral blood flow is known to be an important factor that sustains the penumbra during acute stroke. We looked at both the leptomeningeal collateral circulation and the presence of anterior and posterior communicating arteries to determine the factors associated with good outcomes and mortality. Methods We included all patients with acute ischaemic stroke in the anterior circulation, who underwent thrombectomy with the same thrombectomy device from 2013 to 2016. We assessed the leptomeningeal circulation by the Tan, Miteff and Maas validated scoring systems on pre-treatment computed tomographic angiography scans and looked at collateral flow through anterior and posterior communicating arteries. The results were good functional outcomes at 3 months (modified Rankin scale 0–2) and mortality. Results A total of 147 consecutive acute stroke patients treated with the Embotrap device were included with a median National Institutes of Health stroke scale of 15 (range 2–26). On multivariate analysis only younger age (odds ratio (OR) 0.96/year, 95% confidence interval (CI) 0.94–0.99, P = 0.026), lower National Institutes of Health stroke scale score (OR 0.87/point, 95% CI 0.80–0.93, P < 0.001), number of attempts (OR 0.80/attempt, 95% CI 0.65–0.99, P = 0.043) and the presence of a patent anterior communicating artery (OR 14.03, 95% CI 1.42–139.07, P = 0.024) were associated with good functional outcomes. The number of attempts (OR 1.66/attempt, 95% CI 1.21–2.29, P = 0.002) was significantly associated with mortality and the presence of a patent posterior communicating artery (OR 0.098, 95% CI 0.016–0.59, P = 0.011) was inversely associated with mortality. Conclusions Our study shows that the presence of anterior and posterior communicating arteries is significantly associated with good functional outcomes and reduced mortality, respectively, independent of the leptomeningeal circulation status.
7001 a Andersson, Tu Karolinska Institutet4 aut
7001 a Holmberg, A4 aut
7001 a Mpotsaris, A4 aut
7001 a Soderman, Mu Karolinska Institutet4 aut
7001 a Holmin, Su Karolinska Institutet4 aut
7001 a Bhogal, P4 aut
7001 a Yang, CL4 aut
7001 a Gopinathan, A4 aut
7001 a Tan, BYQ4 aut
7001 a Gontu, V4 aut
7001 a Kolloch, J4 aut
7001 a KuntzeSoderqvist, Au Karolinska Institutet4 aut
7001 a Brouwer, PA4 aut
7001 a Cornelissen, S4 aut
7102 a Karolinska Institutet4 org
7730 t Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciencesd : SAGE Publicationsg 25:4, s. 364-370q 25:4<364-370x 2385-2011
7730 t Interventional Neuroradiologyd : SAGE Publicationsg 25:4, s. 364-370q 25:4<364-370x 1591-0199
8564 u https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607609
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:141262447
8564 8u https://doi.org/10.1177/1591019919831215

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