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FältnamnIndikatorerMetadata
00005659naa a2200637 4500
001oai:DiVA.org:liu-79986
003SwePub
008120817s2012 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:893d8989-365e-4f2d-a6de-ed6d534ab83c
009oai:prod.swepub.kib.ki.se:124954446
009oai:DiVA.org:umu-57864
009oai:DiVA.org:uu-179577
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-799862 URI
0247 a https://doi.org/10.3109/0284186X.2012.6810642 DOI
0247 a https://lup.lub.lu.se/record/29793172 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1249544462 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-578642 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1795772 URI
040 a (SwePub)liud (SwePub)lud (SwePub)kid (SwePub)umud (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Holgersson, Georgu Uppsala universitet,Enheten för onkologi,Centrum för klinisk forskning, Gävleborg,Uppsala University Hospital, Sweden4 aut0 (Swepub:uu)geoho179
2451 0a Swedish Lung Cancer Radiation Study Group: Predictive value of age at diagnosis for radiotherapy response in patients with non-small cell lung cancer
264 1a London :b Informa Healthcare,c 2012
338 a print2 rdacarrier
500 a Funding Agencies|Stiftelsen Gavle Cancerfond||
520 a Introduction. The aim of the present study was to investigate the impact of age at diagnosis on prognosis in patients treated with curatively intended radiotherapy for NSCLC. Material and methods. This is a joint effort among all the Swedish Oncology Departments that includes all identified patients with a diagnosed non-small cell lung cancer that have been subjected to curatively intended irradiation (andgt;= 50 Gy) treated during 1990 to 2000. Included patients had a histopathological/cytological diagnosis date as well as a death date or a last follow-up date. The following variables were studied in relation to overall and disease-specific survival: age, gender, histopathology, time period, smoking status, stage and treatment. Results. The median overall survival of all 1146 included patients was 14.7 months, while the five-year overall survival rate was 9.5%. Younger patients (andlt;55 years), presented with a more advanced clinical stage but had yet a significantly better overall survival compared with patients in the age groups 55-64 years (p = 0.035) and 65-74 years (p = 0.0097) in a multivariate Cox regression analysis. The overall survival of patients aged andgt;= 75 years was comparable to those aged andlt;55 years. Conclusion. In this large retrospective study we describe that patients younger than 55 years treated with curatively intended radiotherapy for NSCLC have a better overall survival than patients aged 55-64 and 65-74 years and that younger patients seem to benefit more from the addition of surgery and/or chemotherapy to radiotherapy. Due to the exploratory nature of the study, these results should be confirmed in future prospective trials.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a TECHNOLOGY
653 a TEKNIKVETENSKAP
7001 a Hoye, Evenu Gävle Hospital, Sweden4 aut
7001 a Bergqvist, Michaelu Uppsala universitet,Enheten för onkologi,Uppsala University Hospital, Sweden4 aut0 (Swepub:uu)michberg
7001 a Ekman, Simonu Uppsala universitet,Enheten för onkologi,Uppsala University Hospital, Sweden4 aut0 (Swepub:uu)simoekma
7001 a Nyman, Janu Sahlgrenska University Hospital, Göteborg, Sweden4 aut
7001 a Helsing, Martinu Örebro University Hospital, Sweden4 aut
7001 a Friesland, Signeu Karolinska Institutet,Karolinska University Hospital, Stockholm, Sweden4 aut
7001 a Holgersson, Margaretau Uppsala universitet,Enheten för onkologi,Uppsala University Hospital, Sweden4 aut
7001 a Ekberg, Larsu Skåne University Hospital, Malmö, Sweden4 aut
7001 a Blystad, Thomasu Östergötlands Läns Landsting,Lungmedicinska kliniken US4 aut
7001 a Ewers, Sven-Börjeu Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Hospital, Sweden4 aut0 (Swepub:lu)onk-sbe
7001 a Mörth, Charlotteu Mälar Hospital, Eskilstuna, Sweden4 aut
7001 a Löden, Brittau Central Hospital, Karlstad, Sweden4 aut
7001 a Henriksson, Rogeru Umeå universitet,Onkologi,Umeå University Hospital, Sweden4 aut0 (Swepub:umu)rohe0003
7001 a Bergström, Stefanu Gävle Hospital, Sweden4 aut
7102 a Uppsala universitetb Enheten för onkologi4 org
7730 t Acta Oncologicad London : Informa Healthcareg 51:6, s. 759-767q 51:6<759-767x 0284-186Xx 1651-226X
8564 u http://dx.doi.org/10.3109/0284186X.2012.681064y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-79986
8564 8u https://doi.org/10.3109/0284186X.2012.681064
8564 8u https://lup.lub.lu.se/record/2979317
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:124954446
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-57864
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179577

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