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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06523naa a2201597 4500 | |
| 001 | oai:prod.swepub.kib.ki.se:145313049 | |
| 003 | SwePub | |
| 008 | 240701s2020 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:a6b6540a-6095-432b-9f52-8ae1ba020ef3 | |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1453130492 URI |
| 024 | 7 | a https://doi.org/10.1038/s41467-020-19733-62 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/a6b6540a-6095-432b-9f52-8ae1ba020ef32 URI |
| 040 | a (SwePub)kid (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Steinthorsdottir, Vu deCODE Genetics4 aut |
| 245 | 1 0 | a Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women |
| 264 | c 2020-11-25 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2020 |
| 520 | a Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate with preeclampsia in the maternal genome at ZNF831/20q13 and FTO/16q12. These are previously established variants for blood pressure (BP) and the FTO variant has also been associated with body mass index (BMI). Further analysis of BP variants establishes that variants at MECOM/3q26, FGF5/4q21 and SH2B3/12q24 also associate with preeclampsia through the maternal genome. We further show that a polygenic risk score for hypertension associates with preeclampsia. However, comparison with gestational hypertension indicates that additional factors modify the risk of preeclampsia. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
| 653 | a blood | |
| 653 | a body mass | |
| 653 | a genome | |
| 653 | a meta-analysis | |
| 653 | a public health | |
| 653 | a risk assessment | |
| 700 | 1 | a McGinnis, R4 aut |
| 700 | 1 | a Williams, NO4 aut |
| 700 | 1 | a Stefansdottir, L4 aut |
| 700 | 1 | a Thorleifsson, G4 aut |
| 700 | 1 | a Shooter, Su Karolinska Institutet4 aut |
| 700 | 1 | a Fadista, Joaou Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Danish Serum Institute, Copenhagen4 aut0 (Swepub:lu)med-jft |
| 700 | 1 | a Sigurdsson, JKu Karolinska Institutet4 aut |
| 700 | 1 | a Auro, KM4 aut |
| 700 | 1 | a Berezina, G4 aut |
| 700 | 1 | a Borges, MC4 aut |
| 700 | 1 | a Bumpstead, S4 aut |
| 700 | 1 | a Bybjerg-Grauholm, J4 aut |
| 700 | 1 | a Colgiu, I4 aut |
| 700 | 1 | a Dolby, VA4 aut |
| 700 | 1 | a Dudbridge, F4 aut |
| 700 | 1 | a Engel, SM4 aut |
| 700 | 1 | a Franklin, CS4 aut |
| 700 | 1 | a Frigge, MLu University of Nottingham4 aut |
| 700 | 1 | a Frisbaek, Y4 aut |
| 700 | 1 | a Geirsson, RT4 aut |
| 700 | 1 | a Geller, F4 aut |
| 700 | 1 | a Gretarsdottir, S4 aut |
| 700 | 1 | a Gudbjartsson, DF4 aut |
| 700 | 1 | a Harmon, Q4 aut |
| 700 | 1 | a Hougaard, DM4 aut |
| 700 | 1 | a Hegay, T4 aut |
| 700 | 1 | a Helgadottir, A4 aut |
| 700 | 1 | a Hjartardottir, S4 aut |
| 700 | 1 | a Jaaskelainen, T4 aut |
| 700 | 1 | a Johannsdottir, H4 aut |
| 700 | 1 | a Jonsdottir, I4 aut |
| 700 | 1 | a Juliusdottir, T4 aut |
| 700 | 1 | a Kalsheker, N4 aut |
| 700 | 1 | a Kasimov, A4 aut |
| 700 | 1 | a Kemp, JP4 aut |
| 700 | 1 | a Kivinen, K4 aut |
| 700 | 1 | a Klungsoyr, K4 aut |
| 700 | 1 | a Lee, WK4 aut |
| 700 | 1 | a Melbye, M4 aut |
| 700 | 1 | a Miedzybrodska, Z4 aut |
| 700 | 1 | a Moffett, A4 aut |
| 700 | 1 | a Najmutdinova, D4 aut |
| 700 | 1 | a Nishanova, F4 aut |
| 700 | 1 | a Olafsdottir, T4 aut |
| 700 | 1 | a Perola, M4 aut |
| 700 | 1 | a Pipkin, FB4 aut |
| 700 | 1 | a Poston, L4 aut |
| 700 | 1 | a Prescott, G4 aut |
| 700 | 1 | a Saevarsdottir, Su Karolinska Institutet4 aut |
| 700 | 1 | a Salimbayeva, D4 aut |
| 700 | 1 | a Scaife, PJ4 aut |
| 700 | 1 | a Skotte, L4 aut |
| 700 | 1 | a Staines-Urias, E4 aut |
| 700 | 1 | a Stefansson, OA4 aut |
| 700 | 1 | a Sorensen, KM4 aut |
| 700 | 1 | a Thomsen, LCV4 aut |
| 700 | 1 | a Tragante, V4 aut |
| 700 | 1 | a Trogstad, L4 aut |
| 700 | 1 | a Simpson, NAB4 aut |
| 700 | 1 | a Laivuori, H4 aut |
| 700 | 1 | a Morgan, L4 aut |
| 700 | 1 | a Aripova, T4 aut |
| 700 | 1 | a Casas, JP4 aut |
| 700 | 1 | a Dominiczak, AF4 aut |
| 700 | 1 | a Walker, JJ4 aut |
| 700 | 1 | a Thorsteinsdottir, U4 aut |
| 700 | 1 | a Iversen, AC4 aut |
| 700 | 1 | a Feenstra, B4 aut |
| 700 | 1 | a Lawlor, DA4 aut |
| 700 | 1 | a Boyd, HA4 aut |
| 700 | 1 | a Magnus, P4 aut |
| 700 | 1 | a Laivuori, H4 aut |
| 700 | 1 | a Zakhidova, N4 aut |
| 700 | 1 | a Svyatova, G4 aut |
| 700 | 1 | a Stefansson, K4 aut |
| 700 | 1 | a Morgan, L4 aut |
| 700 | 1 | a Laivuori, H4 aut |
| 700 | 1 | a Heinonen, S4 aut |
| 700 | 1 | a Kajantie, E4 aut |
| 700 | 1 | a Kere, Ju Karolinska Institutet4 aut |
| 700 | 1 | a Kivinen, K4 aut |
| 700 | 1 | a Pouta, A4 aut |
| 700 | 1 | a Morgan, L4 aut |
| 700 | 1 | a Pipkin, FB4 aut |
| 700 | 1 | a Kalsheker, N4 aut |
| 700 | 1 | a Walker, JJ4 aut |
| 700 | 1 | a Macphail, S4 aut |
| 700 | 1 | a Kilby, M4 aut |
| 700 | 1 | a Habiba, M4 aut |
| 700 | 1 | a Williamson, C4 aut |
| 700 | 1 | a O'Shaughnessy, K4 aut |
| 700 | 1 | a O'Brien, S4 aut |
| 700 | 1 | a Cameron, A4 aut |
| 700 | 1 | a Redman, CWG4 aut |
| 700 | 1 | a Farrall, M4 aut |
| 700 | 1 | a Caulfield, M4 aut |
| 700 | 1 | a Dominiczak, AF4 aut |
| 710 | 2 | a Karolinska Institutetb deCODE Genetics4 org |
| 773 | 0 | t Nature communicationsd : Springer Science and Business Media LLCg 11:1, s. 5976-q 11:1<5976-x 2041-1723 |
| 856 | 4 | u https://www.nature.com/articles/s41467-020-19733-6.pdf |
| 856 | 4 | u http://dx.doi.org/10.1038/s41467-020-19733-6x freey FULLTEXT |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:145313049 |
| 856 | 4 8 | u https://doi.org/10.1038/s41467-020-19733-6 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/a6b6540a-6095-432b-9f52-8ae1ba020ef3 |
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- Harmon, Q
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- Hegay, T
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- Jaaskelainen, T
- Johannsdottir, H
- Jonsdottir, I
- Juliusdottir, T
- Kalsheker, N
- Kasimov, A
- Kemp, JP
- Kivinen, K
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- Lee, WK
- Melbye, M
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