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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008605naa a2200745 4500
001oai:DiVA.org:umu-206769
003SwePub
008230426s2023 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2067692 URI
0247 a https://doi.org/10.1515/cclm-2023-02092 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Bonroy, Carolienu Department of Diagnostic Sciences, Ghent University, Ghent, Belgium; Department of Laboratory Medicine, University Hospital Ghent, Ghent, Belgium4 aut
2451 0a Detection of antinuclear antibodies :b recommendations from EFLM, EASI and ICAP
264 c 2023-03-29
264 1b Walter de Gruyter,c 2023
338 a electronic2 rdacarrier
520 a Objectives: Antinuclear antibodies (ANA) are important for the diagnosis of various autoimmune diseases. ANA are usually detected by indirect immunofluorescence assay (IFA) using HEp-2 cells (HEp-2 IFA). There are many variables influencing HEp-2 IFA results, such as subjective visual reading, serum screening dilution, substrate manufacturing, microscope components and conjugate. Newer developments on ANA testing that offer novel features adopted by some clinical laboratories include automated computer-assisted diagnosis (CAD) systems and solid phase assays (SPA).Methods: A group of experts reviewed current literature and established recommendations on methodological aspects of ANA testing. This process was supported by a two round Delphi exercise. International expert groups that participated in this initiative included (i) the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group “Autoimmunity Testing”; (ii) the European Autoimmune Standardization Initiative (EASI); and (iii) the International Consensus on ANA Patterns (ICAP).Results: In total, 35 recommendations/statements related to (i) ANA testing and reporting by HEp-2 IFA; (ii) HEp-2 IFA methodological aspects including substrate/conjugate selection and the application of CAD systems; (iii) quality assurance; (iv) HEp-2 IFA validation/verification approaches and (v) SPA were formulated. Globally, 95% of all submitted scores in the final Delphi round were above 6 (moderately agree, agree or strongly agree) and 85% above 7 (agree and strongly agree), indicating strong international support for the proposed recommendations.Conclusions: These recommendations are an important step to achieve high quality ANA testing.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng
653 a antinuclear antibodies
653 a HEp-2 indirect immunofluorescence
653 a recommendations
7001 a Vercammen, Martineu Department of Laboratory Medicine, AZ Sint-Jan, Brugge, Belgium; Research Group REIM, Vrije Universiteit Brussel, Brussels, Belgium4 aut
7001 a Fierz, Walteru Schweizerischer Verband der Diagnostikindustrie (SVDI-ASID), Bern, Switzerland4 aut
7001 a Andrade, Luis E.C.u Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil; Immunology Division, Fleury Medicine and Health Laboratories, Sao Paulo, Brazil4 aut
7001 a Van Hoovels, Lieveu Department of Laboratory Medicine, OLV Hospital, Aalst, Belgium; Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium4 aut
7001 a Infantino, Mariau Immunology and Allergology Laboratory, S. Giovanni di Dio Hospital, Florence, Italy4 aut
7001 a Fritzler, Marvin J.u Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Calgary, Canada4 aut
7001 a Bogdanos, Dimitriosu Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, University General Hospital of Larissa, Larissa, Greece4 aut
7001 a Kozmar, Anau Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Zagreb, Croatia4 aut
7001 a Nespola, Benoitu Laboratory of Immunology, Hôpitaux Universitaires de Strasbourg, Strasbourg, France4 aut
7001 a Broeders, Sylviau Quality of Laboratories, Sciensano, Ixelles, Belgium4 aut
7001 a Patel, Dinau UK NEQAS Immunology, Immunochemistry and Allergy, Sheffield Teaching Hospitals, Sheffield, United Kingdom4 aut
7001 a Herold, Manfredu Department of Internal Medicine II, Rheumatology Laboratory, Medical University of Innsbruck, Innsbruck, Austria4 aut
7001 a Zheng, Bingu Department of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China4 aut
7001 a Chan, Eric Y.T.u Department of Pathology, Queen Mary Hospital, Hong Kong, Hong Kong4 aut
7001 a Uibo, Raivou Department of Immunology, Medical Faculty, University of Tartu, Tartu, Estonia4 aut
7001 a Haapala, Anna-Maijau Department of Immunology, Fimlab Laboratories, Tampere, Finland4 aut
7001 a Musset, Lucileu Department of Immunology, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France4 aut
7001 a Sack, Ulrichu Medical Faculty, Leipzig University, Leipzig, Germany4 aut
7001 a Nagy, Gaboru Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary4 aut
7001 a Sundic, Tatjanau Department of Immunology and Transfusion Medicine, Haugesund Hospital, Helse Fonna, Haugesund, Norway4 aut
7001 a Fischer, Katarzynau Individual Laboratory for Rheumatologic Diagnostics, Pomeranian Medical University in Szczecin, Szczecin, Poland4 aut
7001 a Rego De Sousa, Maria-Joséu Immunopathology and Autoimmunity Department, Centro de Medicina Laboratorial Germano de Sousa, Lisbon, Portugal4 aut
7001 a Vargas, Maria Luisau Immunology, Hospital Universitario de Badajoz, Badajoz, Spain4 aut
7001 a Eriksson, Catharina,d 1955-u Umeå universitet,Institutionen för klinisk mikrobiologi4 aut0 (Swepub:umu)caaern74
7001 a Heijnen, Ingmaru Immunology, Laboratory Medicine, University Hospital Basel, Basel, Switzerland4 aut
7001 a García-De La Torre, Ignaciou Department of Immunology and Rheumatology, Hospital General de Occidente, Universidad de Guadalajara, Guadalajara, Mexico4 aut
7001 a Carballo, Orlando Gabrielu Laboratory of Immunology, Hospital Carlos G. Durand, Buenos Aires, Argentina; Department of Microbiology and Immunology, Instituto Universitario, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina4 aut
7001 a Satoh, Minoruu Department of Human, Information and Life Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan; Department of Medicine, Kitakyushu Yahata-Higashi Hospital, Kitakyushu, Japan4 aut
7001 a Kim, Kyeong-Heeu Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, South Korea4 aut
7001 a Chan, Edward K.L.u Department of Oral Biology, University of Florida, FL, Gainesville, United States4 aut
7001 a Damoiseaux, Janu Central Diagnostic Laboratory, Maastricht University Medical Center, Maastricht, Netherlands4 aut
7001 a Lopez-Hoyos, Marcosu Immunology Service, University Hospital Marques de Valdecilla-IDIVAL, University of Cantabria, Santander, Spain4 aut
7001 a Bossuyt, Xavieru Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium; Department of Laboratory Medicine, University Hospital Leuven, Leuven, Belgium4 aut
7102 a Department of Diagnostic Sciences, Ghent University, Ghent, Belgium; Department of Laboratory Medicine, University Hospital Ghent, Ghent, Belgiumb Department of Laboratory Medicine, AZ Sint-Jan, Brugge, Belgium; Research Group REIM, Vrije Universiteit Brussel, Brussels, Belgium4 org
7730 t Clinical Chemistry and Laboratory Medicined : Walter de Gruyterg 61:7, s. 1167-1198q 61:7<1167-1198x 1434-6621x 1437-4331
8564 u https://doi.org/10.1515/cclm-2023-0209y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1753344/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206769
8564 8u https://doi.org/10.1515/cclm-2023-0209

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