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Risk Factors, Subse...
Risk Factors, Subsequent Disease Onset, and Prognostic Impact of Myocardial Infarction and Atrial Fibrillation
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- Camen, Stephan (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Luebeck, Hamburg, Germany
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- Csengeri, Dora (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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- Geelhoed, Bastiaan (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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- Niiranen, Teemu (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland; Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland
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- Gianfagna, Francesco (författare)
- Research Center in Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy; Mediterranea Cardiocentro, Napoli, Italy
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- Vishram-Nielsen, Julie K. (författare)
- Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Denmark; Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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- Costanzo, Simona (författare)
- Department of Epidemiology and Prevention, Istituto Neurologico Mediterraneo è un Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, Pozzilli, Italy
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- Söderberg, Stefan (författare)
- Umeå universitet,Avdelningen för medicin,Heart Centre, Umeå University, Umeå, Sweden
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- Vartiainen, Erkki (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland
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- Börschel, Christin S. (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Luebeck, Hamburg, Germany
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- Donati, Maria Benedetta (författare)
- Department of Epidemiology and Prevention, Istituto Neurologico Mediterraneo è un Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, Pozzilli, Italy
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- Løchen, Maja-Lisa (författare)
- Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway
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- Ojeda, Francisco M. (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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- Kontto, Jukka (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland
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- Mathiesen, Ellisiv B. (författare)
- Brain and Circulation Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway; Department of Neurology, University Hospital of North Norway, Tromsø, Norway
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- Jensen, Steen M. (författare)
- Umeå universitet,Avdelningen för medicin,Heart Centre, Umeå University, Umeå, Sweden
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- Koenig, Wolfgang (författare)
- German Heart Center Munich, Technical University of Munich, Munich, Germany; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany; Institute of Epidemiology and Medical Biometry, University of Ulm, Germany
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- Kee, Frank (författare)
- Centre for Public Health, Queens University of Belfast, Belfast, United Kingdom
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- de Gaetano, Giovanni (författare)
- Department of Epidemiology and Prevention, Istituto Neurologico Mediterraneo è un Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, Pozzilli, Italy
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- Zeller, Tanja (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Luebeck, Hamburg, Germany
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- Jørgensen, Torben (författare)
- Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Denmark; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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- Tunstall-Pedoe, Hugh (författare)
- Cardiovascular Epidemiology Unit, Institute of Cardiovascular Research, University of Dundee, Dundee, United Kingdom
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- Blankenberg, Stefan (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Luebeck, Hamburg, Germany
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- Kuulasmaa, Kari (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland
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- Linneberg, Allan (författare)
- Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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- Salomaa, Veikko (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland
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- Iacoviello, Licia (författare)
- Research Center in Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy; Department of Epidemiology and Prevention, Istituto Neurologico Mediterraneo è un Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Neuromed, Pozzilli, Italy
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- Schnabel, Renate B. (författare)
- Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Luebeck, Hamburg, Germany
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(creator_code:org_t)
- American Heart Association, 2022
- 2022
- Engelska.
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Ingår i: Journal of the American Heart Association. - : American Heart Association. - 2047-9980. ; 11:7
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Although myocardial infarction (MI) and atrial fibrillation (AF) are frequent comorbidities and share common cardiovascular risk factors, the direction and strength of the association of the risk factors with disease onset, subsequent disease incidence, and mortality are not completely understood.METHODS AND RESULTS: In pooled multivariable Cox regression analyses, we examined temporal relations of disease onset and identified predictors of MI, AF, and all-cause mortality in 108 363 individuals (median age, 46.0 years; 48.2% men) free of MI and AF at baseline from 6 European population-based cohorts. During a maximum follow-up of 10.0 years, 3558 (3.3%) individuals were diagnosed exclusively with MI, 1922 (1.8%) with AF but no MI, and 491 (0.5%) individuals developed both MI and AF. Association of sex, systolic blood pressure, antihypertensive treatment, and diabetes appeared to be stronger with incident MI than with AF, whereas increasing age and body mass index showed a higher risk for incident AF. Total cholesterol and daily smoking were significantly related to incident MI but not AF. Combined population attributable fraction of cardiovascular risk factors was >70% for incident MI, whereas it was only 27% for AF. Subsequent MI after AF (hazard ratio [HR], 1.68; 95% CI, 1.03–2.74) and subsequent AF after MI (HR, 1.75; 95% CI, 1.31–2.34) both significantly increased overall mortality risk.CONCLUSIONS: We observed different associations of cardiovascular risk factors with both diseases indicating distinct pathophysiological pathways. Subsequent diagnoses of MI and AF significantly increased mortality risk.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- atrial fibrillation
- cohort study
- mortality
- myocardial infarction
- risk factors
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Camen, Stephan
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Csengeri, Dora
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Geelhoed, Bastia ...
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Niiranen, Teemu
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Gianfagna, Franc ...
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Vishram-Nielsen, ...
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Costanzo, Simona
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Söderberg, Stefa ...
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Vartiainen, Erkk ...
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Börschel, Christ ...
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Donati, Maria Be ...
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Løchen, Maja-Lis ...
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Ojeda, Francisco ...
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Kontto, Jukka
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Mathiesen, Ellis ...
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Jensen, Steen M.
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Koenig, Wolfgang
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Kee, Frank
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de Gaetano, Giov ...
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Zeller, Tanja
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Jørgensen, Torbe ...
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Tunstall-Pedoe, ...
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Blankenberg, Ste ...
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Kuulasmaa, Kari
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Linneberg, Allan
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Salomaa, Veikko
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Iacoviello, Lici ...
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Schnabel, Renate ...
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