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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004188naa a2200553 4500
001oai:DiVA.org:umu-110944
003SwePub
008151029s2005 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-80617
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1109442 URI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-806172 URI
024a https://doi.org/10.1136/ard.2004.0297282 DOI
040 a (SwePub)umud (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Wanders, A.4 aut
2451 0a Association between radiographic damage of the spine and spinal mobility for individual patients with ankylosing spondylitis :b can assessment of spinal mobility be a proxy for radiographic evaluation?
264 1b BMJ,c 2005
338 a print2 rdacarrier
500 a Wanders, A Landewe, R Dougados, M Mielants, H van der Linden, Sj van der Heijde, D eng Evaluation Studies England 2005/06/17 09:00 Ann Rheum Dis. 2005 Jul;64(7):988-94.
520 a OBJECTIVE: To demonstrate the association between various measures of spinal mobility and radiographic damage of the spine in individual patients with ankylosing spondylitis, and to determine whether the assessment of spinal mobility can be a proxy for the assessment of radiographic damage. METHODS: Radiographic damage was assessed by the mSASSS. Cumulative probability plots combined the radiographic damage score of an individual patient with the corresponding score for nine spinal mobility measures. Receiver operating characteristic analysis was performed to determine the cut off level of every spinal mobility measure that discriminates best between the presence and absence of radiographic damage. Three arbitrary cut off levels for radiographic damage were investigated. Likelihood ratios were calculated to explore further the diagnostic properties of the spinal mobility measures. RESULTS: Cumulative probability plots showed an association between spinal mobility measures and radiographic damage for the individual patient. Irrespective of the chosen cut off level for radiographic progression, lateral spinal flexion and BASMI discriminated best between patients with and those without structural damage. Even the best discriminatory spinal mobility assessments misclassified a considerable proportion of patients (up to 20%). Intermalleolar distance performed worst (up to 30% misclassifications). Lateral spinal flexion best predicted the absence of radiographic damage, and a modified Schober test best predicted the presence of radiographic damage. CONCLUSION: This study unequivocally demonstrated a relationship between spinal mobility and radiographic damage. However, spinal mobility cannot be used as a proxy for radiographic evaluation in an individual patient.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaper0 (SwePub)3012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicine0 (SwePub)3012 hsv//eng
653 a Adult
653 a Cohort Studies
653 a Female
653 a Humans
653 a Male
653 a Movement
653 a Probability
653 a ROC Curve
653 a Spine/physiopathology/*radiography
653 a Spondylitis
653 a Ankylosing/physiopathology/*radiography
700a Landewe, R.4 aut
700a Dougados, M.4 aut
700a Mielants, H.4 aut
700a van der Linden, S.4 aut
700a van der Heijde, D.4 aut
773t Ann Rheum Disd : BMJg 64:7, s. 988-994q 64:7<988-94
773t Annals of the Rheumatic Diseasesd : BMJg 64:7, s. 988-994q 64:7<988-994x 0003-4967x 1468-2060
856u http://www.ncbi.nlm.nih.gov/pubmed/15958757
856u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15958757&dopt=Citation
856u https://ard.bmj.com/content/64/7/988.full.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-110944
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-80617
8564 8u https://doi.org/10.1136/ard.2004.029728

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Wanders, A.
Landewe, R.
Dougados, M.
Mielants, H.
van der Linden, ...
van der Heijde, ...
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