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WFRF:(Lou Wenhui)
 

Sökning: WFRF:(Lou Wenhui) > (2021) > Development, valida...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006130naa a2201057 4500
001oai:DiVA.org:umu-193275
003SwePub
008220324s2021 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:146377687
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1932752 URI
0247 a https://doi.org/10.1002/jhbp.9622 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1463776872 URI
040 a (SwePub)umud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Kim, Hyeong Seok4 aut
2451 0a Development, validation, and comparison of a nomogram based on radiologic findings for predicting malignancy in intraductal papillary mucinous neoplasms of the pancreas :b An international multicenter study
264 c 2021
264 1b Wiley-Blackwell,c 2021
338 a print2 rdacarrier
520 a BACKGROUND: Although we previously proposed a nomogram to predict malignancy in intraductal papillary mucinous neoplasms (IPMN) and validated it in an external cohort, its application is challenging without data on tumor markers. Moreover, existing nomograms have not been compared. This study aimed to develop a nomogram based on radiologic findings and to compare its performance with previously proposed American and Korean/Japanese nomograms.METHODS: We recruited 3708 patients who underwent surgical resection at 31 tertiary institutions in eight countries, and patients with main pancreatic duct >10 mm were excluded. To construct the nomogram, 2606 patients were randomly allocated 1:1 into training and internal validation sets, and area under the receiver operating characteristics curve (AUC) was calculated using 10-fold cross validation by exhaustive search. This nomogram was then validated and compared to the American and Korean/Japanese nomograms using 1102 patients.RESULTS: Among the 2606 patients, 90 had main-duct type, 900 had branch-duct type, and 1616 had mixed-type IPMN. Pathologic results revealed 1628 low-grade dysplasia, 476 high-grade dysplasia, and 502 invasive carcinoma. Location, cyst size, duct dilatation, and mural nodule were selected to construct the nomogram. AUC of this nomogram was higher than the American nomogram (0.691 vs 0.664, P = .014) and comparable with the Korean/Japanese nomogram (0.659 vs 0.653, P = .255).CONCLUSIONS: A novel nomogram based on radiologic findings of IPMN is competitive for predicting risk of malignancy. This nomogram would be clinically helpful in circumstances where tumor markers are not available. The nomogram is freely available at http://statgen.snu.ac.kr/software/nomogramIPMN.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a cancer
653 a intraductal papillary mucinous neoplasms of the pancreas
653 a malignancy prediction
653 a nomogram
653 a radiology
7001 a Song, Wookyeong4 aut
7001 a Choo, Wonho4 aut
7001 a Lee, Sungyoung4 aut
7001 a Han, Youngmin4 aut
7001 a Bassi, Claudio4 aut
7001 a Salvia, Roberto4 aut
7001 a Marchegiani, Giovanni4 aut
7001 a Wolfgang, Christopher L.4 aut
7001 a He, Jin4 aut
7001 a Blair, Alex B.4 aut
7001 a Kluger, Michael D.4 aut
7001 a Su, Gloria H.4 aut
7001 a Kim, Song Cheol4 aut
7001 a Song, Ki-Byung4 aut
7001 a Yamamoto, Masakazu4 aut
7001 a Hatori, Takashi4 aut
7001 a Yang, Ching-Yao4 aut
7001 a Yamaue, Hiroki4 aut
7001 a Hirono, Seiko4 aut
7001 a Satoi, Sohei4 aut
7001 a Fujii, Tsutomu4 aut
7001 a Hirano, Satoshi4 aut
7001 a Lou, Wenhui4 aut
7001 a Hashimoto, Yasushi4 aut
7001 a Shimizu, Yasuhiro4 aut
7001 a Del Chiaro, Marco4 aut
7001 a Valente, Robertou Pancreatic Surgery Unit, Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute at Center for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden; Digestive and Liver Disease Unit, Sapienza University of Rome, Rome, Italy4 aut0 (Swepub:umu)rova0033
7001 a Lohr, Matthiasu Karolinska Institutet4 aut
7001 a Choi, Dong Wook4 aut
7001 a Choi, Seong Ho4 aut
7001 a Heo, Jin Seok4 aut
7001 a Motoi, Fuyuhiko4 aut
7001 a Matsumoto, Ippei4 aut
7001 a Lee, Woo Jung4 aut
7001 a Kang, Chang Moo4 aut
7001 a Shyr, Yi-Ming4 aut
7001 a Wang, Shin-E4 aut
7001 a Han, Ho-Seong4 aut
7001 a Yoon, Yoo-Seok4 aut
7001 a Besselink, Marc G.4 aut
7001 a van Huijgevoort, Nadine C. M.4 aut
7001 a Sho, Masayuki4 aut
7001 a Nagano, Hiroaki4 aut
7001 a Kim, Sang Geol4 aut
7001 a Honda, Goro4 aut
7001 a Yang, Yinmo4 aut
7001 a Yu, Hee Chul4 aut
7001 a Yang, Jae Do4 aut
7001 a Chung, Jun Chul4 aut
7001 a Nagakawa, Yuichi4 aut
7001 a Seo, Hyung Il4 aut
7001 a Lee, Seungyeoun4 aut
7001 a Kim, Hongbeom4 aut
7001 a Kwon, Wooil4 aut
7001 a Park, Taesung4 aut
7001 a Jang, Jin-Young4 aut
7102 a Karolinska Institutetb Pancreatic Surgery Unit, Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute at Center for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden; Digestive and Liver Disease Unit, Sapienza University of Rome, Rome, Italy4 org
7730 t Journal of hepato-biliary-pancreatic sciencesd : Wiley-Blackwellx 1868-6974x 1868-6982
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-193275
8564 8u https://doi.org/10.1002/jhbp.962
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:146377687

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