Natural-Cause Mortality and Long-Term Exposure to Particle Components: An Analysis of 19 European Cohorts within the Multi-Center ESCAPE Project

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Fältnamn	Indikatorer	Metadata
000		06602naa a2201237 4500
001		oai:DiVA.org:su-119246
003		SwePub
008		150803s2015 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:131583610
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1192462 URI
024	7	a https://doi.org/10.1289/ehp.14080952 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1315836102 URI
040		a (SwePub)sud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a for2 swepub-publicationtype
100	1	a Beelen, Rob4 aut
245	1 0	a Natural-Cause Mortality and Long-Term Exposure to Particle Components :b An Analysis of 19 European Cohorts within the Multi-Center ESCAPE Project
264	1	b Environmental Health Perspectives,c 2015
338		a print2 rdacarrier
520		a Background: Studies have shown associations between mortality and long-term exposure to particulate matter air pollution. Few cohort studies have estimated the effects of the elemental composition of particulate matter on mortality. Objectives: Our aim was to study the association between natural-cause mortality and long-term exposure to elemental components of particulate matter. Methods: Mortality and confounder data from 19 European cohort studies were used. Residential exposure to eight a priori-selected components of particulate matter ( PM) was characterized following a strictly standardized protocol. Annual average concentrations of copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc within PM size fractions <= 2.5 mu m (PM2.5) and <= 10 mu m (PM10) were estimated using land-use regression models. Cohort-specific statistical analyses of the associations between mortality and air pollution were conducted using Cox proportional hazards models using a common protocol followed by meta-analysis. Results: The total study population consisted of 291,816 participants, of whom 25,466 died from a natural cause during follow-up (average time of follow-up, 14.3 years). Hazard ratios were positive for almost all elements and statistically significant for PM2.5 sulfur (1.14; 95% CI: 1.06, 1.23 per 200ng/m(3)). In a two-pollutant model, the association with PM2.5 sulfur was robust to adjustment for PM2.5 mass, whereas the association with PM2.5 mass was reduced. Conclusions: Long-term exposure to PM2.5 sulfur was associated with natural-cause mortality. This association was robust to adjustment for other pollutants and PM2.5.
650	7	a NATURVETENSKAPx Geovetenskap och miljövetenskap0 (SwePub)1052 hsv//swe
650	7	a NATURAL SCIENCESx Earth and Related Environmental Sciences0 (SwePub)1052 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskap0 (SwePub)3032 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciences0 (SwePub)3032 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaper0 (SwePub)3012 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicine0 (SwePub)3012 hsv//eng
700	1	a Hoek, Gerard4 aut
700	1	a Raaschou-Nielsen, Ole4 aut
700	1	a Stafoggia, Massimo4 aut
700	1	a Andersen, Zorana Jovanovic4 aut
700	1	a Weinmayr, Gudrun4 aut
700	1	a Hoffmann, Barbara4 aut
700	1	a Wolf, Kathrin4 aut
700	1	a Samoli, Evangelia4 aut
700	1	a Fischer, Paul H.4 aut
700	1	a Nieuwenhuijsen, Mark J.4 aut
700	1	a Xun, Wei W.4 aut
700	1	a Katsouyanni, Klea4 aut
700	1	a Dimakopoulou, Konstantina4 aut
700	1	a Marcon, Alessandro4 aut
700	1	a Vartiainen, Erkki4 aut
700	1	a Lanki, Timo4 aut
700	1	a Yli-Tuomi, Tarja4 aut
700	1	a Oftedal, Bente4 aut
700	1	a Schwarze, Per E.4 aut
700	1	a Nafstad, Per4 aut
700	1	a De Faire, Ulfu Karolinska Institutet4 aut
700	1	a Pedersen, Nancy L.u Karolinska Institutet4 aut
700	1	a Otstenson, Claes-Goran4 aut
700	1	a Fratiglioni, Laurau Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)4 aut
700	1	a Penell, Johanna4 aut
700	1	a Korek, Michal4 aut
700	1	a Pershagen, Goranu Karolinska Institutet4 aut
700	1	a Eriksen, Kirsten Thorup4 aut
700	1	a Overvad, Kim4 aut
700	1	a Sorensen, Mette4 aut
700	1	a Eeftens, Marloes4 aut
700	1	a Peeters, Petra H.4 aut
700	1	a Meliefste, Kees4 aut
700	1	a Wang, Meng4 aut
700	1	a Bueno-de-Mesquita, H. Bas4 aut
700	1	a Sugiri, Dorothea4 aut
700	1	a Kramer, Ursula4 aut
700	1	a Heinrich, Joachim4 aut
700	1	a de Hoogh, Kees4 aut
700	1	a Key, Timothy4 aut
700	1	a Peters, Annette4 aut
700	1	a Hampel, Regina4 aut
700	1	a Concin, Hans4 aut
700	1	a Nagel, Gabriele4 aut
700	1	a Jaensch, Andrea4 aut
700	1	a Ineichen, Alex4 aut
700	1	a Tsai, Ming-Yi4 aut
700	1	a Schaffner, Emmanuel4 aut
700	1	a Probst-Hensch, Nicole M.4 aut
700	1	a Schindler, Christian4 aut
700	1	a Ragettli, Martina S.4 aut
700	1	a Vilier, Alice4 aut
700	1	a Clavel-Chapelon, Francoise4 aut
700	1	a Declercq, Christophe4 aut
700	1	a Ricceri, Fulvio4 aut
700	1	a Sacerdote, Carlotta4 aut
700	1	a Galassi, Claudia4 aut
700	1	a Migliore, Enrica4 aut
700	1	a Ranzi, Andrea4 aut
700	1	a Cesaroni, Giulia4 aut
700	1	a Badaloni, Chiara4 aut
700	1	a Forastiere, Francesco4 aut
700	1	a Katsoulis, Michail4 aut
700	1	a Trichopoulou, Antonia4 aut
700	1	a Keuken, Menno4 aut
700	1	a Jedynska, Aleksandra4 aut
700	1	a Kooter, Ingeborg M.4 aut
700	1	a Kukkonen, Jaakko4 aut
700	1	a Sokhi, Ranjeet S.4 aut
700	1	a Vineis, Paolo4 aut
700	1	a Brunekreef, Bert4 aut
710	2	a Karolinska Institutetb Centrum för forskning om äldre och åldrande (ARC), (tills m KI)4 org
773	0	t Journal of Environmental Health Perspectivesd : Environmental Health Perspectivesg 123:6, s. 525-533q 123:6<525-533x 0091-6765x 1552-9924
856	4	u https://doi.org/10.1289/ehp.1408095y Fulltext
856	4	u https://doi.org/10.1289/ehp.1408095
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-119246
856	4 8	u https://doi.org/10.1289/ehp.1408095
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:131583610

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Av författaren/redakt...: Beelen, Rob; Hoek, Gerard; Raaschou-Nielsen ...; Stafoggia, Massi ...; Andersen, Zorana ...; Weinmayr, Gudrun; visa fler...; Hoffmann, Barbar ...; Wolf, Kathrin; Samoli, Evangeli ...; Fischer, Paul H.; Nieuwenhuijsen, ...; Xun, Wei W.; Katsouyanni, Kle ...; Dimakopoulou, Ko ...; Marcon, Alessand ...; Vartiainen, Erkk ...; Lanki, Timo; Yli-Tuomi, Tarja; Oftedal, Bente; Schwarze, Per E.; Nafstad, Per; De Faire, Ulf; Pedersen, Nancy ...; Otstenson, Claes ...; Fratiglioni, Lau ...; Penell, Johanna; Korek, Michal; Pershagen, Goran; Eriksen, Kirsten ...; Overvad, Kim; Sorensen, Mette; Eeftens, Marloes; Peeters, Petra H ...; Meliefste, Kees; Wang, Meng; Bueno-de-Mesquit ...; Sugiri, Dorothea; Kramer, Ursula; Heinrich, Joachi ...; de Hoogh, Kees; Key, Timothy; Peters, Annette; Hampel, Regina; Concin, Hans; Nagel, Gabriele; Jaensch, Andrea; Ineichen, Alex; Tsai, Ming-Yi; Schaffner, Emman ...; Probst-Hensch, N ...; Schindler, Chris ...; Ragettli, Martin ...; Vilier, Alice; Clavel-Chapelon, ...; Declercq, Christ ...; Ricceri, Fulvio; Sacerdote, Carlo ...; Galassi, Claudia; Migliore, Enrica; Ranzi, Andrea; Cesaroni, Giulia; Badaloni, Chiara; Forastiere, Fran ...; Katsoulis, Micha ...; Trichopoulou, An ...; Keuken, Menno; Jedynska, Aleksa ...; Kooter, Ingeborg ...; Kukkonen, Jaakko; Sokhi, Ranjeet S ...; Vineis, Paolo; Brunekreef, Bert; visa färre...

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