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FältnamnIndikatorerMetadata
00006334naa a2200673 4500
001oai:lup.lub.lu.se:6505d680-fb46-459f-8e54-d99ef382d314
003SwePub
008180306s2018 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:137582019
0247 a https://lup.lub.lu.se/record/6505d680-fb46-459f-8e54-d99ef382d3142 URI
0247 a https://doi.org/10.1186/s12995-018-0186-92 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1375820192 URI
040 a (SwePub)lud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a for2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Budnik, Lygia Thereseu University Medical Center Hamburg-Eppendorf4 aut
2451 0a Diagnosis, monitoring and prevention of exposure-related non-communicable diseases in the living and working environment : DiMoPEx-project is designed to determine the impacts of environmental exposure on human health
264 c 2018-02-05
264 1b Springer Science and Business Media LLC,c 2018
300 a 22 s.
520 a The WHO has ranked environmental hazardous exposures in the living and working environment among the top risk factors for chronic disease mortality. Worldwide, about 40 million people die each year from noncommunicable diseases (NCDs) including cancer, diabetes, and chronic cardiovascular, neurological and lung diseases. The exposure to ambient pollution in the living and working environment is exacerbated by individual susceptibilities and lifestyle-driven factors to produce complex and complicated NCD etiologies. Research addressing the links between environmental exposure and disease prevalence is key for prevention of the pandemic increase in NCD morbidity and mortality. However, the long latency, the chronic course of some diseases and the necessity to address cumulative exposures over very long periods does mean that it is often difficult to identify causal environmental exposures. EU-funded COST Action DiMoPEx is developing new concepts for a better understanding of health-environment (including gene-environment) interactions in the etiology of NCDs. The overarching idea is to teach and train scientists and physicians to learn how to include efficient and valid exposure assessments in their research and in their clinical practice in current and future cooperative projects. DiMoPEx partners have identified some of the emerging research needs, which include the lack of evidence-based exposure data and the need for human-equivalent animal models mirroring human lifespan and low-dose cumulative exposures. Utilizing an interdisciplinary approach incorporating seven working groups, DiMoPEx will focus on aspects of air pollution with particulate matter including dust and fibers and on exposure to low doses of solvents and sensitizing agents. Biomarkers of early exposure and their associated effects as indicators of disease-derived information will be tested and standardized within individual projects. Risks arising from some NCDs, like pneumoconioses, cancers and allergies, are predictable and preventable. Consequently, preventative action could lead to decreasing disease morbidity and mortality for many of the NCDs that are of major public concern. DiMoPEx plans to catalyze and stimulate interaction of scientists with policy-makers in attacking these exposure-related diseases.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng
653 a Environmental/occupational exposure to xenobiotics
653 a Human biomonitoring
653 a Noncommunicable diseases
7001 a Adam, Balazsu University of Debrecen4 aut
7001 a Albin, Mariau Karolinska Institutet,Karolinska Institute,Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)ymed-mal
7001 a Banelli, Barbarau Ospedale Policlinico San Martino,University of Genoa4 aut
7001 a Baur, Xaveru European Society for Environmental and Occupational Medicine4 aut
7001 a Belpoggi, Fiorellau Ramazzini Institute4 aut
7001 a Bolognesi, Claudiau Ospedale Policlinico San Martino4 aut
7001 a Broberg, Karinu Karolinska Institutet,Karolinska Institute4 aut0 (Swepub:lu)kgen-kbr
7001 a Gustavsson, Peru Karolinska Institutet,Karolinska Institute4 aut0 (Swepub:lu)zoof-gpe
7001 a Göen, Thomasu Friedrich-Alexander University Erlangen-Nürnberg4 aut
7001 a Fischer, Axelu Charité - University Medicine Berlin4 aut
7001 a Jarosinska, Dorota4 aut
7001 a Manservisi, Fabiana4 aut
7001 a O'Kennedy, Richardu Dublin City University4 aut
7001 a Øvrevik, Johanu Norwegian Institute of Public Health4 aut
7001 a Paunovic, Elizabet4 aut
7001 a Ritz, Beate4 aut
7001 a Scheepers, Paul T.J.u Radboud University Nijmegen4 aut
7001 a Schlünssen, Viviu Aarhus University4 aut
7001 a Schwarzenbach, Heidiu University Medical Center Hamburg-Eppendorf4 aut
7001 a Schwarze, Per E.u Norwegian Institute of Public Health4 aut
7001 a Sheils, Orlau Trinity College Dublin4 aut
7001 a Sigsgaard, Torbenu Aarhus University4 aut
7001 a Van Damme, Karelu Catholic University of Leuven4 aut
7001 a Casteleyn, Ludwineu Catholic University of Leuven4 aut
7102 a University Medical Center Hamburg-Eppendorfb University of Debrecen4 org
7730 t Journal of Occupational Medicine and Toxicologyd : Springer Science and Business Media LLCg 13:1q 13:1x 1745-6673
8564 u http://dx.doi.org/10.1186/s12995-018-0186-9x freey FULLTEXT
8564 u https://occup-med.biomedcentral.com/track/pdf/10.1186/s12995-018-0186-9
8564 8u https://lup.lub.lu.se/record/6505d680-fb46-459f-8e54-d99ef382d314
8564 8u https://doi.org/10.1186/s12995-018-0186-9
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:137582019

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