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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 26800naa a2203229 4500 | |
| 001 | oai:DiVA.org:uu-378995 | |
| 003 | SwePub | |
| 008 | 190319s2019 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:814ff565-2d12-4adb-89f2-aeb72ef81451 | |
| 009 | oai:gup.ub.gu.se/285583 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3789952 URI |
| 024 | 7 | a https://doi.org/10.1093/eurheartj/ehy6532 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/814ff565-2d12-4adb-89f2-aeb72ef814512 URI |
| 024 | 7 | a https://gup.ub.gu.se/publication/2855832 URI |
| 040 | a (SwePub)uud (SwePub)lud (SwePub)gu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Pennells, Lisau Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England,University of Cambridge4 aut |
| 245 | 1 0 | a Equalization of four cardiovascular risk algorithms after systematic recalibration :b individual-participant meta-analysis of 86 prospective studies |
| 264 | c 2018-11-22 | |
| 264 | 1 | b Oxford University Press (OUP),c 2019 |
| 338 | a electronic2 rdacarrier | |
| 520 | a Aims: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after ‘recalibration’, a method that adapts risk algorithms to take account of differences in the risk characteristics of the populations being studied.Methods and results: Using individual-participant data on 360 737 participants without CVD at baseline in 86 prospective studies from 22 countries, we compared the Framingham risk score (FRS), Systematic COronary Risk Evaluation (SCORE), pooled cohort equations (PCE), and Reynolds risk score (RRS). We calculated measures of risk discrimination and calibration, and modelled clinical implications of initiating statin therapy in people judged to be at ‘high’ 10 year CVD risk. Original risk algorithms were recalibrated using the risk factor profile and CVD incidence of target populations. The four algorithms had similar risk discrimination. Before recalibration, FRS, SCORE, and PCE over-predicted CVD risk on average by 10%, 52%, and 41%, respectively, whereas RRS under-predicted by 10%. Original versions of algorithms classified 29–39% of individuals aged ≥40 years as high risk. By contrast, recalibration reduced this proportion to 22–24% for every algorithm. We estimated that to prevent one CVD event, it would be necessary to initiate statin therapy in 44–51 such individuals using original algorithms, in contrast to 37–39 individuals with recalibrated algorithms.Conclusion: Before recalibration, the clinical performance of four widely used CVD risk algorithms varied substantially. By contrast, simple recalibration nearly equalized their performance and improved modelled targeting of preventive action to clinical need. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
| 653 | a Cardiovascular disease | |
| 653 | a Risk prediction | |
| 653 | a Risk algorithms | |
| 653 | a Calibration | |
| 653 | a Discrimination | |
| 653 | a Calibration | |
| 653 | a Cardiovascular disease | |
| 653 | a Discrimination | |
| 653 | a Risk algorithms | |
| 653 | a Risk prediction | |
| 700 | 1 | a Kaptoge, Stephenu Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England4 aut |
| 700 | 1 | a Wood, Angelau Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England4 aut |
| 700 | 1 | a Sweeting, Mikeu Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England4 aut |
| 700 | 1 | a Zhao, Xiaohuiu Univ Cambridge, Dept Physiol Dev & Neurosci, Downing St, Cambridge CB2 3EG, England4 aut |
| 700 | 1 | a White, Ianu UCL, MRC Clin Trials Unit, 90 High Holborn, London WC1V 6LJ, England4 aut |
| 700 | 1 | a Burgess, Stephenu Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England;Univ Cambridge, Cambridge Inst Publ Hlth, MRC Biostat Unit, Forvie Site,Robinson Way, Cambridge CB2 0SR, England4 aut |
| 700 | 1 | a Willeit, Peteru Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England;Med Univ Innsbruck, Dept Neurol & Neurosurg, Anichstra 35, A-6020 Innsbruck, Austria4 aut |
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| 700 | 1 | a Khaw, Kay-Teeu Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England;EPICNOR, London, England;RANCHO, Utrecht, Netherlands4 aut |
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| 700 | 1 | a Kivimaki, Mikau UCL, Dept Epidemiol & Publ Hlth, 1-19 Torrington Pl, London WC1E 7HB, England;WHITE I, Viana Do Castelo, Portugal4 aut |
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| 700 | 1 | a Kuller, Lewis H.u Univ Pittsburgh, Dept Epidemiol, 200 Lothrop St, Pittsburgh, PA 15212 USA;MRFIT, Utrecht, Netherlands4 aut |
| 700 | 1 | a Brenner, Hermannu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Neuenheimer Feld 581, D-69120 Heidelberg, Germany;Heidelberg Univ, Grabengasse 1, D-69117 Heidelberg, Germany;WCWC, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Gillum, Richard F.u Howard Univ, Coll Med, Dept Med, 2041 Georgia Ave, Washington, DC 20060 USA;NHANES III, Utrecht, Netherlands4 aut |
| 700 | 1 | a Meisinger, Christau German Res Ctr Environm Hlth, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany;MONICA KORA2, Karachi, Pakistan;MONICA KORA3, Karachi, Pakistan4 aut |
| 700 | 1 | a Ford, Ianu Univ Glasgow, Inst Hlth & Wellbeing, Boyd Orr Bldg,Univ Ave, Glasgow G12 8QQ, Lanark, Scotland;WOSCOPS, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Knuiman, Matthew W.u Univ Western Australia, Sch Populat & Global Hlth, Fac Hlth & Med Sci, 35 Stirling Highway, Perth, WA 6009, Australia;BHS, London, England4 aut |
| 700 | 1 | a Rosengren, Annika,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xrosan |
| 700 | 1 | a Lawlor, Debbie A.u Univ Bristol, Dept Social Med, Bristol BS8 2PR, Avon, England4 aut |
| 700 | 1 | a Volzke, Henryu Ernst Moritz Arndt Univ Greifswald, Inst Community Med, Ellernholzstr 1-2, D-17489 Greifswald, Germany4 aut |
| 700 | 1 | a Cooper, Cyrusu Univ Southampton, MRC Lifecourse Epidemiol Unit, Tremona Rd, Southampton SO16 6YD, Hants, England4 aut |
| 700 | 1 | a Ibanez, Alejandro Marinu San Jose Norte Hlth Ctr, 16 Lugar Santuario Cabanas, Zaragoza 50013, Spain4 aut |
| 700 | 1 | a Casiglia, Edoardou Univ Padua, Dept Med, 2 Via Giustiniani, I-35128 Padua, Italy;CASTEL, New York, NY USA4 aut |
| 700 | 1 | a Kauhanen, Jussiu Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, 1 Yliopistonranta, Kuopio, Finland4 aut |
| 700 | 1 | a Cooper, Jackie A.u UCL, Ctr Cardiovasc Genet, 5 Univ St, London WC1E 6JF, England;NPHSII, Utrecht, Netherlands4 aut |
| 700 | 1 | a Rodriguez, Beatrizu Univ Hawaii, Dept Geriatr Med, 1960 East West Rd, Honolulu, HI 96822 USA;HONOL, Tokyo, Japan4 aut |
| 700 | 1 | a Sundström, Johan,c Professor,d 1971-u Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Klinisk epidemiologi4 aut0 (Swepub:uu)johasund |
| 700 | 1 | a Barrett-Connor, Elizabethu Univ Calif San Diego, 9500 Gilman Dr, La Jolla, CA 92093 USA4 aut |
| 700 | 1 | a Dankner, Rachelu Gertner Inst Epidemiol & Hlth Policy Res, Sheba Med Ctr, Unit Cardiovasc Epidemiol, IL-52621 Tel Hashomer, Israel;Tel Aviv Univ, Sch Publ Hlth, Sackler Fac Med, Dept Epidemiol & Prevent Med, IL-69978 Tel Aviv, Israel4 aut |
| 700 | 1 | a Nietert, Paul J.u Med Univ South Carolina, Dept Publ Hlth Sci, 135 Cannon St, Charleston, SC 29425 USA;CHARL, Greenville, SC USA4 aut |
| 700 | 1 | a Davidson, Karina W.u Columbia Univ Irving Med Ctr, Dept Med, 622 West 168th St, New York, NY 10032 USA4 aut |
| 700 | 1 | a Wallace, Robert B.u Univ Iowa, Coll Publ Hlth, 145 N Riverside Dr, Iowa City, IA 52242 USA4 aut |
| 700 | 1 | a Blazer, Dan G.u Duke Univ, Med Ctr, Dept Surg, 2301 Erwin Rd, Durham, NC 27707 USA4 aut |
| 700 | 1 | a Björkelund, Cecilia,d 1948u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xbjoce |
| 700 | 1 | a Donfrancesco, Chiarau ISS, Dysmetabol & Aging Associated Dis, Dept Cardiovasc, 299 Viale Regina Elena, I-00161 Rome, Italy;FINE IT, Heidelberg, Germany4 aut |
| 700 | 1 | a Krumholz, Harlan M.u Yale Sch Med, 1 Church St, New Haven, CT 06510 USA4 aut |
| 700 | 1 | a Nissinen, Aulikkiu Nat Inst Hlth & Welf, Mannerheimintie 166, Helsinki 00271, Finland;FINE FIN, Heidelberg, Germany4 aut |
| 700 | 1 | a Davis, Barry R.u Univ Texas Houston, Sch Publ Hlth, Dept Biostat, 1200 Pressler St, Houston, TX 77030 USA4 aut |
| 700 | 1 | a Coady, Seanu NHLBI, Div Cardiovasc Sci, 31 Ctr Dr, Bethesda, MD 20892 USA4 aut |
| 700 | 1 | a Whincup, Peter H.u St Georges Univ London, Populat Hlth Res Inst, Cranmer Terrace, London SW17 0RE, England;BRHS, Bridgewater, MA USA4 aut |
| 700 | 1 | a Jorgensen, Torbenu Res Ctr Prevent & Hlth, 5 Oster Farimagsgade, DK-1014 Copenhagen, Denmark;Univ Copenhagen, Dept Publ Hlth, 5 Oster Farimagsgade, DK-1014 Copenhagen, Denmark;Aalborg Univ, Fredrik Bajers Vej 5, DK-9100 Aalborg, Denmark4 aut |
| 700 | 1 | a Ducimetiere, Pierreu Univ Paris 05, Fac Med, 12 Rue Ecole Med, F-75006 Paris, France4 aut |
| 700 | 1 | a Trevisan, Mauriziou CUNY, Sch Med, City Coll New York, 160 Convent Ave, New York, NY 10031 USA;RIFLE, Utrecht, Netherlands4 aut |
| 700 | 1 | a Engström, Gunnaru Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)smi-gen |
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| 700 | 1 | a Meade, Tomw.u London Sch Hyg & Trop Med, Dept Noncommunicable Dis Epidemiol, Keppel St, London WC1E 7HT, England4 aut |
| 700 | 1 | a Visser, Marjoleinu Vrije Univ Amsterdam, VU Univ, Med Ctr, Dept Hlth Sci, De Boelelaan 1085, NL-1081 Amsterdam, Netherlands;LASA, Karachi, Pakistan4 aut |
| 700 | 1 | a Kromhout, Daanu Univ Grogingen, Univ Med Ctr Groningen, Dept Epidemiol, Hanzepl 1, NL-9713 Groningen, Netherlands4 aut |
| 700 | 1 | a Kiechl, Stefanu Med Univ Innsbruck, Dept Neurol & Neurosurg, Anichstra 35, A-6020 Innsbruck, Austria4 aut |
| 700 | 1 | a Daimon, Makotou Yamagata Univ, Fac Med, 1-4-12 Kojirakawa Machi, Yamagata 9908560, Japan4 aut |
| 700 | 1 | a Price, Jackie F.u Univ Edinburgh, Old Med Sch, Usher Inst Populat Hlth Sci & Informat, Teviot Pl, Edinburgh EH8 9AG, Midlothian, Scotland4 aut |
| 700 | 1 | a de la Camara, Agustin Gomezu Hosp 12 Octubre, Dept Clin Res, Av Cordoba, E-28041 Madrid, Spain;DRECE, Madrid, Spain4 aut |
| 700 | 1 | a Jukema, J. Wouteru Leiden Univ, Med Ctr, Dept Cardiol, Albinusdreef 2, NL-2333 Leiden, Netherlands4 aut |
| 700 | 1 | a Lamarche, Benoitu Univ Laval, Pavillon Ferdinand Vandry,2440 Hochelaga, Quebec City, PQ G1V 0A6, Canada4 aut |
| 700 | 1 | a Onat, Altanu Istanbul Univ, Cerrahpasa Fac Med, Dept Cardiol, TR-34452 Istanbul, Turkey4 aut |
| 700 | 1 | a Simons, Leon A.u UNSW, Fac Med, Sydney, NSW 2052, Australia4 aut |
| 700 | 1 | a Kavousi, Maryamu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Doctor Molewaterpl 40, NL-3015 Rotterdam, Netherlands4 aut |
| 700 | 1 | a Ben-Shlomo, Yoavu Univ Bristol, Bristol Neurosci, Queens Rd, Bristol BS8 1QU, Avon, England;CAPS, Oxford, England4 aut |
| 700 | 1 | a Gallacher, Johnu Univ Oxford, Warneford Hosp, Dept Psychiat, Warneford Lane, Oxford OX3 7JX, England;CAPS, Oxford, England4 aut |
| 700 | 1 | a Dekker, Jacqueline M.u Vrije Univ Amsterdam, Med Ctr, Inst Hlth & Care Res, De Boelelaan 1085, NL-1081 Amsterdam, Netherlands4 aut |
| 700 | 1 | a Arima, Hisatomiu Kyushu Univ, Nishi Ku, 744 Motooka, Fukuoka, Fukuoka 8190395, Japan4 aut |
| 700 | 1 | a Shara, Nawaru MedStar Hlth Res Inst, Dept Biostat & Bioinformat, 6525 Belcrest Rd, Hyattsville, MD 20782 USA4 aut |
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| 700 | 1 | a Roussel, Ronanu INSERM, Ctr Rech Cordeliers, 15 Rue Ecole Med, F-57006 Paris, France4 aut |
| 700 | 1 | a Brunner, Eric J.u UCL, Inst Epidemiol & Hlth, 1-19 Torrington Pl, London WC1E 7HB, England;WHITE II, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Koenig, Wolfgangu Tech Univ Munich, Deutsches Herzzentrum Munchen, 21 Arcisstr, D-80333 Munich, Germany;DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Biedersteiner Str 29, D-80802 Munich, Germany;MONICA KORA2, Karachi, Pakistan;MONICA KORA3, Karachi, Pakistan4 aut |
| 700 | 1 | a Sakurai, Masaruu Kanazawa Med Univ, Dept Social & Environm Med, 1-1 Daigaku, Uchinada, Ishikawa 9200293, Japan4 aut |
| 700 | 1 | a Pavlovic, Jelenau Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Doctor Molewaterpl 40, NL-3015 Rotterdam, Netherlands4 aut |
| 700 | 1 | a Gansevoort, Ron T.u Univ Grogingen, Univ Med Ctr Groningen, Dept Internal Med, Hanzeplein 1, NL-9713 Groningen, Netherlands4 aut |
| 700 | 1 | a Nagel, Dorotheau Univ Munich, Klinikum Univ Munchen, 15 Marchioninistr, D-81377 Munich, Germany;GRIPS, Tokyo, Japan4 aut |
| 700 | 1 | a Goldbourt, Uriu Tel Aviv Univ, Sch Publ Hlth, Sackler Fac Med, Dept Epidemiol & Prevent Med, IL-69978 Tel Aviv, Israel4 aut |
| 700 | 1 | a Barr, Elizabeth L. M.u Baker Heart & Diabet Inst, Clin Diabet & Epidemiol, 75 Commercial Rd, Melbourne, Vic 3004, Australia4 aut |
| 700 | 1 | a Palmieri, Luigiu ISS, Dysmetabol & Aging Associated Dis, Dept Cardiovasc, 299 Viale Regina Elena, I-00161 Rome, Italy;CUORE, Madrid, Spain4 aut |
| 700 | 1 | a Njolstad, Ingeru Univ Tromso, Dept Publ Hlth, Hansine Hansens Veg 18, Tromso, Norway4 aut |
| 700 | 1 | a Sato, Shinichiu Chiba Prefectural Inst Publ Hlth, Chuo Ku, 666-2 Nito No Machi, Chiba 2608715, Japan;IKNS, Isa Town, Bahrain4 aut |
| 700 | 1 | a Verschuren, W. M. Moniqueu Natl Inst Publ Hlth & Environm RIVM, Dept Determinants Chron Dis, Antonie Leeuwenhoeklaan 9, NL-3721 Bilthoven, Netherlands;MCVDRFP, Karachi, Pakistan;MORGEN, Utrecht, Netherlands4 aut |
| 700 | 1 | a Varghese, Cherian V.u WHO, Noncommunicable Dis Disabil Violence & Injury Pre, 20 Ave Appia, CH-1211 Geneva 27, Switzerland4 aut |
| 700 | 1 | a Graham, Ianu Univ Dublin, Coll Green, Trinity Coll Dublin, Sch Med, Dublin 2, Ireland4 aut |
| 700 | 1 | a Onuma, Oyereu WHO, Noncommunicable Dis Disabil Violence & Injury Pre, 20 Ave Appia, CH-1211 Geneva 27, Switzerland4 aut |
| 700 | 1 | a Greenland, Philipu Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, 420 East Super St, Chicago, IL 60611 USA4 aut |
| 700 | 1 | a Woodward, Marku Univ Oxford, George Inst Global Hlth, 75 George St, Oxford OX1 2BQ, England;Univ New South Wales, George Inst Global Hlth, 1 King St Newtown, Sydney, NSW 2042, Australia4 aut |
| 700 | 1 | a Ezzati, Majidu Imperial Coll London, Sch Publ Hlth, Fac Med, Norfolk Pl,St Marys Campus, London W2 1PG, England4 aut |
| 700 | 1 | a Psaty, Bruce M.u Univ Washington, Cardiovasc Hlth Res Unit, 1730 Minor Ave, Seattle, WA 98101 USA;CHS, Inver Grove Hts, MN USA4 aut |
| 700 | 1 | a Sattar, Naveedu Univ Glasgow, Inst Cardiovasc & Med Sci, 126 Univ Pl, Glasgow G12 8TA, Lanark, Scotland;MIDFAM, Karachi, Pakistan;WOSCOPS, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Jackson, Rodu Univ Auckland, Fac Med & Hlth Sci, 261 Morrin Rd, Auckland, New Zealand4 aut |
| 700 | 1 | a Ridker, Paul M.u Harvard Med Sch, Brigham & Womens Hosp, 900 Commonwealth Ave, Boston, MA 02215 USA;USPHS2, Viana Do Castelo, Portugal;WHS, Viana Do Castelo, Portugal4 aut |
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| 700 | 1 | a D'Agostino, Ralph B., Sr.u Boston Univ, Math & Stat Dept, 111 Cummington Mall, Boston, MA 02215 USA;FRAM, Boston, MA USA;FRAMOFF, Boston, MA USA4 aut |
| 700 | 1 | a Thompson, Simon G.u Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England4 aut |
| 700 | 1 | a Danesh, Johnu Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England4 aut |
| 700 | 1 | a Di Angelantonio, Emanueleu Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, England,University of Cambridge4 aut |
| 700 | 1 | a Tipping, Robert W.u AFTCAPS, Benn, Germany4 aut |
| 700 | 1 | a Simpson, Lara M.u ALLHAT, Bethesda, MD USA4 aut |
| 700 | 1 | a Pressel, Sara L.u ALLHAT, Bethesda, MD USA4 aut |
| 700 | 1 | a Couper, David J.u ARIC, Chapel Hill, NC USA4 aut |
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| 700 | 1 | a Matsushita, Kunihirou ARIC, Chapel Hill, NC USA4 aut |
| 700 | 1 | a Folsom, Aaron R.u ARIC, Chapel Hill, NC USA4 aut |
| 700 | 1 | a Shaw, Jonathan E.u AUSDIAB, Melbourne, Vic, Australia4 aut |
| 700 | 1 | a Magliano, Dianna J.u AUSDIAB, Melbourne, Vic, Australia4 aut |
| 700 | 1 | a Zimmet, Paul Z.u AUSDIAB, Melbourne, Vic, Australia4 aut |
| 700 | 1 | a Wannamethee, S. Goyau BRHS, Bridgewater, MA USA4 aut |
| 700 | 1 | a Willeit, Johannu BRUN, Bridgewater, MA USA4 aut |
| 700 | 1 | a Santer, Peteru BRUN, Bridgewater, MA USA4 aut |
| 700 | 1 | a Egger, Georgu BRUN, Bridgewater, MA USA4 aut |
| 700 | 1 | a Casas, Juan Pablou BWHHS, London, England4 aut |
| 700 | 1 | a Amuzu, Antointtteu BWHHS, London, England4 aut |
| 700 | 1 | a Tikhonoff, Valerieu CASTEL, New York, NY USA4 aut |
| 700 | 1 | a Sutherland, Susan E.u CHARL, Greenville, SC USA4 aut |
| 700 | 1 | a Cushman, Maryu CHS, Inver Grove Hts, MN USA4 aut |
| 700 | 1 | a Sogaard, Anne Johanneu CONOR, Tromso, Norway4 aut |
| 700 | 1 | a Haheim, Lise Lundu CONOR, Tromso, Norway4 aut |
| 700 | 1 | a Ariansen, Ingeru CONOR, Tromso, Norway4 aut |
| 700 | 1 | a Tybjaerg-Hansen, Anneu COPEN, Copenhagen, Denmark4 aut |
| 700 | 1 | a Jensen, Gorm B.u COPEN, Copenhagen, Denmark4 aut |
| 700 | 1 | a Schnohr, Peteru COPEN, Copenhagen, Denmark4 aut |
| 700 | 1 | a Giampaoli, Simonau CUORE, Madrid, Spain;FINE IT, Heidelberg, Germany4 aut |
| 700 | 1 | a Vanuzzo, Diegou CUORE, Madrid, Spain4 aut |
| 700 | 1 | a Panico, Salvatoreu CUORE, Madrid, Spain4 aut |
| 700 | 1 | a Balkau, Beverleyu DESIR, Madrid, Spain4 aut |
| 700 | 1 | a Bonnet, Fabriceu DESIR, Madrid, Spain4 aut |
| 700 | 1 | a Marre, Michelu DESIR, Madrid, Spain4 aut |
| 700 | 1 | a Herrera, Miguel Angel Rubiou DRECE, Madrid, Spain4 aut |
| 700 | 1 | a Friedlander, Yechiel4 aut |
| 700 | 1 | a McCallum, John4 aut |
| 700 | 1 | a McLachlan, Stelau EAS, Gothenburg, Sweden4 aut |
| 700 | 1 | a Guralnik, Jacku EPESEBOS, London, England;EPESEIOW, Baltimore, MD USA;EPESENCA, Oxford, England;EPESENHA, New York, NY USA4 aut |
| 700 | 1 | a Phillips, Caroline L.u EPESEBOS, London, England4 aut |
| 700 | 1 | a Wareham, Nicku EPICNOR, London, England4 aut |
| 700 | 1 | a Schottker, Benu ESTHER, Heidelberg, Germany4 aut |
| 700 | 1 | a Saum, Kai-Uweu ESTHER, Heidelberg, Germany4 aut |
| 700 | 1 | a Holleczek, Berndu ESTHER, Heidelberg, Germany4 aut |
| 700 | 1 | a Tolonen, Hannau FINE FIN, Heidelberg, Germany4 aut |
| 700 | 1 | a Jousilahti, Pekkau FINRISK 92 97, Heidelberg, Germany4 aut |
| 700 | 1 | a Harald, Kennetu FINRISK 92 97, Heidelberg, Germany4 aut |
| 700 | 1 | a Massaro, Joseph M.u FRAM, Boston, MA USA;FRAMOFF, Boston, MA USA4 aut |
| 700 | 1 | a Pencina, Michaelu FRAM, Boston, MA USA;FRAMOFF, Boston, MA USA4 aut |
| 700 | 1 | a Vasan, Ramachandranu FRAM, Boston, MA USA;FRAMOFF, Boston, MA USA4 aut |
| 700 | 1 | a Kayama, Takamasa4 aut |
| 700 | 1 | a Kato, Takeo4 aut |
| 700 | 1 | a Oizumi, Toshihide4 aut |
| 700 | 1 | a Jespersen, Jorgen4 aut |
| 700 | 1 | a Moller, Lars4 aut |
| 700 | 1 | a Bladbjerg, Else Marie4 aut |
| 700 | 1 | a Chetrit, A.u GOH, Belfast, Antrim, North Ireland4 aut |
| 700 | 1 | a Wilhelmsen, Larsu GOT043, Belfast, Antrim, North Ireland4 aut |
| 700 | 1 | a Lissner, Laurenu GOTOW, Belfast, Antrim, North Ireland4 aut |
| 700 | 1 | a Dennison, Elaineu HCS, Tokyo, Japan4 aut |
| 700 | 1 | a Kiyohara, Yutaka4 aut |
| 700 | 1 | a Ninomiya, Toshiharu4 aut |
| 700 | 1 | a Doi, Yasufumi4 aut |
| 700 | 1 | a Nijpels, Giel4 aut |
| 700 | 1 | a Stehouwer, Coen D. A.4 aut |
| 700 | 1 | a Kazumasa, Yamagishiu IKNS, Isa Town, Bahrain4 aut |
| 700 | 1 | a Iso, Hiroyasuu IKNS, Isa Town, Bahrain4 aut |
| 700 | 1 | a Vartiainen, Erkkiu FINRISK 92 97, Heidelberg, Germany;KAREL72, Isa Town, Bahrain4 aut |
| 700 | 1 | a Kurl, Sudhiru KIHD, Karachi, Pakistan4 aut |
| 700 | 1 | a Tuomainen, Tomi-Pekkau KIHD, Karachi, Pakistan4 aut |
| 700 | 1 | a Salonen, Jukka T.u KIHD, Karachi, Pakistan4 aut |
| 700 | 1 | a Deeg, Dorly J. H.u LASA, Karachi, Pakistan4 aut |
| 700 | 1 | a Nilsson, Peter M.4 aut |
| 700 | 1 | a Hedblad, Bo4 aut |
| 700 | 1 | a Melander, Olle4 aut |
| 700 | 1 | a De Boer, Ian H.4 aut |
| 700 | 1 | a DeFilippis, Andrew Paul4 aut |
| 700 | 1 | a Watt, Grahamu MIDFAM, Karachi, Pakistan4 aut |
| 700 | 1 | a Verschuren, Monique4 aut |
| 700 | 1 | a Tverdal, Aageu NCS, Utrecht, Netherlands4 aut |
| 700 | 1 | a Kirkland, Susanu NSHS, Newton, MA USA4 aut |
| 700 | 1 | a Shimbo, Daichiu NSHS, Newton, MA USA4 aut |
| 700 | 1 | a Shaffer, Jonathanu NSHS, Newton, MA USA4 aut |
| 700 | 1 | a Bakker, Stephan J. L.u PREVEND, Newton, MA USA4 aut |
| 700 | 1 | a van der Harst, Pimu PREVEND, Newton, MA USA4 aut |
| 700 | 1 | a Hillege, Hans L.u PREVEND, Newton, MA USA4 aut |
| 700 | 1 | a Dallongeville, Jeanu PRIME, Newton, MA USA4 aut |
| 700 | 1 | a Schulte, Helmutu PROCAM, Newton, MA USA4 aut |
| 700 | 1 | a Trompet, Stellau PROSPER, Newton, MA USA4 aut |
| 700 | 1 | a Smit, Roelof A. J.u PROSPER, Newton, MA USA4 aut |
| 700 | 1 | a Stott, David J.u PROSPER, Newton, MA USA4 aut |
| 700 | 1 | a Despres, Jean-Pierre4 aut |
| 700 | 1 | a Cantin, Bernard4 aut |
| 700 | 1 | a Dagenais, Gilles R.4 aut |
| 700 | 1 | a Laughlin, Gailu RANCHO, Utrecht, Netherlands4 aut |
| 700 | 1 | a Wingard, Deborahu RANCHO, Utrecht, Netherlands4 aut |
| 700 | 1 | a Aspelund, Thoru REYK, Reykjavik, Iceland4 aut |
| 700 | 1 | a Eiriksdottir, Gudnyu REYK, Reykjavik, Iceland4 aut |
| 700 | 1 | a Gudmundsson, Elias Freyr4 aut |
| 700 | 1 | a Ikram, Arfan4 aut |
| 700 | 1 | a van Rooij, Frank J. A.4 aut |
| 700 | 1 | a Franco, Oscar H.4 aut |
| 700 | 1 | a Rueda-Ochoa, Oscar L.4 aut |
| 700 | 1 | a Muka, Taulant4 aut |
| 700 | 1 | a Glisic, Marija4 aut |
| 700 | 1 | a Tunstall-Pedoe, Hugh4 aut |
| 700 | 1 | a Howard, Barbara V.4 aut |
| 700 | 1 | a Zhang, Ying4 aut |
| 700 | 1 | a Jolly, Stacey4 aut |
| 700 | 1 | a Davey-Smith, George4 aut |
| 700 | 1 | a Can, Gunay4 aut |
| 700 | 1 | a Yuksel, Husniye4 aut |
| 700 | 1 | a Nakagawa, Hideaki4 aut |
| 700 | 1 | a Morikawa, Yuko4 aut |
| 700 | 1 | a Miura, Katsuyuki4 aut |
| 700 | 1 | a Ingelsson, Martinu ULSAM, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Giedraitis, Vilmantasu ULSAM, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Gaziano, J. Michaelu USPHS2, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Shipley, Martinu WHITE I, Viana Do Castelo, Portugal;WHITE II, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Arndt, Volkeru WCWC, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Cook, Nancyu WHS, Viana Do Castelo, Portugal4 aut |
| 700 | 1 | a Geleijnse, Johanna M.u ZUTE, Viana Do Castelo, Portugal4 aut |
| 710 | 2 | a Univ Cambridge, Dept Publ Hlth & Primary Care, 2 Worts Causeway, Cambridge CB1 8RN, Englandb University of Cambridge4 org |
| 710 | 2 | a Emerging Risk Factors Collaboration |
| 773 | 0 | t European Heart Journald : Oxford University Press (OUP)g 40:7, s. 621-+q 40:7<621-+x 0195-668Xx 1522-9645 |
| 856 | 4 | u https://doi.org/10.1093/eurheartj/ehy653y Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1297230/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://doi.org/10.1093/eurheartj/ehy653 |
| 856 | 4 | u http://dx.doi.org/10.1093/eurheartj/ehy653x freey FULLTEXT |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-378995 |
| 856 | 4 8 | u https://doi.org/10.1093/eurheartj/ehy653 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/814ff565-2d12-4adb-89f2-aeb72ef81451 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/285583 |
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