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FältnamnIndikatorerMetadata
00005268naa a2200505 4500
001oai:DiVA.org:uu-527499
003SwePub
008240503s2024 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5274992 URI
0247 a https://doi.org/10.1136/bmjgh-2023-0142942 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Marklund, Mattiu Uppsala universitet,Klinisk nutrition och metabolism,George Inst Global Hlth, Food Policy, Newtown, NSW, Australia.;Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA.;Johns Hopkins Univ, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD 21218 USA.4 aut0 (Swepub:uu)matma701
2451 0a Estimated health benefits, costs and cost-effectiveness of eliminating industrial trans-fatty acids in Nigeria :b cost-effectiveness analysis
264 1b BMJ Publishing Group Ltd,c 2024
338 a electronic2 rdacarrier
520 a Introduction: Nigeria is committed to reducing industrial trans-fatty acids (iTFA) from the food supply, but the potential health gains, costs and cost-effectiveness are unknown.Methods: The effect on ischaemic heart disease (IHD) burden, costs and cost-effectiveness of a mandatory iTFA limit (≤2% of all fats) for foods in Nigeria were estimated using Markov cohort models. Data on demographics, IHD epidemiology and trans-fatty acid intake were derived from the 2019 Global Burden of Disease Study. Avoided IHD events and deaths; health-adjusted life years (HALYs) gained; and healthcare, policy implementation and net costs were estimated over 10 years and the population's lifetime. Incremental cost-effectiveness ratios using net costs and HALYs gained (both discounted at 3%) were used to assess cost-effectiveness.Results: Over the first 10 years, a mandatory iTFA limit (assumed to eliminate iTFA intake) was estimated to prevent 9996 (95% uncertainty interval: 8870 to 11 118) IHD deaths and 66 569 (58 862 to 74 083) IHD events, and to save US$90 million (78 to 102) in healthcare costs. The corresponding lifetime estimates were 259 934 (228 736 to 290 191), 479 308 (95% UI 420 472 to 538 177) and 518 (450 to 587). Policy implementation costs were estimated at US$17 million (11 to 23) over the first 10 years, and US$26 million USD (19 to 33) over the population's lifetime. The intervention was estimated to be cost-saving, and findings were robust across several deterministic sensitivity analyses.Conclusion: Our findings support mandating a limit of iTFAs as a cost-saving strategy to reduce the IHD burden in Nigeria.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi0 (SwePub)303012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Health Care Service and Management, Health Policy and Services and Health Economy0 (SwePub)303012 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
653 a Health economics
653 a Nutrition
653 a Public Health
653 a Cardiovascular disease
7001 a Aminde, Leopold N.u Griffith Univ, Sch Med & Dent, Gold Coast, Qld, Australia.4 aut
7001 a Wanjau, Mary Njeriu Griffith Univ, Sch Med & Dent, Gold Coast, Qld, Australia.4 aut
7001 a Ale, Boni M.u Univ Abuja Teaching Hosp, Cardiovasc Res Unit, Gwagwalada, Abuja, Nigeria.;Holo Healthcare, Nairobi, Kenya.4 aut
7001 a Ojo, Adedayo E.u Univ Abuja Teaching Hosp, Cardiovasc Res Unit, Gwagwalada, Abuja, Nigeria.;Univ Med Ctr Utrecht, Dept Epidemiol & Global Hlth, Utrecht, Netherlands.4 aut
7001 a Okoro, Clementina E.u Fed Capital Terr Primary Hlth Care Board, Abuja, Nigeria.4 aut
7001 a Adegboye, Abimbolau Natl Agcy Food & Drug Adm & Control, Abuja, Federal Capital, Nigeria.4 aut
7001 a Huang, Lipingu George Inst Global Hlth, Food Policy, Newtown, NSW, Australia.4 aut
7001 a Veerman, J. Lennertu Griffith Univ, Sch Med & Dent, Gold Coast, Qld, Australia.4 aut
7001 a Wu, Jason H. Y.u George Inst Global Hlth, Food Policy, Newtown, NSW, Australia.;Univ New South Wales, Sch Publ Hlth & Community Med, Sydney, NSW, Australia.4 aut
7001 a Huffman, Mark D.u George Inst Global Hlth, Food Policy, Newtown, NSW, Australia.;Washington Univ St Louis, St Louis, MO USA.4 aut
7001 a Ojji, Dike B.u Univ Abuja Teaching Hosp, Cardiovasc Res Unit, Gwagwalada, Abuja, Nigeria.;Univ Abuja, Fac Clin Sci, Dept Internal Med, Abuja, Federal Capital, Nigeria.4 aut
7102 a Uppsala universitetb Klinisk nutrition och metabolism4 org
7730 t BMJ Global Healthd : BMJ Publishing Group Ltdg 9:4q 9:4x 2059-7908
8564 u https://doi.org/10.1136/bmjgh-2023-014294y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1855900/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-527499
8564 8u https://doi.org/10.1136/bmjgh-2023-014294

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