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Cognitive disorders in patients with chronic kidney disease: Approaches to prevention and treatment

Pepin, Marion (author)
Paris Saclay Univ, France; Versailles St Quentin En Yvelines Univ, France; Ambroise Pare Univ Hosp, France
Klimkowicz-Mrowiec, Aleksandra (author)
Jagiellonian Univ Med Coll, Poland
Godefroy, Olivier (author)
Jules Verne Univ Picardie UPJV, France; Jules Verne Univ Picardie UPJV, France
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Delgado, Pilar (author)
Univ Autonoma Barcelona, Spain
Carriazo, Sol (author)
Autonomous Univ Madrid UAM, Spain
Ferreira, Ana Carina (author)
Ctr Hosp & Univ Lisboa, Portugal; Univ Nova Lisboa, Portugal
Golenia, Aleksandra (author)
Med Univ Warsaw, Poland
Malyszko, Jolanta (author)
Med Univ Warsaw, Poland
Grodzicki, Tomasz (author)
Jagiellonian Univ Med Coll, Poland
Giannakou, Konstantinos (author)
European Univ Cyprus, Cyprus
Paolisso, Giuseppe (author)
Univ Campania Luigi Vanvitelli, Italy; Int Med Univ, Italy
Barbieri, Michelangela (author)
Univ Campania Luigi Vanvitelli, Italy
Garneata, Liliana (author)
Carol Davila Univ Med & Pharm, Romania
Mocanu, Carmen Antonia (author)
Carol Davila Univ Med & Pharm, Romania
Liabeuf, Sophie (author)
Amiens Univ, France; Univ Picardie Jules Verne, France
Spasovski, Goce (author)
Univ St Cyril & Methodius, North Macedonia
Zoccali, Carmine (author)
Renal Res Inst, NY USA; Assoc Ipertens Nefrol Trapianto Renale, Italy
Bruchfeld, Annette (author)
Karolinska Institutet,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Njurmedicinska kliniken US,Karolinska Univ Hosp, Sweden
Farinha, Ana (author)
Ctr Hosp Setubal, Portugal
Arici, Mustafa (author)
Hacetepe Univ, Turkiye
Capasso, Giovambattista (author)
Biogem Mol Biol & Genet Res Inst, Italy; Univ Campania, Italy
Wiecek, Andrzej A. (author)
Med Univ Silesia, Poland
Massy, Ziad (author)
Paris Saclay Univ, France; Versailles St Quentin En Yvelines Univ, France; Ambroise Pare Univ Hosp, France
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 (creator_code:org_t)
WILEY, 2023
2023
English.
In: European Journal of Neurology. - : WILEY. - 1351-5101 .- 1468-1331. ; 30:9, s. 2899-2911
Related links:
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https://doi.org/10.1...
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  • Research review (peer-reviewed)
Abstract Subject headings
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  • Background: Cognitive impairment is common in patients with chronic kidney disease (CKD), and early intervention may prevent the progression of this condition. Methods: Here, we review interventions for the complications of CKD (anemia, secondary hyperparathyroidism, metabolic acidosis, harmful effects of dialysis, the accumulation of uremic toxins) and for prevention of vascular events, interventions that may potentially be protective against cognitive impairment. Furthermore, we discuss nonpharmacological and pharmacological methods to prevent cognitive impairment and/or minimize the latters impact on CKD patients daily lives. Results: A particular attention on kidney function assessment is suggested during work-up for cognitive impairment. Different approaches are promising to reduce cognitive burden in patients with CKD but the availabe dedicated data are scarce. Conclusions: There is a need for studies assessing the effect of interventions on the cognitive function of patients with CKD.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)

Keyword

chronic kidney disease; cognition; dialysis; glomerular filtration rate; vascular risk factors

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