Search: WFRF:(Minkkinen Mikko)
> (2022) >
Routine revasculari...
Routine revascularization with percutaneous coronary intervention in patients with coronary artery disease undergoing transcatheter aortic valve implantation - the third Nordic Aortic Valve Intervention Trial - NOTION-3.
-
- Sabbah, Muhammad (author)
- Copenhagen University Hospital
-
- Veien, Karsten (author)
- Odense University Hospital
-
- Niemela, Matti (author)
- Oulu University Hospital
-
show more...
-
- Freeman, Phillip (author)
- Aalborg University Hospital
-
- Linder, Rickard (author)
- Karolinska Institutet,Danderyd Hospital
-
- Ioanes, Dan (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Sahlgrenska University Hospital
-
- Terkelsen, Christian Juhl (author)
- Danish Heart Foundation,Aarhus University Hospital
-
- Kajander, Olli A (author)
- Helsinki University Central Hospital,University of Helsinki
-
- Koul, Sasha (author)
- Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital
-
- Savontaus, Mikko (author)
- Turku University Hospital
-
- Karjalainen, Pasi (author)
- University of Helsinki,Helsinki University Central Hospital
-
- Erglis, Andrejs (author)
- University of Latvia
-
- Minkkinen, Mikko (author)
- University of Helsinki,Helsinki University Central Hospital
-
- Jørgensen, Troels (author)
- Copenhagen University Hospital
-
- Sondergaard, Lars (author)
- Copenhagen University Hospital,University of Copenhagen
-
- De Backer, Ole (author)
- Copenhagen University Hospital
-
- Engstrøm, Thomas (author)
- University of Copenhagen,Copenhagen University Hospital
-
- Lønborg, Jacob (author)
- Copenhagen University Hospital
-
show less...
-
(creator_code:org_t)
-
-
show more...
-
-
show less...
- Elsevier BV, 2022
- 2022
- English.
-
In: American heart journal. - : Elsevier BV. - 1097-6744 .- 0002-8703.
- Related links:
-
http://dx.doi.org/10... (free)
-
show more...
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
http://kipublication...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Coronary artery disease (CAD) frequently coexists with severe aortic valve stenosis (AS) in patients planned for transcatheter aortic valve implantation (TAVI). How to manage CAD in this patient population is still an unresolved question. In particular, it is still not known whether fractional flow reserve (FFR) guided revascularization with percutaneous coronary intervention (PCI) is superior to medical treatment for CAD in terms of clinical outcomes.The third Nordic Aortic Valve Intervention (NOTION-3) Trial is an open-label investigator-initiated, multicenter multinational trial planned to randomize 452 patients with severe AS and significant CAD to either FFR-guided PCI or medical treatment, in addition to TAVI. Patients are eligible for the study in the presence of at least one significant PCI-eligible coronary stenosis. A significant stenosis is defined as either FFR ≤0.80 and/or diameter stenosis >90%. The primary endpoint is a composite of first occurring all-cause mortality, myocardial infarction, or urgent revascularization (PCI or coronary artery bypass graft performed during unplanned hospital admission) until the last included patient have been followed for 1 year after the TAVI.NOTION-3 is a multicenter, multinational randomized trial aiming at comparing FFR-guided revascularization vs medical treatment of CAD in patients with severe AS planned for TAVI.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Sabbah, Muhammad
-
Veien, Karsten
-
Niemela, Matti
-
Freeman, Phillip
-
Linder, Rickard
-
Ioanes, Dan
-
show more...
-
Terkelsen, Chris ...
-
Kajander, Olli A
-
Koul, Sasha
-
Savontaus, Mikko
-
Karjalainen, Pas ...
-
Erglis, Andrejs
-
Minkkinen, Mikko
-
Jørgensen, Troel ...
-
Sondergaard, Lar ...
-
De Backer, Ole
-
Engstrøm, Thomas
-
Lønborg, Jacob
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
- Articles in the publication
-
American heart j ...
- By the university
-
University of Gothenburg
-
Lund University