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WFRF:(Sanders Andrew J.)
 

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004212naa a2200829 4500
001oai:DiVA.org:umu-11270
003SwePub
008081204s2008 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-112702 URI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Singer, Andrew C4 aut
2451 0a Meeting Report :b Risk Assessment of Tamiflu Use Under Pandemic Conditions
264 1c 2008
338 a print2 rdacarrier
520 a On 3 October 2007, 40 participants with diverse expertise attended the workshop Tamiflu and the Environment: Implications of Use under Pandemic Conditions to assess the potential human health impact and environmental hazards associated with use of Tamiflu during an influenza pandemic. Based on the identification and risk-ranking of knowledge gaps, the consensus was that oseltamivir ethylester-phosphate (OE-P) and oseltamivir carboxylate (OC) were unlikely to pose an ecotoxicologic hazard to freshwater organisms. OC in river water might hasten the generation of OC-resistance in wildfowl, but this possibility seems less likely than the potential disruption that could be posed by OC and other pharmaceuticals to the operation of sewage treatment plants. The workgroup members agreed on the following research priorities: a) available data on the ecotoxicology of OE-P and OC should be published ; b) risk should be assessed for OC-contaminated river water generating OC-resistant viruses in wildfowl ; c) sewage treatment plant functioning due to microbial inhibition by neuraminidase inhibitors and other antimicrobials used during a pandemic should be investigated ; and d) realistic worst-case exposure scenarios should be developed. Additional modeling would be useful to identify localized areas within river catchments that might be prone to high pharmaceutical concentrations in sewage treatment plant effluent. Ongoing seasonal use of Tamiflu in Japan offers opportunities for researchers to assess how much OC enters and persists in the aquatic environment.
653 a antiviral
653 a drug
653 a ecotoxicology
653 a influenza
653 a pandemic
653 a pharmaceutical
653 a pollution
653 a sewage treatment plant
653 a Tamiflu
700a Howard, Bruce M4 aut
700a Johnson, Andrew C4 aut
700a Knowles, Chris J4 aut
700a Jackman, Simon4 aut
700a Accinelli, Cesare4 aut
700a Caracciolo, Anna Barra4 aut
700a Bernard, Ian4 aut
700a Bird, Stephen4 aut
700a Boucard, Tatiana4 aut
700a Boxall, Alistair4 aut
700a Brian, Jayne4 aut
700a Cartmell, Elise4 aut
700a Chubb, Chris4 aut
700a Churchley, John4 aut
700a Costigan, Sandra4 aut
700a Crane, Mark4 aut
700a Dempsey, Michael J4 aut
700a Dorrington, Bob4 aut
700a Fick, Jerkeru Umeå universitet,Kemiska institutionen4 aut0 (Swepub:umu)jefi0001
700a Holmes, John4 aut
700a Hutchinson, Tom4 aut
700a Karcher, Franz4 aut
700a Kelleher, Samuel L4 aut
700a Marsden, Peter4 aut
700a Noone, Gerald4 aut
700a Nunn, Miles A4 aut
700a Oxford, John4 aut
700a Rachwal, Tony4 aut
700a Roberts, Noel4 aut
700a Roberts, Mike4 aut
700a Saccà Maria, Ludovica4 aut
700a Sanders, Matthew4 aut
700a Straub, Jürg Oliver4 aut
700a Terry, Adrian4 aut
700a Thomas, Dean4 aut
700a Toovey, Stephen4 aut
700a Townsend, Rodney4 aut
700a Voulvoulis, Nick4 aut
700a Watts, Chris4 aut
700a Wells, Ursula4 aut
710a Umeå universitetb Kemiska institutionen4 org
773t Environmental Health Perspectivesg 116:11, s. 1563-7q 116:11<1563-7
856u http://www.ehponline.org/docs/2008/11310/abstract.html
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-11270

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