SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Roos Raymund A C)
 

Search: WFRF:(Roos Raymund A C) > Suicidal ideation i...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005444naa a2200697 4500
001oai:lup.lub.lu.se:fce5a45a-a4a9-4d30-9902-3c18f2661108
003SwePub
008170419s2013 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-375414
009oai:prod.swepub.kib.ki.se:127406537
0247 a https://lup.lub.lu.se/record/fce5a45a-a4a9-4d30-9902-3c18f26611082 URI
0247 a https://doi.org/10.1016/j.jad.2013.06.0012 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3754142 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1274065372 URI
040 a (SwePub)lud (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Hubers, Anna A M4 aut
2451 0a Suicidal ideation in a European Huntington's disease population
264 1b Elsevier BV,c 2013
300 a 11 s.
520 a BACKGROUND: Previous studies indicate increased prevalences of suicidal ideation, suicide attempts, and completed suicide in Huntington's disease (HD) compared with the general population. This study investigates correlates and predictors of suicidal ideation in HD.METHODS: The study cohort consisted of 2106 HD mutation carriers, all participating in the REGISTRY study of the European Huntington's Disease Network. Of the 1937 participants without suicidal ideation at baseline, 945 had one or more follow-up measurements. Participants were assessed for suicidal ideation by the behavioural subscale of the Unified Huntington's Disease Rating Scale (UHDRS). Correlates of suicidal ideation were analyzed using logistic regression analysis and predictors were analyzed using Cox regression analysis.RESULTS: At baseline, 169 (8.0%) mutation carriers endorsed suicidal ideation. Disease duration (odds ratio [OR]=0.96; 95% confidence interval [CI]: 0.9-1.0), anxiety (OR=2.14; 95%CI: 1.4-3.3), aggression (OR=2.41; 95%CI: 1.5-3.8), a previous suicide attempt (OR=3.95; 95%CI: 2.4-6.6), and a depressed mood (OR=13.71; 95%CI: 6.7-28.0) were independently correlated to suicidal ideation at baseline. The 4-year cumulative incidence of suicidal ideation was 9.9%. Longitudinally, the presence of a depressed mood (hazard ratio [HR]=2.05; 95%CI: 1.1-4.0) and use of benzodiazepines (HR=2.44; 95%CI: 1.2-5.0) at baseline were independent predictors of incident suicidal ideation, whereas a previous suicide attempt was not predictive.LIMITATIONS: As suicidal ideation was assessed by only one item, and participants were a selection of all HD mutation carriers, the prevalence of suicidal ideation was likely underestimated.CONCLUSIONS: Suicidal ideation in HD frequently occurs. Assessment of suicidal ideation is a priority in mutation carriers with a depressed mood and in those using benzodiazepines.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
653 a Depression
653 a Europe
653 a Female
653 a Heterozygote
653 a Humans
653 a Huntington Disease
653 a Male
653 a Middle Aged
653 a Prevalence
653 a Proportional Hazards Models
653 a Psychiatric Status Rating Scales
653 a Psychological Tests
653 a Suicidal Ideation
653 a Suicide, Attempted
653 a Cohort studies
7001 a van Duijn, Erik4 aut
7001 a Roos, Raymund A C4 aut
7001 a Craufurd, David4 aut
7001 a Rickards, Hugh4 aut
7001 a Bernhard Landwehrmeyer, G4 aut
7001 a van der Mast, Rose C4 aut
7001 a Giltay, Erik J4 aut
7001 a Petersén, Åsau Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)mphy-apn
7001 a Reimer, Janu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)neur-jre
7001 a Widner, Håkanu Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)mphy-hwi
7001 a Sundblom, Jimmy,d 1981-u Uppsala universitet,Neurokirurgi0 (Swepub:uu)jisun109
7102 a Neurologi, Lundb Sektion IV4 org
7102 a REGISTRY Investigators of the European Huntington’s Disease Network
7730 t Journal of Affective Disordersd : Elsevier BVg 151:1, s. 58-248q 151:1<58-248x 1573-2517x 0165-0327
8564 u http://dx.doi.org/10.1016/j.jad.2013.06.001x freey FULLTEXT
8564 u https://doi.org/10.1016/j.jad.2013.06.001
8564 8u https://lup.lub.lu.se/record/fce5a45a-a4a9-4d30-9902-3c18f2661108
8564 8u https://doi.org/10.1016/j.jad.2013.06.001
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-375414
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:127406537

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view