Modulatory effect of raloxifene and estrogen on the metabolic action of growth hormone in hypopituitary women.

• The metabolic action of GH is attenuated by estrogens administered via the oral route. Selective estrogen receptor modulators lower IGF-I to a lesser degree than 17beta-estradiol in GH-deficient women, and their effect on fat and protein metabolism is unknown.

Keyword

Adult

Calorimetry

Indirect

Cross-Over Studies

Drug Therapy

Combination

Estradiol

therapeutic use

Estrogen Replacement Therapy

Female

Human Growth Hormone

blood

Humans

Hypopituitarism

drug therapy

Insulin-Like Growth Factor Binding Protein 3

metabolism

Insulin-Like Growth Factor I

metabolism

Leucine

metabolism

Middle Aged

Raloxifene

therapeutic use

Selective Estrogen Receptor Modulators

therapeutic use

Publication and Content Type

ref (subject category)

art (subject category)